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Project data set: Hunter1   (1998)

Project Transgenic survey: Metastatic progression of a mammary tumor determined by genetic background of 28 inbred strains of mice

An investigation of primary mammary tumor latency, severity and metastasis. Subjects were transgene positive (MMTV-PyMT) F1 virgin female progeny of different inbred strains of mice. Primary tumors were noted and confirmed. Mice were analyzed 40 days later (aged to permit metastatic progression).

Study design: baseline survey; 1 cohort.
28 strains tested     female only     Test age: various

Investigators Hunter KW   [Details, papers]

Protocol View phenotyping protocol and methods

Hunter1
measurements



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          Ontologies


cancer — metastatic progression         histopathology  
Hunter1
mammary tumor latency, days after birth   [d]
28 strains  
  MMTV PyVT transgenic
Hunter1
tumor burden (body weight at sacrifice minus
body weight at diagnosis of primary tumor)
  [g]
28 strains  
  MMTV PyVT transgenic
Hunter1
number of pulmonary metastases  
      • number   • per total lung area (x 10-9) 
28 strains  
  MMTV PyVT transgenic
Hunter1
area of pulmonary metastases  
      • area (x 103  • per number of metastases   • per total lung area 
28 strains  
  MMTV PyVT transgenic
Hunter1
total lung area (x 103)   [µm2]
28 strains  
  MMTV PyVT transgenic



Number of mice tested per strain, for each measurement

  
Changelog There have been no updates or corrections to the data set since MPD release in May 2001  
Reference
Lifsted T, Le Voyer T, Williams M, Muller W, Klein-Szanto A, Buetow KH, Hunter KW. Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression. Int J Cancer. 1998 Aug 12;77(4):640-4.     PubMed 9679770     MGI

Related papers
Mice
Strain and animal info
Note
More information about the tested strains.
Note
Caution: Very low sample sizes (N < 3) are present. [View table]

Hunter1
downloads


Individual animal data
Table format (.csv)
Individual animal data in table format, with one row per animal and one column per measurement.
Individual animal data
List format (.csv)
Individual animal data organized as one row per animal / measurement reading.
Strain means (.csv) Strain means with SD, N, other summary statistics. One row per strain / sex / measurement.
No supplemental data for this project. 

 See also the MPD download center for more general data download options.





 




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