Project measure / variable:   Noll1   IgG2ac_d15

ID, description, units MPD:112614   IgG2ac_d15   immunoglobulin G2a plus G2c (serum IgG2a pooled with IgG2c) area under curve (AUC) post-infection   [AUC]  day 15  
influenza A (H1N1) virus study
Data set, strains Noll1   CC RIX   34 strains     sex: f     age: 8-12 wks
Procedure immunoglobulin quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Noll1 - immunoglobulin G2a plus G2c (serum IgG2a pooled with IgG2c) area under curve (AUC) post-infection day 15



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested34 strains
Mean of the strain means5.4242   AUC
Median of the strain means5.8711   AUC
SD of the strain means± 2.0941
Coefficient of variation (CV)0.3861
Min–max range of strain means0.95789   –   9.8465   AUC
Mean sample size per strain3.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 31 487.7995 15.7355 9.9383 < 0.0001
Residuals 71 112.4152 1.5833


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
RIX:CC(002 x 021) f 3.3174 2.3256   4 1.1628 0.701 0.12061, 5.3796 -1.01
RIX:CC(003 x 051) f 3.0082 0.72521   2   0.5128 0.2411 2.4954, 3.521 -1.15
RIX:CC(003 x 062) f 0.95789 0.40031   4 0.20016 0.4179 0.43207, 1.406 -2.13
RIX:CC(013 x 041) f 2.5752 1.7076   6 0.69712 0.6631 0.82348, 5.1421 -1.36
RIX:CC(015 x 018) f 8.5879 0.41542   3 0.23984 0.0484 8.2996, 9.0641 1.51
RIX:CC(016 x 038) f 2.9985 0.29288   3 0.1691 0.0977 2.7016, 3.2872 -1.16
RIX:CC(017 x 041) f 6.4655 0.0   1   0.0 0.0 6.4655, 6.4655 0.5
RIX:CC(018 x 009) f 9.8465 0.13767   3 0.07949 0.014 9.6904, 9.9505 2.11
RIX:CC(018 x 065) f 7.6464 1.1586   4 0.57931 0.1515 6.2636, 9.0973 1.06
RIX:CC(019 x 002) f 7.2052 0.07707   2   0.0545 0.0107 7.1507, 7.2597 0.85
RIX:CC(021 x 032) f 1.3311 0.59505   3 0.34355 0.447 0.96221, 2.0176 -1.95
RIX:CC(025 x 028) f 5.7873 2.9853   4 1.4927 0.5158 1.5176, 8.4665 0.17
RIX:CC(026 x 034) f 5.1393 0.66119   3 0.38174 0.1287 4.5201, 5.8357 -0.14
RIX:CC(026 x 042) f 6.8856 0.55017   4 0.27509 0.0799 6.4216, 7.6348 0.7
RIX:CC(028 x 030) f 5.8542 1.69   4 0.84502 0.2887 3.545, 7.5606 0.21
RIX:CC(032 x 013) f 5.1123 1.2562   3 0.72524 0.2457 3.863, 6.3752 -0.15
RIX:CC(032 x 017) f 7.2136 0.97636   3 0.5637 0.1354 6.4909, 8.3243 0.85
RIX:CC(034 x 016) f 6.2278 0.74596   3 0.43068 0.1198 5.5719, 7.0393 0.38
RIX:CC(035 x 071) f 4.5405 1.4733   3 0.85063 0.3245 3.0894, 6.0351 -0.42
RIX:CC(037 x 046) f 3.8319 1.4551   3 0.84013 0.3797 2.2571, 5.1267 -0.76
RIX:CC(037 x 057) f 5.9869 1.838   3 1.0612 0.307 3.9562, 7.5366 0.27
RIX:CC(038 x 013) f 5.8879 1.1385   3 0.65733 0.1934 4.9131, 7.1392 0.22
RIX:CC(041 x 016) f 1.7504 0.53253   3 0.30746 0.3042 1.1703, 2.2171 -1.75
RIX:CC(042 x 017) f 7.7459 1.0165   4 0.50826 0.1312 6.6305, 8.8697 1.11
RIX:CC(042 x 019) f 6.8666 0.41228   4 0.20614 0.06 6.3864, 7.3722 0.69
RIX:CC(042 x 025) f 2.9857 0.65079   4 0.3254 0.218 2.59, 3.9567 -1.16
RIX:CC(043 x 037) f 6.8472 0.96296   3 0.55597 0.1406 5.9348, 7.8538 0.68
RIX:CC(051 x 005) f 4.7417 1.2982   3 0.74954 0.2738 3.251, 5.6239 -0.33
RIX:CC(051 x 009) f 6.9948 0.59417   3 0.34304 0.0849 6.6339, 7.6806 0.75
RIX:CC(052 x 007) f 6.1856 1.4494   2   1.0249 0.2343 5.1607, 7.2104 0.36
RIX:CC(057 x 052) f 6.458 0.35519   3 0.20507 0.055 6.0481, 6.6743 0.49
RIX:CC(071 x 058) f 5.4198 0.59086   2   0.4178 0.109 5.002, 5.8376 0.0
RIX:CC(075 x 021) f 5.54 0.0   1   0.0 0.0 5.54, 5.54 0.06
RIX:CC(075 x 035) f 6.4811 0.1965   2   0.13895 0.0303 6.3422, 6.6201 0.5


