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Project data set: Sandell1   (2012)

Project Ear wound healing and articular cartilage regeneration in 6 inbred and 9 LGXSM recombinant inbred strains of mice

Bilateral ear punctures were made in 6-wk old mice and healing outcomes were measured after 30 d. At 8 wks of age, acute full-thickness articular cartilage injuries were introduced in the trochlear groove. Mouse knee joints were sectioned at indicated times post-injury and stained to evaluate regeneration. Time course analysis showed no significant regeneration until 16 wks post-wounding.

Study design: baseline survey; 1 cohort.
15 strains tested     female male     Test age: various
Sample sizes are 5.6 on average. ... Caution, some N ≤ 2 are present  [details]

Investigators Sandell LJ     [Project details, papers, citing]

Protocol View phenotyping protocol and methods

Sandell1
measurements



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              Ontologies


wound healing         metric  
Sandell1
ear cartilage wound healing 30d post-injury   [mm] 15 strains   age 10wks
  LGXSM
 
wound healing         histopathology  
Sandell1
articular cartilage wound healing post-injury [score]        
• 12wks  • 16wks      comparison  
15 strains   age 20wks
  LGXSM


  
Reference
Rai MF, Hashimoto S, Johnson EE, Janiszak KL, Fitzgerald J, Heber-Katz E, Cheverud JM, Sandell LJ. Heritability of articular cartilage regeneration and its association with ear wound healing in mice. Arthritis Rheum. 2012 Jul;64(7):2300-10. doi: 10.1002/art.34396.     PubMed 22275233     MGI     FullText


Mice

Strain and animal info

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Changelog

One update or correction was posted since MPD release in May 2014  

Sandell1
downloads


Individual animal data
Table format (.csv)
All individual animal data, table format, one row per animal and one column per measurement.
Individual animal data
List format (.csv)
All numeric animal data values, one row per animal per measurement.
Strain means (.csv) Strain means with SD, N, other summary statistics. One row per strain / sex / measurement.
No supplemental data for this project. 

 See also MPD's general data download page for other options.





 




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