Project measure / variable:   Schoonjans1   TDCA_plasma_t0_CD

ID, description, units MPD:112672   TDCA_plasma_t0_CD   plasma bile acid taurodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means30.116   ng/mL
Median of the strain means23.447   ng/mL
SD of the strain means± 27.351
Coefficient of variation (CV)0.9082
Min–max range of strain means4.812   –   131.0   ng/mL
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 122974.4766 3616.8964 6.1037 < 0.0001
Residuals 126 74664.465 592.5751


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 38.984 12.211   5 5.4611 0.3132 29.612, 60.16 0.32
BXD100 m 12.84 5.6422   5 2.5233 0.4394 4.818, 20.142 -0.63
BXD11 m 22.671 7.6963   4 3.8481 0.3395 15.21, 30.276 -0.27
BXD12 m 4.974 3.3097   3 1.9108 0.6654 1.844, 8.438 -0.92
BXD27 m 28.961 26.901   4 13.45 0.9289 9.63, 67.72 -0.04
BXD32 m 44.877 41.662   5 18.632 0.9284 14.876, 117.0 0.54
BXD34 m 5.8772 2.6495   5 1.1849 0.4508 2.364, 9.274 -0.89
BXD39 m 6.562 2.9753   3 1.7178 0.4534 4.424, 9.96 -0.86
BXD40 m 13.947 9.6391   4 4.8196 0.6911 5.542, 27.002 -0.59
BXD43 m 8.2603 5.6732   7 2.1442 0.6868 1.794, 18.102 -0.8
BXD45 m 57.12 33.051   4 16.525 0.5786 36.69, 106.5 0.99
BXD48 m 65.07 46.063   5 20.6 0.7079 33.67, 140.2 1.28
BXD48a m 18.811 4.4175   4 2.2087 0.2348 12.97, 22.69 -0.41
BXD49 m 24.224 15.515   5 6.9384 0.6405 10.156, 44.696 -0.22
BXD51 m 13.626 11.103   5 4.9652 0.8148 2.098, 32.064 -0.6
BXD53 m 37.38 34.163   4 17.082 0.914 11.608, 85.81 0.27
BXD55 m 12.075 4.4856   5 2.006 0.3715 6.156, 18.154 -0.66
BXD6 m 5.176 0.0   1   0.0 0.0 5.176, 5.176 -0.91
BXD62 m 24.57 12.396   5 5.5435 0.5045 10.408, 39.622 -0.2
BXD63 m 53.23 25.261   4 12.63 0.4746 29.258, 85.07 0.85
BXD64 m 12.663 10.608   4 5.3038 0.8377 0.85, 25.714 -0.64
BXD66 m 11.58 8.7947   5 3.9331 0.7595 5.92, 26.88 -0.68
BXD67 m 4.812 7.7426   4 3.8713 1.609 0.134, 16.312 -0.93
BXD69 m 27.942 14.409   5 6.4437 0.5157 9.982, 40.794 -0.08
BXD73 m 43.905 24.07   4 12.035 0.5482 21.386, 75.31 0.5
BXD75 m 131.0 75.49   5 33.762 0.5762 25.572, 209.7 3.69
BXD77 m 14.727 6.2531   5 2.7965 0.4246 5.914, 20.768 -0.56
BXD79 m 38.69 23.068   5 10.316 0.5962 5.46, 69.91 0.31
BXD8 m 15.43 9.2938   5 4.1563 0.6023 3.978, 25.584 -0.54
BXD81 m 19.13 11.339   3 6.5466 0.5927 7.632, 30.303 -0.4
BXD84 m 49.752 29.678   5 13.272 0.5965 11.306, 81.52 0.72
BXD87 m 107.8 47.411   5 21.203 0.4399 53.89, 164.9 2.84
BXD89 m 28.848 19.001   6 7.7571 0.6587 13.15, 62.37 -0.05
BXD90 m 13.555 8.583   5 3.8385 0.6332 3.644, 27.078 -0.61
C57BL/6J m 37.635 11.691   5 5.2285 0.3106 27.44, 57.12 0.27
DBA/2J m 27.486 12.63   4 6.3151 0.4595 15.338, 43.218 -0.1


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 38.9836 10.8864605696 60.527585427 17.439614573
BXD100 m 12.8404 10.8864605696 34.384385427 -8.703585427
BXD11 m 22.671 12.171432934 46.7579079605 -1.4159079605
BXD12 m 4.974 14.0543601617 32.7871655899 -22.8391655899
BXD27 m 28.961 12.171432934 53.0479079605 4.8740920395
BXD32 m 44.8772 10.8864605696 66.421185427 23.333214573
BXD34 m 5.8772 10.8864605696 27.421185427 -15.666785427
BXD39 m 6.562 14.0543601617 34.3751655899 -21.2511655899
BXD40 m 13.947 12.171432934 38.0339079605 -10.1399079605
BXD43 m 8.2602857143 9.2007384693 26.4682766617 -9.9477052331
BXD45 m 57.1225 12.171432934 81.2094079605 33.0355920395
BXD48 m 65.066 10.8864605696 86.609985427 43.522014573
BXD48a m 18.8105 12.171432934 42.8974079605 -5.2764079605
BXD49 m 24.2236 10.8864605696 45.767585427 2.679614573
BXD51 m 13.6264 10.8864605696 35.170385427 -7.917585427
BXD53 m 37.3795 12.171432934 61.4664079605 13.2925920395
BXD55 m 12.0748 10.8864605696 33.618785427 -9.469185427
BXD62 m 24.5696 10.8864605696 46.113585427 3.025614573
BXD63 m 53.23 12.171432934 77.3169079605 29.1430920395
BXD64 m 12.6635 12.171432934 36.7504079605 -11.4234079605
BXD66 m 11.5796 10.8864605696 33.123585427 -9.964385427
BXD67 m 4.812 12.171432934 28.8989079605 -19.2749079605
BXD69 m 27.9424 10.8864605696 49.486385427 6.398414573
BXD73 m 43.905 12.171432934 67.9919079605 19.8180920395
BXD75 m 131.0144 10.8864605696 152.558385427 109.470414573
BXD77 m 14.7268 10.8864605696 36.270785427 -6.817185427
BXD79 m 38.6896 10.8864605696 60.233585427 17.145614573
BXD8 m 15.4296 10.8864605696 36.973585427 -6.114385427
BXD81 m 19.1303333333 14.0543601617 46.9434989232 -8.6828322566
BXD84 m 49.752 10.8864605696 71.295985427 28.208014573
BXD87 m 107.786 10.8864605696 129.329985427 86.242014573
BXD89 m 28.8483333333 9.9379333756 48.5152113282 9.1814553385
BXD90 m 13.5552 10.8864605696 35.099185427 -7.988785427
C57BL/6J m 37.6352 10.8864605696 59.179185427 16.091214573
DBA/2J m 27.486 12.171432934 51.5729079605 3.3990920395




  GWAS USING LINEAR MIXED MODELS