Project measure / variable:   Schoonjans1   TCA_plasma_t0_CD

ID, description, units MPD:112668   TCA_plasma_t0_CD   plasma bile acid taurocholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurocholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means143.3   ng/mL
Median of the strain means124.6   ng/mL
SD of the strain means± 87.83
Coefficient of variation (CV)0.6127
Min–max range of strain means32.168   –   526.0   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 1288132.3701 36803.782 2.1974 0.0008
Residuals 131 2194077.9433 16748.6866


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 131.6 30.053   5 13.44 0.2284 88.16, 169.1 -0.13
BXD100 m 103.9 42.727   5 19.108 0.4111 58.15, 169.6 -0.45
BXD11 m 117.8 81.36   4 40.679 0.6905 31.404, 195.5 -0.29
BXD12 m 39.294 17.249   3 9.9588 0.439 21.156, 55.49 -1.18
BXD27 m 199.9 210.2   4 105.1 1.0517 73.58, 511.9 0.64
BXD32 m 199.7 127.5   5 57.01 0.6383 77.85, 401.0 0.64
BXD34 m 150.7 51.58   5 23.068 0.3424 65.55, 199.1 0.08
BXD39 m 256.1 44.17   3 25.501 0.1724 209.9, 297.9 1.28
BXD40 m 91.5 28.664   4 14.332 0.3132 60.87, 129.5 -0.59
BXD43 m 77.07 54.87   7 20.74 0.712 18.11, 167.8 -0.75
BXD45 m 121.9 64.84   4 32.42 0.5318 60.34, 206.2 -0.24
BXD48 m 87.88 58.36   5 26.098 0.664 41.686, 152.6 -0.63
BXD48a m 85.96 51.27   4 25.636 0.5965 24.65, 150.1 -0.65
BXD49 m 74.57 22.127   5 9.8957 0.2967 48.476, 99.69 -0.78
BXD51 m 177.5 86.04   5 38.479 0.4848 47.75, 257.1 0.39
BXD53 m 171.8 137.6   4 68.81 0.8012 81.67, 376.9 0.32
BXD55 m 32.168 10.131   5 4.5309 0.315 23.578, 48.64 -1.27
BXD6 m 297.6 163.2   5 73.0 0.5484 113.8, 482.0 1.76
BXD62 m 125.6 97.93   5 43.793 0.7794 48.804, 276.4 -0.2
BXD63 m 95.23 27.797   4 13.898 0.2919 60.82, 119.6 -0.55
BXD64 m 219.8 65.51   5 29.298 0.298 127.2, 278.2 0.87
BXD66 m 129.2 76.53   5 34.224 0.5924 63.59, 260.3 -0.16
BXD67 m 111.3 53.66   4 26.828 0.482 38.344, 165.0 -0.36
BXD69 m 192.8 114.3   5 51.1 0.5925 58.74, 293.3 0.56
BXD73 m 149.6 101.0   4 50.49 0.675 71.01, 297.6 0.07
BXD75 m 526.0 585.6   5 261.9 1.1132 62.68, 1536.0 4.36
BXD77 m 100.7 23.992   5 10.729 0.2384 82.21, 139.0 -0.49
BXD79 m 206.2 88.07   5 39.387 0.4271 84.55, 305.0 0.72
BXD8 m 138.8 103.8   5 46.401 0.7474 23.708, 284.1 -0.05
BXD81 m 66.74 65.56   3 37.85 0.9823 14.175, 140.2 -0.87
BXD84 m 123.6 44.615   5 19.953 0.361 50.17, 163.5 -0.22
BXD87 m 136.5 46.332   5 20.72 0.3395 62.07, 189.3 -0.08
BXD89 m 92.33 64.37   6 26.277 0.6971 36.222, 209.3 -0.58
BXD90 m 115.2 49.869   5 22.302 0.433 31.316, 153.6 -0.32
C57BL/6J m 61.27 17.341   5 7.7551 0.283 44.996, 87.13 -0.93
DBA/2J m 152.7 87.37   4 43.686 0.5721 68.93, 228.8 0.11


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 131.592 57.8769152429 246.0863442653 17.0976557347
BXD100 m 103.93 57.8769152429 218.4243442653 -10.5643442653
BXD11 m 117.826 64.7083584056 245.8345684083 -10.1825684083
BXD12 m 39.294 74.7187762886 187.1055628582 -108.5175628582
BXD27 m 199.8975 64.7083584056 327.9060684083 71.8889315917
BXD32 m 199.73 57.8769152429 314.2243442653 85.2356557347
BXD34 m 150.67 57.8769152429 265.1643442653 36.1756557347
BXD39 m 256.1333333333 74.7187762886 403.9448961915 108.3217704752
BXD40 m 91.505 64.7083584056 219.5135684083 -36.5035684083
BXD43 m 77.0674285714 48.9149211681 173.8328107696 -19.6979536268
BXD45 m 121.925 64.7083584056 249.9335684083 -6.0835684083
BXD48 m 87.8808 57.8769152429 202.3751442653 -26.6135442653
BXD48a m 85.9575 64.7083584056 213.9660684083 -42.0510684083
BXD49 m 74.5712 57.8769152429 189.0655442653 -39.9231442653
BXD51 m 177.49 57.8769152429 291.9843442653 62.9956557347
BXD53 m 171.7675 64.7083584056 299.7760684083 43.7589315917
BXD55 m 32.168 57.8769152429 146.6623442653 -82.3263442653
BXD6 m 297.64 57.8769152429 412.1343442653 183.1456557347
BXD62 m 125.6388 57.8769152429 240.1331442653 11.1444557347
BXD63 m 95.2325 64.7083584056 223.2410684083 -32.7760684083
BXD64 m 219.84 57.8769152429 334.3343442653 105.3456557347
BXD66 m 129.178 57.8769152429 243.6723442653 14.6836557347
BXD67 m 111.311 64.7083584056 239.3195684083 -16.6975684083
BXD69 m 192.846 57.8769152429 307.3403442653 78.3516557347
BXD73 m 149.6025 64.7083584056 277.6110684083 21.5939315917
BXD75 m 525.996 57.8769152429 640.4903442653 411.5016557347
BXD77 m 100.654 57.8769152429 215.1483442653 -13.8403442653
BXD79 m 206.19 57.8769152429 320.6843442653 91.6956557347
BXD8 m 138.8176 57.8769152429 253.3119442653 24.3232557347
BXD81 m 66.7423333333 74.7187762886 214.5538961915 -81.0692295248
BXD84 m 123.594 57.8769152429 238.0883442653 9.0996557347
BXD87 m 136.474 57.8769152429 250.9683442653 21.9796557347
BXD89 m 92.328 52.8341533956 196.8465584348 -12.1905584348
BXD90 m 115.1832 57.8769152429 229.6775442653 0.6888557347
C57BL/6J m 61.2656 57.8769152429 175.7599442653 -53.2287442653
DBA/2J m 152.715 64.7083584056 280.7235684083 24.7064315917




  GWAS USING LINEAR MIXED MODELS