Project measure / variable:   Xenakis1   haloperidol_conc_post

ID, description, units MPD:111179   haloperidol_conc_post   plasma haloperidol concentration, treatment group, post-treatment   [ng/dL]  
haloperidol study
Data set, strains Xenakis1   CC RIX   53 strains     sex: both     age: 11-13wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Xenakis1 - plasma haloperidol concentration, treatment group, post-treatment



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested52 strains50 strains
Mean of the strain means15.725   ng/dL 14.684   ng/dL
Median of the strain means15.166   ng/dL 13.166   ng/dL
SD of the strain means± 8.4104 ± 6.4234
Coefficient of variation (CV)0.5348 0.4374
Min–max range of strain means4.2   –   51.5   ng/dL 3.7   –   36.667   ng/dL
Mean sample size per strain2.5   mice 2.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 61.3051 61.3051 1.3967 0.2396
strain 33 5497.0227 166.5764 3.795 < 0.0001
sex:strain 33 2306.7069 69.9002 1.5925 0.0367
Residuals 120 5267.1708 43.8931


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
RIX:CC(001 x 074) f 20.0 9.8995   2   7.0 0.495 13.0, 27.0 0.51
RIX:CC(001 x 074) m 12.567 4.1789   3 2.4127 0.3325 8.7, 17.0 -0.33
RIX:CC(002 x 021) f 14.533 4.7173   3 2.7236 0.3246 9.6, 19.0 -0.14
RIX:CC(002 x 021) m 13.0 2.6458   3 1.5275 0.2035 11.0, 16.0 -0.26
RIX:CC(003 x 051) f 16.667 3.7859   3 2.1858 0.2272 14.0, 21.0 0.11
RIX:CC(003 x 051) m 13.733 7.4574   3 4.3056 0.543 5.2, 19.0 -0.15
RIX:CC(004 x 011) f 8.05 3.0006   4 1.5003 0.3727 5.1, 12.0 -0.91
RIX:CC(004 x 011) m 9.65 3.3234   2   2.35 0.3444 7.3, 12.0 -0.78
RIX:CC(005 x 001) f 22.667 2.5166   3 1.453 0.111 20.0, 25.0 0.83
RIX:CC(005 x 001) m 6.3 0.0   1   0.0 0.0 6.3, 6.3 -1.31
RIX:CC(005 x 023) f 9.75 0.07071   2   0.05 0.0073 9.7, 9.8 -0.71
RIX:CC(005 x 023) m 7.1 0.0   1   0.0 0.0 7.1, 7.1 -1.18
RIX:CC(005 x OR559) f 26.0 0.0   1   0.0 0.0 26.0, 26.0 1.22
RIX:CC(005 x OR559) m 10.6 1.6371   3 0.94516 0.1544 8.8, 12.0 -0.64
RIX:CC(006 x 043) f 24.0 10.44   3 6.0277 0.435 17.0, 36.0 0.98
RIX:CC(006 x 043) m 22.5 0.70711   2   0.5 0.0314 22.0, 23.0 1.22
RIX:CC(008 x 035) f 28.5 0.70711   2   0.5 0.0248 28.0, 29.0 1.52
RIX:CC(008 x 035) m 15.0 0.0   1   0.0 0.0 15.0, 15.0 0.05
RIX:CC(009 x 004) f 15.0 0.0   1   0.0 0.0 15.0, 15.0 -0.09
RIX:CC(009 x 004) m 12.867 7.1143   3 4.1074 0.5529 7.8, 21.0 -0.28
RIX:CC(010 x 034) f 14.5 5.0662   4 2.5331 0.3494 10.0, 21.0 -0.15
RIX:CC(010 x 034) m 29.0 15.556   2   11.0 0.5364 18.0, 40.0 2.23
RIX:CC(011 x 015) f 4.2 1.6523   3 0.95394 0.3934 2.5, 5.8 -1.37
RIX:CC(011 x 015) m 6.9667 3.5019   3 2.0218 0.5027 4.7, 11.0 -1.2
RIX:CC(011 x 042) f 16.667 4.0415   3 2.3333 0.2425 12.0, 19.0 0.11
RIX:CC(011 x 042) m 13.667 2.0817   3 1.2019 0.1523 12.0, 16.0 -0.16
RIX:CC(012 x 004) f 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.92
RIX:CC(012 x 004) m 9.38 3.3425   5 1.4948 0.3563 4.4, 12.0 -0.83
RIX:CC(012 x 016) f 19.25 2.0616   4 1.0308 0.1071 17.0, 21.0 0.42
RIX:CC(012 x 016) m 14.0 5.6569   2   4.0 0.4041 10.0, 18.0 -0.11
RIX:CC(012 x 032) f 16.067 13.661   3 7.887 0.8502 4.2, 31.0 0.04
RIX:CC(012 x 032) m 14.0 1.0   3 0.57735 0.0714 13.0, 15.0 -0.11
RIX:CC(013 x 041) f 28.0 2.6458   3 1.5275 0.0945 25.0, 30.0 1.46
RIX:CC(013 x 041) m 25.667 3.7859   3 2.1858 0.1475 23.0, 30.0 1.71
RIX:CC(014 x 026) f 18.333 3.0551   3 1.7638 0.1666 15.0, 21.0 0.31
RIX:CC(014 x 026) m 13.333 4.9329   3 2.848 0.37 10.0, 19.0 -0.21
RIX:CC(015 x 005) f 10.2 4.7032   3 2.7154 0.4611 5.6, 15.0 -0.66
RIX:CC(015 x 005) m 10.0 0.0   2   0.0 0.0 10.0, 10.0 -0.73
RIX:CC(016 x 024) f 8.5 0.0   1   0.0 0.0 8.5, 8.5 -0.86
RIX:CC(016 x 024) m 17.033 8.4973   3 4.9059 0.4989 9.1, 26.0 0.37
RIX:CC(017 x 004) f 15.0 2.6458   3 1.5275 0.1764 13.0, 18.0 -0.09
RIX:CC(017 x 004) m 20.333 9.4516   3 5.4569 0.4648 13.0, 31.0 0.88
RIX:CC(018 x 010) f 8.9333 0.55076   3 0.31798 0.0617 8.3, 9.3 -0.81
RIX:CC(018 x 010) m 12.133 3.3843   3 1.9539 0.2789 8.4, 15.0 -0.4
RIX:CC(019 x 002) f 23.8 17.813   3 10.285 0.7485 6.4, 42.0 0.96
RIX:CC(019 x 002) m 23.0 8.7178   3 5.0332 0.379 17.0, 33.0 1.29
RIX:CC(019 x 004) f 18.5 12.021   2   8.5 0.6498 10.0, 27.0 0.33
RIX:CC(019 x 004) m 9.9 7.2125   2   5.1 0.7285 4.8, 15.0 -0.74
RIX:CC(019 x 065) f 51.5 30.406   2   21.5 0.5904 30.0, 73.0 4.25
RIX:CC(021 x 032) f 13.0 2.8284   2   2.0 0.2176 11.0, 15.0 -0.32
RIX:CC(021 x 032) m 23.0 0.0   1   0.0 0.0 23.0, 23.0 1.29
RIX:CC(023 x 019) m 6.9 0.0   1   0.0 0.0 6.9, 6.9 -1.21
RIX:CC(024 x 023) f 8.7333 0.55076   3 0.31798 0.0631 8.2, 9.3 -0.83
RIX:CC(024 x 023) m 11.15 2.6163   2   1.85 0.2346 9.3, 13.0 -0.55
RIX:CC(025 x 028) f 5.8 0.0   1   0.0 0.0 5.8, 5.8 -1.18
RIX:CC(025 x 028) m 11.96 2.9168   5 1.3045 0.2439 6.8, 14.0 -0.42
RIX:CC(026 x 042) f 20.0 10.0   3 5.7735 0.5 10.0, 30.0 0.51
RIX:CC(026 x 042) m 16.7 9.564   3 5.5218 0.5727 8.1, 27.0 0.31
RIX:CC(028 x 030) f 22.0 8.4853   2   6.0 0.3857 16.0, 28.0 0.75
RIX:CC(028 x 030) m 23.0 9.0   3 5.1962 0.3913 14.0, 32.0 1.29
RIX:CC(030 x 013) f 6.55 0.07071   2   0.05 0.0108 6.5, 6.6 -1.09
RIX:CC(030 x 013) m 17.0 2.6458   3 1.5275 0.1556 15.0, 20.0 0.36
RIX:CC(031 x 018) f 7.9 9.6597   3 5.577 1.2227 1.4, 19.0 -0.93
RIX:CC(031 x 018) m 13.0 0.0   1   0.0 0.0 13.0, 13.0 -0.26
RIX:CC(032 x 017) f 11.767 5.8876   3 3.3992 0.5004 6.3, 18.0 -0.47
RIX:CC(032 x 017) m 30.667 5.5076   3 3.1798 0.1796 27.0, 37.0 2.49
RIX:CC(033 x 040) f 17.5 0.70711   2   0.5 0.0404 17.0, 18.0 0.21
RIX:CC(033 x 040) m 16.3 11.188   3 6.4594 0.6864 7.9, 29.0 0.25
RIX:CC(035 x 007) f 8.3 5.2326   2   3.7 0.6304 4.6, 12.0 -0.88
RIX:CC(035 x 007) m 11.15 5.4447   2   3.85 0.4883 7.3, 15.0 -0.55
RIX:CC(036 x 052) f 29.0 0.0   1   0.0 0.0 29.0, 29.0 1.58
RIX:CC(036 x 052) m 13.9 7.2125   2   5.1 0.5189 8.8, 19.0 -0.12
RIX:CC(038 x 022) f 6.65 0.35355   2   0.25 0.0532 6.4, 6.9 -1.08
RIX:CC(041 x 012) f 17.133 13.764   3 7.9468 0.8034 8.4, 33.0 0.17
RIX:CC(041 x 012) m 36.667 12.014   3 6.9362 0.3277 25.0, 49.0 3.42
RIX:CC(042 x 014) f 28.0 11.314   2   8.0 0.4041 20.0, 36.0 1.46
RIX:CC(042 x 014) m 12.167 3.4034   3 1.965 0.2797 9.5, 16.0 -0.39
RIX:CC(042 x 023) f 10.0 0.0   1   0.0 0.0 10.0, 10.0 -0.68
RIX:CC(042 x 023) m 16.667 2.8868   3 1.6667 0.1732 15.0, 20.0 0.31
RIX:CC(042 x 025) f 15.667 2.3094   3 1.3333 0.1474 13.0, 17.0 -0.01
RIX:CC(042 x 025) m 13.0 0.0   1   0.0 0.0 13.0, 13.0 -0.26
RIX:CC(047 x 057) f 11.333 3.2146   3 1.8559 0.2836 9.0, 15.0 -0.52
RIX:CC(047 x 057) m 15.0 0.0   1   0.0 0.0 15.0, 15.0 0.05
RIX:CC(050 x 011) f 6.6667 1.1719   3 0.67659 0.1758 5.8, 8.0 -1.08
RIX:CC(050 x 011) m 10.567 2.6764   3 1.5452 0.2533 7.7, 13.0 -0.64
RIX:CC(051 x 005) f 20.5 9.1924   2   6.5 0.4484 14.0, 27.0 0.57
RIX:CC(051 x 005) m 13.0 2.8284   2   2.0 0.2176 11.0, 15.0 -0.26
RIX:CC(051 x 062) f 8.65 4.7376   2   3.35 0.5477 5.3, 12.0 -0.84
RIX:CC(051 x 062) m 12.433 4.8211   3 2.7835 0.3878 9.6, 18.0 -0.35
RIX:CC(052 x 009) f 22.0 10.536   3 6.0828 0.4789 12.0, 33.0 0.75
RIX:CC(052 x 009) m 3.7 0.0   1   0.0 0.0 3.7, 3.7 -1.71
RIX:CC(057 x 008) f 15.333 6.0277   3 3.4801 0.3931 9.0, 21.0 -0.05
RIX:CC(057 x 008) m 16.5 4.9497   2   3.5 0.3 13.0, 20.0 0.28
RIX:CC(061 x 038) f 7.0667 4.4736   3 2.5828 0.6331 2.2, 11.0 -1.03
RIX:CC(061 x 038) m 9.075 4.954   4 2.477 0.5459 4.6, 16.0 -0.87
RIX:CC(062 x 047) f 16.0 0.0   1   0.0 0.0 16.0, 16.0 0.03
RIX:CC(065 x 003) f 17.333 3.0551   3 1.7638 0.1763 14.0, 20.0 0.19
RIX:CC(065 x 003) m 15.3 6.1539   3 3.5529 0.4022 9.9, 22.0 0.1
RIX:CC(074 x 002) f 10.567 1.2503   3 0.72188 0.1183 9.7, 12.0 -0.61
RIX:CC(074 x 002) m 9.75 6.0104   2   4.25 0.6165 5.5, 14.0 -0.77
RIX:CC(OR559 x 031) f 7.6333 2.9501   3 1.7033 0.3865 5.5, 11.0 -0.96
RIX:CC(OR559 x 031) m 13.933 6.3256   3 3.6521 0.454 8.8, 21.0 -0.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
RIX:CC(001 x 074) f 20.0 4.6847139869 29.2754076617 10.7245923383
RIX:CC(001 x 074) m 12.5666666667 3.8250529529 20.1400053092 4.9933280241
RIX:CC(002 x 021) f 14.5333333333 3.8250529529 22.1066719759 6.9599946908
RIX:CC(002 x 021) m 13.0 3.8250529529 20.5733386425 5.4266613575
RIX:CC(003 x 051) f 16.6666666667 3.8250529529 24.2400053092 9.0933280241
RIX:CC(003 x 051) m 13.7333333333 3.8250529529 21.3066719759 6.1599946908
RIX:CC(004 x 011) f 8.05 3.312593028 14.6087036559 1.4912963441
RIX:CC(004 x 011) m 9.65 4.6847139869 18.9254076617 0.3745923383
RIX:CC(006 x 043) f 24.0 3.8250529529 31.5733386425 16.4266613575
RIX:CC(006 x 043) m 22.5 4.6847139869 31.7754076617 13.2245923383
RIX:CC(010 x 034) f 14.5 3.312593028 21.0587036559 7.9412963441
RIX:CC(010 x 034) m 29.0 4.6847139869 38.2754076617 19.7245923383
RIX:CC(011 x 015) f 4.2 3.8250529529 11.7733386425 -3.3733386425
RIX:CC(011 x 015) m 6.9666666667 3.8250529529 14.5400053092 -0.6066719759
RIX:CC(011 x 042) f 16.6666666667 3.8250529529 24.2400053092 9.0933280241
RIX:CC(011 x 042) m 13.6666666667 3.8250529529 21.2400053092 6.0933280241
RIX:CC(012 x 016) f 19.25 3.312593028 25.8087036559 12.6912963441
RIX:CC(012 x 016) m 14.0 4.6847139869 23.2754076617 4.7245923383
RIX:CC(012 x 032) f 16.0666666667 3.8250529529 23.6400053092 8.4933280241
RIX:CC(012 x 032) m 14.0 3.8250529529 21.5733386425 6.4266613575
RIX:CC(013 x 041) f 28.0 3.8250529529 35.5733386425 20.4266613575
RIX:CC(013 x 041) m 25.6666666667 3.8250529529 33.2400053092 18.0933280241
RIX:CC(014 x 026) f 18.3333333333 3.8250529529 25.9066719759 10.7599946908
RIX:CC(014 x 026) m 13.3333333333 3.8250529529 20.9066719759 5.7599946908
RIX:CC(015 x 005) f 10.2 3.8250529529 17.7733386425 2.6266613575
RIX:CC(015 x 005) m 10.0 4.6847139869 19.2754076617 0.7245923383
RIX:CC(017 x 004) f 15.0 3.8250529529 22.5733386425 7.4266613575
RIX:CC(017 x 004) m 20.3333333333 3.8250529529 27.9066719759 12.7599946908
RIX:CC(018 x 010) f 8.9333333333 3.8250529529 16.5066719759 1.3599946908
RIX:CC(018 x 010) m 12.1333333333 3.8250529529 19.7066719759 4.5599946908
RIX:CC(019 x 002) f 23.8 3.8250529529 31.3733386425 16.2266613575
RIX:CC(019 x 002) m 23.0 3.8250529529 30.5733386425 15.4266613575
RIX:CC(019 x 004) f 18.5 4.6847139869 27.7754076617 9.2245923383
