Project measure / variable:   Auwerx1   asp_trans_CD

ID, description, units MPD:111346   asp_trans_CD   blood aspartate transaminase amount   [U/L]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   54 strains     sex: m     age: 29wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Auwerx1 - blood aspartate transaminase amount CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested54 strains
Mean of the strain means72.99   U/L
Median of the strain means65.25   U/L
SD of the strain means± 34.931
Coefficient of variation (CV)0.4786
Min–max range of strain means22.0   –   156.0   U/L
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 53 268854.268 5072.722 3.4154 < 0.0001
Residuals 172 255459.6833 1485.2307


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 87.0 46.696   5 20.883 0.5367 44.0, 158.0 0.4
BXD100 m 33.667 12.503   3 7.2188 0.3714 25.0, 48.0 -1.13
BXD101 m 81.0 20.331   4 10.165 0.251 65.0, 109.0 0.23
BXD12 m 59.2 39.264   5 17.56 0.6633 36.0, 129.0 -0.39
BXD16 m 63.25 12.285   4 6.1424 0.1942 51.0, 77.0 -0.28
BXD27 m 53.4 33.321   5 14.902 0.624 30.0, 111.0 -0.56
BXD32 m 37.2 17.035   5 7.6184 0.4579 21.0, 62.0 -1.02
BXD34 m 22.0 3.7417   4 1.8708 0.1701 18.0, 27.0 -1.46
BXD39 m 145.8 111.6   5 49.912 0.7655 37.0, 318.0 2.08
BXD40 m 36.667 5.6862   3 3.283 0.1551 32.0, 43.0 -1.04
BXD43 m 118.7 60.86   3 35.139 0.5129 62.0, 183.0 1.31
BXD44 m 93.0 68.53   7 25.902 0.7369 27.0, 201.0 0.57
BXD45 m 30.0 33.744   4 16.872 1.1248 6.0, 80.0 -1.23
BXD48 m 35.6 11.014   5 4.9254 0.3094 20.0, 49.0 -1.07
BXD48a m 81.8 27.752   5 12.411 0.3393 54.0, 118.0 0.25
BXD49 m 93.25 4.717   4 2.3585 0.0506 89.0, 100.0 0.58
BXD50 m 71.5 14.708   4 7.3541 0.2057 62.0, 93.0 -0.04
BXD51 m 59.0 54.44   3 31.432 0.9228 9.0, 117.0 -0.4
BXD53 m 44.5 15.0   4 7.5 0.3371 25.0, 61.0 -0.82
BXD55 m 62.0 18.921   5 8.4617 0.3052 49.0, 95.0 -0.31
BXD56 m 65.0 24.062   3 13.892 0.3702 40.0, 88.0 -0.23
BXD6 m 46.0 15.895   4 7.9477 0.3456 28.0, 63.0 -0.77
BXD60 m 147.2 30.859   4 15.429 0.2096 108.0, 181.0 2.12
BXD61 m 118.3 164.5   3 94.99 1.3904 14.0, 308.0 1.3
BXD62 m 31.0 13.736   4 6.8678 0.4431 11.0, 42.0 -1.2
BXD63 m 40.0 15.524   3 8.9629 0.3881 25.0, 56.0 -0.94
BXD64 m 86.75 26.638   4 13.319 0.3071 51.0, 109.0 0.39
BXD65 m 143.0 16.432   4 8.2158 0.1149 126.0, 159.0 2.0
BXD65a m 121.0 37.954   5 16.974 0.3137 80.0, 179.0 1.37
BXD65b m 156.0 33.675   4 16.837 0.2159 123.0, 192.0 2.38
BXD66 m 33.8 15.77   5 7.0527 0.4666 8.0, 49.0 -1.12
BXD67 m 59.5 25.067   4 12.533 0.4213 30.0, 89.0 -0.39
BXD68 m 105.3 15.503   3 8.9505 0.1472 90.0, 121.0 0.92
BXD69 m 148.2 66.3   5 29.65 0.4474 61.0, 247.0 2.15
BXD70 m 50.25 35.065   4 17.533 0.6978 16.0, 98.0 -0.65
BXD71 m 55.75 14.93   4 7.4652 0.2678 44.0, 76.0 -0.49
BXD73 m 72.75 8.7321   4 4.3661 0.12 65.0, 83.0 -0.01
BXD73a m 78.6 42.182   5 18.864 0.5367 36.0, 146.0 0.16
BXD73b m 91.6 21.904   5 9.7959 0.2391 77.0, 130.0 0.53
BXD75 m 56.6 14.293   5 6.3922 0.2525 41.0, 78.0 -0.47
BXD77 m 61.6 55.33   5 24.744 0.8982 12.0, 150.0 -0.33
BXD79 m 84.6 29.083   5 13.006 0.3438 67.0, 136.0 0.33
BXD81 m 115.2 17.231   4 8.6156 0.1495 98.0, 138.0 1.21
BXD83 m 75.33 12.858   3 7.4237 0.1707 66.0, 90.0 0.07
BXD84 m 48.333 2.0817   3 1.2019 0.0431 46.0, 50.0 -0.71
BXD85 m 76.4 12.178   5 5.4461 0.1594 55.0, 84.0 0.1
BXD87 m 65.5 34.933   4 17.467 0.5333 20.0, 98.0 -0.21
BXD89 m 28.5 11.21   4 5.6051 0.3933 17.0, 42.0 -1.27
BXD90 m 28.5 9.5743   4 4.7871 0.3359 17.0, 39.0 -1.27
BXD95 m 91.75 15.777   4 7.8885 0.172 73.0, 111.0 0.54
BXD98 m 92.33 18.583   3 10.729 0.2013 77.0, 113.0 0.55
BXD99 m 67.4 14.926   5 6.6753 0.2215 55.0, 91.0 -0.16
C57BL/6J m 48.0 4.6904   4 2.3452 0.0977 42.0, 53.0 -0.72
DBA/2J m 43.0 5.9442   4 2.9721 0.1382 36.0, 50.0 -0.86


