Project measure / variable:   Schoonjans1   DCA_plasma_t0_HFD

ID, description, units MPD:112659   DCA_plasma_t0_HFD   plasma bile acid deoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid deoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means42.821   ng/mL
Median of the strain means32.158   ng/mL
SD of the strain means± 28.523
Coefficient of variation (CV)0.6661
Min–max range of strain means12.056   –   131.2   ng/mL
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 115936.5898 3409.8997 3.205 < 0.0001
Residuals 117 124481.6911 1063.9461


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 41.695 42.919   5 19.194 1.0294 11.808, 117.2 -0.04
BXD100 m 13.985 12.152   9 4.0507 0.8689 4.504, 41.27 -1.01
BXD11 m 22.976 0.0   1   0.0 0.0 22.976, 22.976 -0.7
BXD12 m 59.68 75.7   3 43.704 1.2684 9.974, 146.8 0.59
BXD27 m 47.127 46.87   5 20.961 0.9945 15.638, 129.1 0.15
BXD32 m 26.248 4.1716   4 2.0858 0.1589 21.356, 30.728 -0.58
BXD34 m 12.334 8.5161   4 4.2581 0.6905 3.584, 23.194 -1.07
BXD39 m 53.96 68.42   3 39.5 1.268 9.056, 132.7 0.39
BXD40 m 14.193 6.0597   4 3.0298 0.427 9.22, 22.286 -1.0
BXD43 m 12.056 6.2365   5 2.7891 0.5173 2.038, 16.422 -1.08
BXD45 m 20.159 5.1935   5 2.3226 0.2576 16.11, 28.822 -0.79
BXD48 m 56.85 28.885   5 12.918 0.5081 20.398, 92.4 0.49
BXD48a m 46.308 14.249   4 7.1244 0.3077 32.066, 65.6 0.12
BXD49 m 69.19 30.824   5 13.785 0.4455 31.862, 103.7 0.92
BXD51 m 52.14 15.911   3 9.1859 0.3051 33.874, 62.97 0.33
BXD53 m 66.46 24.985   5 11.174 0.3759 39.304, 103.5 0.83
BXD55 m 24.82 12.986   5 5.8076 0.5232 8.894, 40.128 -0.63
BXD6 m 34.453 47.975   4 23.987 1.3925 0.24706, 105.3 -0.29
BXD62 m 33.194 11.283   4 5.6413 0.3399 22.24, 48.076 -0.34
BXD63 m 93.03 22.835   5 10.212 0.2455 71.57, 130.9 1.76
BXD64 m 18.872 13.352   5 5.971 0.7075 2.484, 32.764 -0.84
BXD66 m 20.249 8.6418   3 4.9893 0.4268 12.706, 29.678 -0.79
BXD67 m 26.014 3.8686   5 1.7301 0.1487 19.634, 30.03 -0.59
BXD69 m 96.91 106.9   4 53.47 1.1035 11.62, 251.9 1.9
BXD73 m 19.595 6.866   3 3.9641 0.3504 12.598, 26.322 -0.81
BXD75 m 74.71 47.397   4 23.699 0.6345 37.82, 140.8 1.12
BXD77 m 29.326 8.307   5 3.715 0.2833 22.044, 43.11 -0.47
BXD79 m 46.43 23.47   5 10.496 0.5055 20.478, 79.56 0.13
BXD8 m 19.456 6.0104   2   4.25 0.3089 15.206, 23.706 -0.82
BXD81 m 95.11 19.614   5 8.7715 0.2062 74.29, 119.1 1.83
BXD84 m 61.82 45.493   5 20.345 0.7359 26.13, 112.4 0.67
BXD87 m 24.971 20.225   4 10.112 0.8099 5.262, 52.35 -0.63
BXD89 m 22.29 6.2305   5 2.7864 0.2795 13.852, 29.598 -0.72
BXD90 m 31.122 30.521   4 15.26 0.9807 10.212, 75.25 -0.41
C57BL/6J m 131.2 54.25   3 31.322 0.4136 88.46, 192.2 3.1
DBA/2J m 22.622 14.443   3 8.3389 0.6385 9.696, 38.212 -0.71


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 41.6948 14.5872963765 70.5841760801 12.8054239199
BXD100 m 13.9851111111 10.8727287686 35.517980692 -7.5477584698
BXD12 m 59.6813333333 18.8321186441 96.9773574802 22.3853091865
BXD27 m 47.1272 14.5872963765 76.0165760801 18.2378239199
BXD32 m 26.2475 16.3090931529 58.5468043713 -6.0518043713
BXD34 m 12.3335 16.3090931529 44.6328043713 -19.9658043713
BXD39 m 53.958 18.8321186441 91.2540241468 16.6619758532
BXD40 m 14.1925 16.3090931529 46.4918043713 -18.1068043713
BXD43 m 12.0556 14.5872963765 40.9449760801 -16.8337760801
BXD45 m 20.1588 14.5872963765 49.0481760801 -8.7305760801
BXD48 m 56.8488 14.5872963765 85.7381760801 27.9594239199
BXD48a m 46.3085 16.3090931529 78.6078043713 14.0091956287
BXD49 m 69.1864 14.5872963765 98.0757760801 40.2970239199
BXD51 m 52.1413333333 18.8321186441 89.4373574802 14.8453091865
BXD53 m 66.4608 14.5872963765 95.3501760801 37.5714239199
BXD55 m 24.8196 14.5872963765 53.7089760801 -4.0697760801
BXD6 m 34.453015 16.3090931529 66.7523193713 2.1537106287
BXD62 m 33.194 16.3090931529 65.4933043713 0.8946956287
BXD63 m 93.03 14.5872963765 121.9193760801 64.1406239199
BXD64 m 18.8716 14.5872963765 47.7609760801 -10.0177760801
BXD66 m 20.249 18.8321186441 57.5450241468 -17.0470241468
BXD67 m 26.014 14.5872963765 54.9033760801 -2.8753760801
BXD69 m 96.915 16.3090931529 129.2143043713 64.6156956287
BXD73 m 19.5953333333 18.8321186441 56.8913574802 -17.7006908135
BXD75 m 74.706 16.3090931529 107.0053043713 42.4066956287
BXD77 m 29.326 14.5872963765 58.2153760801 0.4366239199
BXD79 m 46.4304 14.5872963765 75.3197760801 17.5410239199
BXD8 m 19.456 23.0645407268 65.1341142971 -26.2221142971
BXD81 m 95.108 14.5872963765 123.9973760801 66.2186239199
BXD84 m 61.8188 14.5872963765 90.7081760801 32.9294239199
BXD87 m 24.971 16.3090931529 57.2703043713 -7.3283043713
BXD89 m 22.29 14.5872963765 51.1793760801 -6.5993760801
BXD90 m 31.122 16.3090931529 63.4213043713 -1.1773043713
C57BL/6J m 131.1533333333 18.8321186441 168.4493574802 93.8573091865
DBA/2J m 22.622 18.8321186441 59.9180241468 -14.6740241468




  GWAS USING LINEAR MIXED MODELS