Project measure / variable:   Auwerx1   ogtt_ins_t30_HFD

ID, description, units MPD:111269   ogtt_ins_t30_HFD   insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 30 min   [µg/L]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   56 strains     sex: m     age: 17wks
Procedure hormone quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Auwerx1 - insulin, glucose tolerance test (20% glucose oral gavage, overnight fast), after 30 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested56 strains
Mean of the strain means3.3811   µg/L
Median of the strain means2.6889   µg/L
SD of the strain means± 2.122
Coefficient of variation (CV)0.6276
Min–max range of strain means0.665   –   10.854   µg/L
Mean sample size per strain4.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 55 1011.0874 18.3834 11.2776 < 0.0001
Residuals 185 301.5653 1.6301


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 1.024 0.35154   5 0.15721 0.3433 0.57, 1.43 -1.11
BXD100 m 4.2542 1.8576   5 0.83076 0.4367 2.128, 6.183 0.41
BXD101 m 3.535 0.5466   4 0.2733 0.1546 3.12, 4.34 0.07
BXD11 m 2.4295 1.5383   5 0.68797 0.6332 0.66614, 4.1425 -0.45
BXD12 m 0.7418 0.2707   5 0.12106 0.3649 0.535, 1.209 -1.24
BXD16 m 2.6918 1.3015   5 0.58204 0.4835 1.7331, 4.9743 -0.32
BXD2 m 2.6859 1.3838   5 0.61886 0.5152 1.5223, 4.2281 -0.33
BXD27 m 3.3885 0.967   4 0.4835 0.2854 2.2249, 4.5784 0.0
BXD32 m 6.2867 1.3773   3 0.7952 0.2191 4.75, 7.41 1.37
BXD34 m 1.7006 0.88814   5 0.39719 0.5223 0.59721, 2.7852 -0.79
BXD39 m 6.3233 1.6932   5 0.75722 0.2678 4.3155, 8.0355 1.39
BXD40 m 0.665 0.18358   4 0.09179 0.2761 0.48, 0.86 -1.28
BXD43 m 1.2013 0.34912   3 0.20156 0.2906 0.926, 1.594 -1.03
BXD44 m 3.9893 1.9876   6 0.81145 0.4982 1.517, 6.166 0.29
BXD45 m 2.4337 0.38918   4 0.19459 0.1599 2.065, 2.937 -0.45
BXD48 m 3.2418 1.0558   4 0.52789 0.3257 2.39, 4.736 -0.07
BXD48a m 10.854 1.1071   3 0.63918 0.102 9.588, 11.639 3.52
BXD49 m 1.9945 1.2007   4 0.60036 0.602 0.733, 3.626 -0.65
BXD50 m 4.216 1.911   5 0.85463 0.4533 1.98, 6.57 0.39
BXD51 m 3.5637 1.2612   4 0.63058 0.3539 2.36, 5.317 0.09
BXD53 m 1.6435 0.66343   5 0.29669 0.4037 0.7952, 2.5898 -0.82
BXD55 m 1.3515 0.34603   4 0.17302 0.256 1.038, 1.654 -0.96
BXD56 m 2.153 0.59536   4 0.29768 0.2765 1.572, 2.77 -0.58
BXD6 m 2.4234 1.2042   5 0.53855 0.4969 0.8158, 3.7901 -0.45
BXD60 m 5.774 0.84234   5 0.3767 0.1459 4.64, 6.62 1.13
BXD61 m 9.9428 1.612   5 0.72092 0.1621 7.627, 11.59 3.09
BXD62 m 3.4525 1.543   4 0.7715 0.4469 2.152, 5.229 0.03
BXD63 m 4.267 0.80117   4 0.40058 0.1878 3.201, 5.078 0.42
BXD64 m 1.0187 0.84916   3 0.49026 0.8336 0.099, 1.773 -1.11
BXD65 m 5.174 1.0617   3 0.61295 0.2052 3.954, 5.888 0.84
BXD65a m 4.3275 1.2051   4 0.60256 0.2785 3.08, 5.37 0.45
BXD66 m 7.0213 2.4491   4 1.2246 0.3488 4.911, 10.505 1.72
BXD67 m 1.9322 0.62119   5 0.27781 0.3215 1.4513, 2.9984 -0.68
BXD68 m 0.9735 0.57326   4 0.28663 0.5889 0.295, 1.48 -1.13
BXD69 m 1.625 0.68058   5 0.30436 0.4188 0.907, 2.444 -0.83
BXD70 m 3.0843 1.5732   3 0.90827 0.5101 1.674, 4.781 -0.14
BXD71 m 2.0233 1.0519   3 0.6073 0.5199 1.3, 3.23 -0.64
BXD73 m 2.2222 0.85237   5 0.38119 0.3836 1.356, 3.288 -0.55
BXD73a m 4.4398 2.2739   4 1.137 0.5122 1.386, 6.86 0.5
BXD73b m 2.6552 0.59272   5 0.26507 0.2232 1.914, 3.102 -0.34
BXD75 m 5.6896 2.2432   5 1.0032 0.3943 3.265, 9.027 1.09
BXD77 m 3.684 1.8757   5 0.83884 0.5091 1.53, 6.6 0.14
BXD79 m 2.236 0.88931   5 0.39771 0.3977 1.09, 3.15 -0.54
BXD8 m 0.93054 0.4858   5 0.21725 0.5221 0.51684, 1.486 -1.15
BXD81 m 2.6488 1.9578   3 1.1304 0.7391 0.4024, 3.992 -0.35
BXD83 m 6.1865 1.9436   4 0.97178 0.3142 3.678, 7.897 1.32
BXD84 m 2.267 0.7601   3 0.43884 0.3353 1.406, 2.845 -0.53
BXD85 m 1.898 0.71829   4 0.35915 0.3784 1.234, 2.905 -0.7
BXD87 m 3.703 1.2075   5 0.54002 0.3261 2.484, 5.715 0.15
BXD89 m 3.6547 1.096   4 0.54798 0.2999 2.279, 4.795 0.13
BXD90 m 2.4105 1.2326   4 0.61629 0.5113 1.447, 4.047 -0.46
BXD95 m 4.144 1.4391   5 0.6436 0.3473 2.18, 5.66 0.36
BXD98 m 2.0217 0.99234   4 0.49617 0.4908 0.797, 3.18 -0.64
BXD99 m 2.3962 0.39868   5 0.1783 0.1664 1.901, 2.905 -0.46
C57BL/6J m 3.6937 0.49994   4 0.24997 0.1353 3.223, 4.397 0.15
DBA/2J m 7.0495 2.2784   4 1.1392 0.3232 5.346, 10.366 1.73