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 87.0 17.2350266438 121.0193947321 52.9806052679
BXD100 m 33.6666666667 22.2503237209 77.5855164151 -10.2521830818
BXD101 m 81.0 19.2693455847 119.0348395871 42.9651604129
BXD12 m 59.2 17.2350266438 93.2193947321 25.1806052679
BXD16 m 63.25 19.2693455847 101.2848395871 25.2151604129
BXD27 m 53.4 17.2350266438 87.4193947321 19.3806052679
BXD32 m 37.2 17.2350266438 71.2193947321 3.1806052679
BXD34 m 22.0 19.2693455847 60.0348395871 -16.0348395871
BXD39 m 145.8 17.2350266438 179.8193947321 111.7806052679
BXD40 m 36.6666666667 22.2503237209 80.5855164151 -7.2521830818
BXD43 m 118.6666666667 22.2503237209 162.5855164151 74.7478169182
BXD44 m 93.0 14.5662560983 121.7516362011 64.2483637989
BXD45 m 30.0 19.2693455847 68.0348395871 -8.0348395871
BXD48 m 35.6 17.2350266438 69.6193947321 1.5806052679
BXD48a m 81.8 17.2350266438 115.8193947321 47.7806052679
BXD49 m 93.25 19.2693455847 131.2848395871 55.2151604129
BXD50 m 71.5 19.2693455847 109.5348395871 33.4651604129
BXD51 m 59.0 22.2503237209 102.9188497484 15.0811502516
BXD53 m 44.5 19.2693455847 82.5348395871 6.4651604129
BXD55 m 62.0 17.2350266438 96.0193947321 27.9806052679
BXD56 m 65.0 22.2503237209 108.9188497484 21.0811502516
BXD6 m 46.0 19.2693455847 84.0348395871 7.9651604129
BXD60 m 147.25 19.2693455847 185.2848395871 109.2151604129
BXD61 m 118.3333333333 22.2503237209 162.2521830818 74.4144835849
BXD62 m 31.0 19.2693455847 69.0348395871 -7.0348395871
BXD63 m 40.0 22.2503237209 83.9188497484 -3.9188497484
BXD64 m 86.75 19.2693455847 124.7848395871 48.7151604129
BXD65 m 143.0 19.2693455847 181.0348395871 104.9651604129
BXD65a m 121.0 17.2350266438 155.0193947321 86.9806052679
BXD65b m 156.0 19.2693455847 194.0348395871 117.9651604129
BXD66 m 33.8 17.2350266438 67.8193947321 -0.2193947321
BXD67 m 59.5 19.2693455847 97.5348395871 21.4651604129
BXD68 m 105.3333333333 22.2503237209 149.2521830818 61.4144835849
BXD69 m 148.2 17.2350266438 182.2193947321 114.1806052679
BXD70 m 50.25 19.2693455847 88.2848395871 12.2151604129
BXD71 m 55.75 19.2693455847 93.7848395871 17.7151604129
BXD73 m 72.75 19.2693455847 110.7848395871 34.7151604129
BXD73a m 78.6 17.2350266438 112.6193947321 44.5806052679
BXD73b m 91.6 17.2350266438 125.6193947321 57.5806052679
BXD75 m 56.6 17.2350266438 90.6193947321 22.5806052679
BXD77 m 61.6 17.2350266438 95.6193947321 27.5806052679
BXD79 m 84.6 17.2350266438 118.6193947321 50.5806052679
BXD81 m 115.25 19.2693455847 153.2848395871 77.2151604129
BXD83 m 75.3333333333 22.2503237209 119.2521830818 31.4144835849
BXD84 m 48.3333333333 22.2503237209 92.2521830818 4.4144835849
BXD85 m 76.4 17.2350266438 110.4193947321 42.3806052679
BXD87 m 65.5 19.2693455847 103.5348395871 27.4651604129
BXD89 m 28.5 19.2693455847 66.5348395871 -9.5348395871
BXD90 m 28.5 19.2693455847 66.5348395871 -9.5348395871
BXD95 m 91.75 19.2693455847 129.7848395871 53.7151604129
BXD98 m 92.3333333333 22.2503237209 136.2521830818 48.4144835849
BXD99 m 67.4 17.2350266438 101.4193947321 33.3806052679
C57BL/6J m 48.0 19.2693455847 86.0348395871 9.9651604129
DBA/2J m 43.0 19.2693455847 81.0348395871 4.9651604129




  GWAS USING LINEAR MIXED MODELS