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
RIX:CC(002 x 021) f 3.3173775 0.6291486289 4.5718642361 2.0628907639
RIX:CC(003 x 051) f 3.0082 0.8897505238 4.782312156 1.234087844
RIX:CC(003 x 062) f 0.9578925 0.6291486289 2.2123792361 -0.2965942361
RIX:CC(013 x 041) f 2.57523 0.5136977044 3.5995141308 1.5509458692
RIX:CC(015 x 018) f 8.5879333333 0.7264782606 10.0364898429 7.1393768238
RIX:CC(016 x 038) f 2.9984666667 0.7264782606 4.4470231762 1.5499101571
RIX:CC(018 x 009) f 9.8465333333 0.7264782606 11.2950898429 8.3979768238
RIX:CC(018 x 065) f 7.6464 0.6291486289 8.9008867361 6.3919132639
RIX:CC(019 x 002) f 7.2052 0.8897505238 8.979312156 5.431087844
RIX:CC(021 x 032) f 1.3311366667 0.7264782606 2.7796931762 -0.1174198429
RIX:CC(025 x 028) f 5.78735 0.6291486289 7.0418367361 4.5328632639
RIX:CC(026 x 034) f 5.1392666667 0.7264782606 6.5878231762 3.6907101571
RIX:CC(026 x 042) f 6.885575 0.6291486289 8.1400617361 5.6310882639
RIX:CC(028 x 030) f 5.854175 0.6291486289 7.1086617361 4.5996882639
RIX:CC(032 x 013) f 5.1123333333 0.7264782606 6.5608898429 3.6637768238
RIX:CC(032 x 017) f 7.2135666667 0.7264782606 8.6621231762 5.7650101571
RIX:CC(034 x 016) f 6.2278333333 0.7264782606 7.6763898429 4.7792768238
RIX:CC(035 x 071) f 4.5405 0.7264782606 5.9890565095 3.0919434905
RIX:CC(037 x 046) f 3.8319 0.7264782606 5.2804565095 2.3833434905
RIX:CC(037 x 057) f 5.9869333333 0.7264782606 7.4354898429 4.5383768238
RIX:CC(038 x 013) f 5.8878666667 0.7264782606 7.3364231762 4.4393101571
RIX:CC(041 x 016) f 1.7504 0.7264782606 3.1989565095 0.3018434905
RIX:CC(042 x 017) f 7.745925 0.6291486289 9.0004117361 6.4914382639
RIX:CC(042 x 019) f 6.86665 0.6291486289 8.1211367361 5.6121632639
RIX:CC(042 x 025) f 2.985675 0.6291486289 4.2401617361 1.7311882639
RIX:CC(043 x 037) f 6.8472 0.7264782606 8.2957565095 5.3986434905
RIX:CC(051 x 005) f 4.7417333333 0.7264782606 6.1902898429 3.2931768238
RIX:CC(051 x 009) f 6.9948333333 0.7264782606 8.4433898429 5.5462768238
RIX:CC(052 x 007) f 6.18555 0.8897505238 7.959662156 4.411437844
RIX:CC(057 x 052) f 6.4580333333 0.7264782606 7.9065898429 5.0094768238
RIX:CC(071 x 058) f 5.4198 0.8897505238 7.193912156 3.645687844
RIX:CC(075 x 035) f 6.48115 0.8897505238 8.255262156 4.707037844




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA