blood — clinical chemistry         metabolic panel   Paigen1 alanine aminotransferase (plasma ALT)   [IU/L]   high-fat diet   8wks 43 strains   age 15-19wks   Inbred Paigen1 bile salts (plasma)   [µmol/L]   high-fat diet   8wks 43 strains   age 15-19wks   Inbred   blood — lipids         lipid profile   Paigen1 HDL cholesterol (plasma)   high-fat diet   8wks       • amount  • % of total plasma cholesterol  43 strains   age 15-19wks   Inbred Paigen1 plasma cholesterol not in the HDL fraction   [mg/dL]   high-fat diet   8wks 43 strains   age 15-19wks   Inbred Paigen1 total cholesterol (plasma)   [mg/dL]   high-fat diet   8wks 43 strains   age 15-19wks   Inbred   body weight         scales   Paigen1 body weight [g]     baseline and  high-fat diet 8wks       • start   • after 8wks on diet   • Δchange    • comparison   43 strains   age 7-11wks                 at baseline   Inbred   cardiovascular — atherosclerosis         histopathology   Paigen1 fatty streak aortic lesion size   [µm2]   high-fat diet   8wks 43 strains   age 15-19wks   Inbred   gallbladder — pathology and gallstones         gravimetry   Paigen1 gallbladder volume   [µL]   high-fat diet   8wks 43 strains   age 15-19wks   Inbred   gallbladder — pathology and gallstones         histopathology   Paigen1 gallbladder pathology (0-4) [score]   high-fat diet   8wks         • mucin    • arc    • filaments          liquid crystals:   • small    • aggregated    • fused    • comparison           cholesterol monohydrate crystals:   • all  43 strains   age 15-19wks   Inbred Paigen1 gallstones [n]   high-fat diet   8wks       • sandy  • true  • all  • presence score [0/1]    • comparison   43 strains   age 15-19wks   Inbred   liver — lipid homeostasis         lipid profile   Paigen1 hepatic cholesterol concentration [mg]   high-fat diet   8wks       • free  • esterified  • total   • free to esterified ratio  43 strains   age 15-19wks   Inbred   liver — pathology         histopathology   Paigen1 liver pathology (0-4) [score]   high-fat diet   8wks       • images  • microvacuoles  • macrovacuoles  • inflammation  43 strains   age 15-19wks   Inbred   liver — weight         scales   Paigen1 liver weight at sacrifice   [g]   high-fat diet   8wks 43 strains   age 15-19wks   Inbred local experiment parameter   Paigen1 age at start of diet   [d] 43 strains     Inbred

Number of mice tested per strain, for each measurement