appearance and coat color         SHIRPA   Jaxpheno7 body presentation [score]         • body position  • pelvic elevation  • tail elevation  • hindlimb splay  • limb pattern  6 strains   age 10wks   Inbred Jaxpheno7 color evaluation of plantar surface and forelimb digits during supine restraint (score 0-2)   [score] 6 strains   age 10wks   Inbred   behavior — anxiety         SHIRPA   Jaxpheno7 degree of behavioral inhibition or arousal [score]         • transfer arousal  • freezing  6 strains   age 10wks   Inbred Jaxpheno7 frequency of behavioral displacement (jar) [n]         • defecation  • urination  6 strains   age 10wks   Inbred Jaxpheno7 frequency of behavioral displacement (arena) [n]         • defecation  • urination  6 strains   age 10wks   Inbred   behavior — balance and coordination         rotarod   Jaxpheno7 latency to fall from stationary rotarod during habituation period [s]         • trial1  • trial2  • trial3  • average    • comparison   6 strains   age 10wks   Inbred Jaxpheno7 latency to fall from rotarod at constant 4 rpm [s]         • trial1  • trial2  • trial3  • average    • comparison   6 strains   age 10wks   Inbred Jaxpheno7 latency to fall from accelerating (60 rpm/min) rotarod [s]         • trial1  • trial2  • trial3  • average    • comparison   6 strains   age 10wks   Inbred Jaxpheno7 peak acceleration (0.1 rpm/s) on the rotarod prior to fall [s]         • trial1  • trial2  • trial3  • average    • comparison   6 strains   age 10wks   Inbred   behavior — involuntary movement         SHIRPA   Jaxpheno7 constant trembling in view-jar (score 0-2)   [score] 6 strains   age 10wks   Inbred Jaxpheno7 short sporadic twitches in view-jar (score 0-2)   [score] 6 strains   age 10wks   Inbred   behavior — locomotor activity         SHIRPA   Jaxpheno7 spontaneous activity level in view-jar (score 0-3)   [score] 6 strains   age 10wks   Inbred   behavior — wildness         SHIRPA   Jaxpheno7 aggressive behavior [score]         • provoked biting  • irritability  • aggression  • vocalization  • finger approach  6 strains   age 10wks   Inbred   muscle — skeletal — function         grip strength   Jaxpheno7 grip strength, peak tension [g]         • trial1  • trial2  • trial3  • average  • maximum    • comparison   6 strains   age 10wks   Inbred   nervous system — autonomic function         SHIRPA   Jaxpheno7 autonomic function [score]         • palpebral closing  • piloerection  • airpuff startle reflex        • trunk curl  • hindlimb grasp  • lacrimal reflex  • salivary reflex  6 strains   age 10wks   Inbred   nervous system — neuromuscular function         SHIRPA   Jaxpheno7 muscle function and fitness [score]         • gait  • positional passivity        • body tone  • limb tone  • abdominal tone  6 strains   age 10wks   Inbred   nervous system — sensorimotor function         SHIRPA   Jaxpheno7 motor responses to sensory stimulus [score]         • touch escape  • visual placing  • pinna reflex  • corneal reflex        • hindfoot withdrawal reflex  • cross extensor reflex  • wire grip maneuver        • righting reflex  • catalepsy  • negative geotaxis  6 strains   age 10wks   Inbred

Number of mice tested per strain, for each measurement