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 1.024 0.570978625 2.1504665691 -0.1024665691
BXD100 m 4.2542 0.570978625 5.3806665691 3.1277334309
BXD101 m 3.535 0.6383735096 4.7944279115 2.2755720885
BXD11 m 2.429488 0.570978625 3.5559545691 1.3030214309
BXD12 m 0.7418 0.570978625 1.8682665691 -0.3846665691
BXD16 m 2.69182 0.570978625 3.8182865691 1.5653534309
BXD2 m 2.68588 0.570978625 3.8123465691 1.5594134309
BXD27 m 3.388475 0.6383735096 4.6479029115 2.1290470885
BXD32 m 6.2866666667 0.7371302352 7.7409287541 4.8324045792
BXD34 m 1.700582 0.570978625 2.8270485691 0.5741154309
BXD39 m 6.32326 0.570978625 7.4497265691 5.1967934309
BXD40 m 0.665 0.6383735096 1.9244279115 -0.5944279115
BXD43 m 1.2013333333 0.7371302352 2.6555954208 -0.2529287541
BXD44 m 3.9893333333 0.5212297879 5.017651917 2.9610147497
BXD45 m 2.43375 0.6383735096 3.6931779115 1.1743220885
BXD48 m 3.24175 0.6383735096 4.5011779115 1.9823220885
BXD48a m 10.8543333333 0.7371302352 12.3085954208 9.4000712459
BXD49 m 1.9945 0.6383735096 3.2539279115 0.7350720885
BXD50 m 4.216 0.570978625 5.3424665691 3.0895334309
BXD51 m 3.56375 0.6383735096 4.8231779115 2.3043220885
BXD53 m 1.64352 0.570978625 2.7699865691 0.5170534309
BXD55 m 1.3515 0.6383735096 2.6109279115 0.0920720885
BXD56 m 2.153 0.6383735096 3.4124279115 0.8935720885
BXD6 m 2.42342 0.570978625 3.5498865691 1.2969534309
BXD60 m 5.774 0.570978625 6.9004665691 4.6475334309
BXD61 m 9.9428 0.570978625 11.0692665691 8.8163334309
BXD62 m 3.4525 0.6383735096 4.7119279115 2.1930720885
BXD63 m 4.267 0.6383735096 5.5264279115 3.0075720885
BXD64 m 1.0186666667 0.7371302352 2.4729287541 -0.4355954208
BXD65 m 5.174 0.7371302352 6.6282620874 3.7197379126
BXD65a m 4.3275 0.6383735096 5.5869279115 3.0680720885
BXD66 m 7.02125 0.6383735096 8.2806779115 5.7618220885
BXD67 m 1.93222 0.570978625 3.0586865691 0.8057534309
BXD68 m 0.9735 0.6383735096 2.2329279115 -0.2859279115
BXD69 m 1.625 0.570978625 2.7514665691 0.4985334309
BXD70 m 3.0843333333 0.7371302352 4.5385954208 1.6300712459
BXD71 m 2.0233333333 0.7371302352 3.4775954208 0.5690712459
BXD73 m 2.2222 0.570978625 3.3486665691 1.0957334309
BXD73a m 4.43975 0.6383735096 5.6991779115 3.1803220885
BXD73b m 2.6552 0.570978625 3.7816665691 1.5287334309
BXD75 m 5.6896 0.570978625 6.8160665691 4.5631334309
BXD77 m 3.684 0.570978625 4.8104665691 2.5575334309
BXD79 m 2.236 0.570978625 3.3624665691 1.1095334309
BXD8 m 0.930538 0.570978625 2.0570045691 -0.1959285691
BXD81 m 2.6488 0.7371302352 4.1030620874 1.1945379126
BXD83 m 6.1865 0.6383735096 7.4459279115 4.9270720885
BXD84 m 2.267 0.7371302352 3.7212620874 0.8127379126
BXD85 m 1.898 0.6383735096 3.1574279115 0.6385720885
BXD87 m 3.703 0.570978625 4.8294665691 2.5765334309
BXD89 m 3.65475 0.6383735096 4.9141779115 2.3953220885
BXD90 m 2.4105 0.6383735096 3.6699279115 1.1510720885
BXD95 m 4.144 0.570978625 5.2704665691 3.0175334309
BXD98 m 2.02175 0.6383735096 3.2811779115 0.7623220885
BXD99 m 2.3962 0.570978625 3.5226665691 1.2697334309
C57BL/6J m 3.69375 0.6383735096 4.9531779115 2.4343220885
DBA/2J m 7.0495 0.6383735096 8.3089279115 5.7900720885




  GWAS USING LINEAR MIXED MODELS