RIX:CC(019 x 004) m 9.9 4.6847139869 19.1754076617 0.6245923383
RIX:CC(024 x 023) f 8.7333333333 3.8250529529 16.3066719759 1.1599946908
RIX:CC(024 x 023) m 11.15 4.6847139869 20.4254076617 1.8745923383
RIX:CC(026 x 042) f 20.0 3.8250529529 27.5733386425 12.4266613575
RIX:CC(026 x 042) m 16.7 3.8250529529 24.2733386425 9.1266613575
RIX:CC(028 x 030) f 22.0 4.6847139869 31.2754076617 12.7245923383
RIX:CC(028 x 030) m 23.0 3.8250529529 30.5733386425 15.4266613575
RIX:CC(030 x 013) f 6.55 4.6847139869 15.8254076617 -2.7254076617
RIX:CC(030 x 013) m 17.0 3.8250529529 24.5733386425 9.4266613575
RIX:CC(032 x 017) f 11.7666666667 3.8250529529 19.3400053092 4.1933280241
RIX:CC(032 x 017) m 30.6666666667 3.8250529529 38.2400053092 23.0933280241
RIX:CC(033 x 040) f 17.5 4.6847139869 26.7754076617 8.2245923383
RIX:CC(033 x 040) m 16.3 3.8250529529 23.8733386425 8.7266613575
RIX:CC(035 x 007) f 8.3 4.6847139869 17.5754076617 -0.9754076617
RIX:CC(035 x 007) m 11.15 4.6847139869 20.4254076617 1.8745923383
RIX:CC(041 x 012) f 17.1333333333 3.8250529529 24.7066719759 9.5599946908
RIX:CC(041 x 012) m 36.6666666667 3.8250529529 44.2400053092 29.0933280241
RIX:CC(042 x 014) f 28.0 4.6847139869 37.2754076617 18.7245923383
RIX:CC(042 x 014) m 12.1666666667 3.8250529529 19.7400053092 4.5933280241
RIX:CC(050 x 011) f 6.6666666667 3.8250529529 14.2400053092 -0.9066719759
RIX:CC(050 x 011) m 10.5666666667 3.8250529529 18.1400053092 2.9933280241
RIX:CC(051 x 005) f 20.5 4.6847139869 29.7754076617 11.2245923383
RIX:CC(051 x 005) m 13.0 4.6847139869 22.2754076617 3.7245923383
RIX:CC(051 x 062) f 8.65 4.6847139869 17.9254076617 -0.6254076617
RIX:CC(051 x 062) m 12.4333333333 3.8250529529 20.0066719759 4.8599946908
RIX:CC(057 x 008) f 15.3333333333 3.8250529529 22.9066719759 7.7599946908
RIX:CC(057 x 008) m 16.5 4.6847139869 25.7754076617 7.2245923383
RIX:CC(061 x 038) f 7.0666666667 3.8250529529 14.6400053092 -0.5066719759
RIX:CC(061 x 038) m 9.075 3.312593028 15.6337036559 2.5162963441
RIX:CC(065 x 003) f 17.3333333333 3.8250529529 24.9066719759 9.7599946908
RIX:CC(065 x 003) m 15.3 3.8250529529 22.8733386425 7.7266613575
RIX:CC(074 x 002) f 10.5666666667 3.8250529529 18.1400053092 2.9933280241
RIX:CC(074 x 002) m 9.75 4.6847139869 19.0254076617 0.4745923383
RIX:CC(OR559 x 031) f 7.6333333333 3.8250529529 15.2066719759 0.0599946908
RIX:CC(OR559 x 031) m 13.9333333333 3.8250529529 21.5066719759 6.3599946908


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
RIX:CC(001 x 074) both 16.2833333333 3.0239698755 22.2705832339 10.2960834328
RIX:CC(002 x 021) both 13.7666666667 2.7047208814 19.121825777 8.4115075563
RIX:CC(003 x 051) both 15.2 2.7047208814 20.5551591104 9.8448408896
RIX:CC(004 x 011) both 8.85 2.8687897147 14.5300039819 3.1699960181
RIX:CC(006 x 043) both 23.25 3.0239698755 29.2372499005 17.2627500995
RIX:CC(010 x 034) both 21.75 2.8687897147 27.4300039819 16.0699960181
RIX:CC(011 x 015) both 5.5833333333 2.7047208814 10.9384924437 0.228174223
RIX:CC(011 x 042) both 15.1666666667 2.7047208814 20.521825777 9.8115075563
RIX:CC(012 x 016) both 16.625 2.8687897147 22.3050039819 10.9449960181
RIX:CC(012 x 032) both 15.0333333333 2.7047208814 20.3884924437 9.678174223
RIX:CC(013 x 041) both 26.8333333333 2.7047208814 32.1884924437 21.478174223
RIX:CC(014 x 026) both 15.8333333333 2.7047208814 21.1884924437 10.478174223
RIX:CC(015 x 005) both 10.1 3.0239698755 16.0872499005 4.1127500995
RIX:CC(017 x 004) both 17.6666666667 2.7047208814 23.021825777 12.3115075563
RIX:CC(018 x 010) both 10.5333333333 2.7047208814 15.8884924437 5.178174223
RIX:CC(019 x 002) both 23.4 2.7047208814 28.7551591104 18.0448408896
RIX:CC(019 x 004) both 14.2 3.312593028 20.7587036559 7.6412963441
RIX:CC(024 x 023) both 9.9416666667 3.0239698755 15.9289165672 3.9544167661
RIX:CC(026 x 042) both 18.35 2.7047208814 23.7051591104 12.9948408896
RIX:CC(028 x 030) both 22.5 3.0239698755 28.4872499005 16.5127500995
RIX:CC(030 x 013) both 11.775 3.0239698755 17.7622499005 5.7877500995
RIX:CC(032 x 017) both 21.2166666667 2.7047208814 26.571825777 15.8615075563
RIX:CC(033 x 040) both 16.9 3.0239698755 22.8872499005 10.9127500995
RIX:CC(035 x 007) both 9.725 3.312593028 16.2837036559 3.1662963441
RIX:CC(041 x 012) both 26.9 2.7047208814 32.2551591104 21.5448408896
RIX:CC(042 x 014) both 20.0833333333 3.0239698755 26.0705832339 14.0960834328
RIX:CC(050 x 011) both 8.6166666667 2.7047208814 13.971825777 3.2615075563
RIX:CC(051 x 005) both 16.75 3.312593028 23.3087036559 10.1912963441
RIX:CC(051 x 062) both 10.5416666667 3.0239698755 16.5289165672 4.5544167661
RIX:CC(057 x 008) both 15.9166666667 3.0239698755 21.9039165672 9.9294167661
RIX:CC(061 x 038) both 8.0708333333 2.5300347163 13.080125994 3.0615406727
RIX:CC(065 x 003) both 16.3166666667 2.7047208814 21.671825777 10.9615075563
RIX:CC(074 x 002) both 10.1583333333 3.0239698755 16.1455832339 4.1710834328
RIX:CC(OR559 x 031) both 10.7833333333 2.7047208814 16.1384924437 5.428174223




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA