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Project data set: Petkova1   (2007)

Project Aging study: Peripheral blood leukocytes (PBL profiles) in 32 inbred strains of mice

An investigation of aging effects on immune system. Animals were evaluated using flow cytometry.

Study design: aging study (longitudinal); 1 cohort.
32 strains tested     female male     Test age: 6, 12, 18, 24 mo

Investigators Petkova S, Roopenian D   [Details, papers]
The Jackson Laboratory Nathan Shock Center

Protocol View phenotyping protocol and methods

Petkova1
measurements



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For downloads and additional info see bottom of page...  


blood — hematology — cell counts         CBC  
Petkova1
white blood cell count (WBC) [n/µL]  
      • 6mo  • 12mo  • 18mo  • 24mo    • age comparison  
32 strains   ages shown
  Inbred
Petkova1
eosinophil differential [%]  
      • 6mo  • 12mo  • 18mo  • 24mo    • age comparison  
32 strains   ages shown
  Inbred
Petkova1
lymphocyte differential [%]  
      • 6mo  • 12mo  • 18mo  • 24mo    • age comparison  
32 strains   ages shown
  Inbred
Petkova1
monocyte differential [%]  
      • 6mo  • 12mo  • 18mo  • 24mo    • age comparison  
32 strains   ages shown
  Inbred
Petkova1
neutrophil differential [%]  
      • 6mo  • 12mo  • 18mo  • 24mo    • age comparison  
32 strains   ages shown
  Inbred
 
immune system — cell counts         flow cytometry  
Petkova1
B cells [%]  
      • 6mo  • 12mo  • 18mo  • 24mo    • age comparison  
32 strains   ages shown
  Inbred
Petkova1
NK cells [%]  
      • 6mo  • 12mo  • 18mo  • 24mo    • age comparison  
32 strains   ages shown
  Inbred
Petkova1
CD4 T cells [%]  
      • 6mo  • 12mo  • 18mo  • 24mo    • age comparison  
32 strains   ages shown
  Inbred
Petkova1
CD4 T cells - naive cells [%]  
      • 6mo  • 12mo  • 18mo  • 24mo    • age comparison  
32 strains   ages shown
  Inbred
Petkova1
CD4 T cells - central memory cells [%]  
      • 6mo  • 12mo  • 18mo  • 24mo    • age comparison  
32 strains   ages shown
  Inbred
Petkova1
CD4 T cells - effector memory cells [%]  
      • 6mo  • 12mo  • 18mo  • 24mo    • age comparison  
32 strains   ages shown
  Inbred
Petkova1
CD4 T cells - effector cells [%]  
      • 6mo  • 12mo  • 18mo  • 24mo    • age comparison  
32 strains   ages shown
  Inbred
Petkova1
CD8 T cells [%]  
      • 6mo  • 12mo  • 18mo  • 24mo    • age comparison  
32 strains   ages shown
  Inbred
Petkova1
CD8 T cells - naive cells [%]  
      • 6mo  • 12mo  • 18mo  • 24mo    • age comparison  
32 strains   ages shown
  Inbred
Petkova1
CD8 T cells - central memory cells [%]  
      • 6mo  • 12mo  • 18mo  • 24mo    • age comparison  
32 strains   ages shown
  Inbred
Petkova1
CD8 T cells - effector memory cells [%]  
      • 6mo  • 12mo  • 18mo  • 24mo    • age comparison  
32 strains   ages shown
  Inbred
Petkova1
CD8 T cells - effector cells [%]  
      • 6mo  • 12mo  • 18mo  • 24mo    • age comparison  
32 strains   ages shown
  Inbred



Number of mice tested per strain, for each measurement

  
Changelog There has been one update or correction to the data set since MPD release in Jun 2009  
Reference
Petkova SB, Yuan R, Tsaih SW, Schott W, Roopenian DC, Paigen B. Genetic influence on immune phenotype revealed strain-specific variations in peripheral blood lineages. Physiol Genomics. 2008 Aug 15;34(3):304-14. Epub 2008 Jun 10.     PubMed 18544662     MGI     FullText

Related papers
Mice
Strain and animal info
Note
Please note: Low sample sizes (N < 5) are present. [View table]

Petkova1
downloads


Individual animal data
Table format (.csv)
Individual animal data in table format, with one row per animal and one column per measurement.
Individual animal data
List format (.csv)
Individual animal data organized as one row per animal / measurement reading.
Strain means (.csv) Strain means with SD, N, other summary statistics. One row per strain / sex / measurement.
No supplemental data for this project. 

 See also the MPD download center for more general data download options.





 




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