Project measure / variable:   Noll1   IgG1_d10

ID, description, units MPD:112608   IgG1_d10   immunoglobulin G1 (serum IgG1) area under curve (AUC) post-infection   [AUC]  day 10  
influenza A (H1N1) virus study
Data set, strains Noll1   CC RIX   39 strains     sex: f     age: 8-12 wks
Procedure immunoglobulin quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Noll1 - immunoglobulin G1 (serum IgG1) area under curve (AUC) post-infection day 10



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested39 strains
Mean of the strain means0.90601   AUC
Median of the strain means0.51118   AUC
SD of the strain means± 1.1749
Coefficient of variation (CV)1.2968
Min–max range of strain means0.02835   –   4.9591   AUC
Mean sample size per strain3.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 152.7476 4.4926 5.7128 < 0.0001
Residuals 98 77.0672 0.7864


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
RIX:CC(002 x 021) f 1.5976 1.3232   3 0.76394 0.8282 0.11153, 2.648 0.59
RIX:CC(003 x 051) f 0.0436 0.03445   3 0.01989 0.7901 0.02201, 0.08333 -0.73
RIX:CC(005 x 020) f 0.41735 0.41417   3 0.23912 0.9924 0.14664, 0.89414 -0.42
RIX:CC(007 x 075) f 2.3967 2.7335   4 1.3668 1.1405 0.26689, 6.217 1.27
RIX:CC(013 x 026) f 0.58169 0.34598   5 0.15473 0.5948 0.26259, 0.99948 -0.28
RIX:CC(013 x 041) f 0.03798 0.04275   8 0.01511 1.1256 0.01112, 0.14142 -0.74
RIX:CC(015 x 018) f 0.93975 0.10253   3 0.05919 0.1091 0.873, 1.0578 0.03
RIX:CC(015 x 059) f 0.30568 0.17722   3 0.10232 0.5798 0.10327, 0.43296 -0.51
RIX:CC(016 x 038) f 0.93279 0.71264   3 0.41144 0.764 0.16326, 1.57 0.02
RIX:CC(017 x 041) f 0.12882 0.00311127   2   0.0022 0.0242 0.12662, 0.13102 -0.66
RIX:CC(018 x 009) f 1.0098 0.0   1   0.0 0.0 1.0098, 1.0098 0.09
RIX:CC(018 x 065) f 0.34367 0.46416   3 0.26798 1.3506 0.04814, 0.87866 -0.48
RIX:CC(019 x 002) f 1.6898 1.3634   6 0.5566 0.8068 0.05589, 3.4015 0.67
RIX:CC(025 x 028) f 0.2137 0.34958   4 0.17479 1.6359 0.01949, 0.73764 -0.59
RIX:CC(026 x 034) f 0.4291 0.27219   4 0.13609 0.6343 0.02149, 0.58497 -0.41
RIX:CC(028 x 030) f 0.07087 0.06437   5 0.02878 0.9082 0.02779, 0.18125 -0.71
RIX:CC(032 x 013) f 0.06242 0.03041   6 0.01241 0.4871 0.03192, 0.10791 -0.72
RIX:CC(032 x 017) f 3.5019 0.79984   3 0.46179 0.2284 3.0198, 4.4252 2.21
RIX:CC(034 x 016) f 0.25789 0.06987   3 0.04034 0.2709 0.18486, 0.3241 -0.55
RIX:CC(035 x 071) f 0.51118 0.68864   3 0.39759 1.3471 0.03931, 1.3014 -0.34
RIX:CC(037 x 046) f 0.02835 0.00258449   3 0.00149216 0.0912 0.02629, 0.03125 -0.75
RIX:CC(037 x 057) f 4.9591 1.3638   3 0.78737 0.275 3.3847, 5.7747 3.45
RIX:CC(038 x 013) f 0.07264 0.02719   3 0.0157 0.3743 0.04131, 0.09001 -0.71
RIX:CC(041 x 016) f 0.53817 0.84556   3 0.48818 1.5712 0.02212, 1.514 -0.31
RIX:CC(042 x 017) f 1.3293 0.72298   2   0.51122 0.5439 0.81805, 1.8405 0.36
RIX:CC(042 x 019) f 0.93057 0.0   1   0.0 0.0 0.93057, 0.93057 0.02
RIX:CC(042 x 025) f 1.3084 1.3666   3 0.78903 1.0445 0.45516, 2.8847 0.34
RIX:CC(043 x 037) f 0.37177 0.28662   9 0.09554 0.771 0.06877, 0.8489 -0.45
RIX:CC(051 x 005) f 0.59076 0.46868   4 0.23434 0.7934 0.09434, 1.2231 -0.27
RIX:CC(051 x 009) f 4.6356 3.4303   2   2.4256 0.74 2.21, 7.0612 3.17
RIX:CC(052 x 007) f 1.5657 0.98873   3 0.57084 0.6315 0.48207, 2.4188 0.56
RIX:CC(057 x 052) f 0.60674 0.41548   3 0.23988 0.6848 0.26364, 1.0687 -0.25
RIX:CC(058 x 022) f 0.13232 0.0   1   0.0 0.0 0.13232, 0.13232 -0.66
RIX:CC(062 x 046) f 0.2001 0.24846   4 0.12423 1.2417 0.0644, 0.57239 -0.6
RIX:CC(063 x 002) f 0.24523 0.23823   4 0.11912 0.9715 0.06669, 0.59595 -0.56
RIX:CC(074 x 058) f 1.5707 2.2646   3 1.3075 1.4418 0.06706, 4.1753 0.57
RIX:CC(074 x 062) f 0.06593 0.0   1   0.0 0.0 0.06593, 0.06593 -0.72
RIX:CC(075 x 021) f 0.58024 0.41981   8 0.14843 0.7235 0.13468, 1.2618 -0.28
RIX:CC(075 x 035) f 0.13058 0.0294   2   0.02079 0.2252 0.10979, 0.15137 -0.66


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
RIX:CC(002 x 021) f 1.5976433333 0.5119895402 2.6136699128 0.5816167538
RIX:CC(003 x 051) f 0.0436 0.5119895402 1.0596265795 -0.9724265795
RIX:CC(005 x 020) f 0.4173533333 0.5119895402 1.4333799128 -0.5986732462
RIX:CC(007 x 075) f 2.3966825 0.4433959483 3.2765873288 1.5167776712
RIX:CC(013 x 026) f 0.581686 0.3965853925 1.3686968043 -0.2053248043
RIX:CC(013 x 041) f 0.03797875 0.3135282818 0.6601654212 -0.5842079212
RIX:CC(015 x 018) f 0.9397466667 0.5119895402 1.9557732462 -0.0762799128
RIX:CC(015 x 059) f 0.3056766667 0.5119895402 1.3217032462 -0.7103499128
RIX:CC(016 x 038) f 0.9327866667 0.5119895402 1.9488132462 -0.0832399128
RIX:CC(017 x 041) f 0.12882 0.6270565635 1.3731933424 -1.1155533424
RIX:CC(018 x 065) f 0.34367 0.5119895402 1.3596965795 -0.6723565795
RIX:CC(019 x 002) f 1.6898133333 0.3620312757 2.4082526176 0.9713740491
RIX:CC(025 x 028) f 0.2136975 0.4433959483 1.0936023288 -0.6662073288
RIX:CC(026 x 034) f 0.429105 0.4433959483 1.3090098288 -0.4507998288
RIX:CC(028 x 030) f 0.070872 0.3965853925 0.8578828043 -0.7161388043
RIX:CC(032 x 013) f 0.0624233333 0.3620312757 0.7808626176 -0.6560159509
RIX:CC(032 x 017) f 3.5019333333 0.5119895402 4.5179599128 2.4859067538
RIX:CC(034 x 016) f 0.2578933333 0.5119895402 1.2739199128 -0.7581332462
RIX:CC(035 x 071) f 0.5111833333 0.5119895402 1.5272099128 -0.5048432462
RIX:CC(037 x 046) f 0.02835 0.5119895402 1.0443765795 -0.9876765795
RIX:CC(037 x 057) f 4.9591 0.5119895402 5.9751265795 3.9430734205
RIX:CC(038 x 013) f 0.0726433333 0.5119895402 1.0886699128 -0.9433832462
RIX:CC(041 x 016) f 0.5381733333 0.5119895402 1.5541999128 -0.4778532462
RIX:CC(042 x 017) f 1.329275 0.6270565635 2.5736483424 0.0849016576
RIX:CC(042 x 025) f 1.3084366667 0.5119895402 2.3244632462 0.2924100872
RIX:CC(043 x 037) f 0.3717688889 0.2955972988 0.9583721081 -0.2148343303
RIX:CC(051 x 005) f 0.590755 0.4433959483 1.4706598288 -0.2891498288
RIX:CC(051 x 009) f 4.6356 0.6270565635 5.8799733424 3.3912266576
RIX:CC(052 x 007) f 1.56569 0.5119895402 2.5817165795 0.5496634205
RIX:CC(057 x 052) f 0.6067366667 0.5119895402 1.6227632462 -0.4092899128
RIX:CC(062 x 046) f 0.2000975 0.4433959483 1.0800023288 -0.6798073288
RIX:CC(063 x 002) f 0.24523 0.4433959483 1.1251348288 -0.6346748288
RIX:CC(074 x 058) f 1.57071 0.5119895402 2.5867365795 0.5546834205
RIX:CC(075 x 021) f 0.58023625 0.3135282818 1.2024229212 -0.0419504212
RIX:CC(075 x 035) f 0.13058 0.6270565635 1.3749533424 -1.1137933424




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA