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C57BL/6J-Chr 15PWD/Ph/ForeJ
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C57BL/6J-Chr 15PWD/Ph/ForeJ
What Does This Nomenclature Mean?
Strain #:005265
RRID:IMSR_JAX:005265
Common Name: B6.PWD-Chr15Chromosome 15 from PWD/Ph has replaced the homologous chromosome of C57BL/6J in this strain of the set of consomic strains with C57BL/6J as background.
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Cryo-Recovered Mouse
Frozen Mouse Embryo#005265
Consomic
1 pair minimum
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Details
WHAT TO EXPECT
- A confirmation will be sent after order placement.
- Typically, eight or more animals are produced.
- The total number, sex and genotypes will be provided to you prior to scheduling shipment.
- Additional breeding may be required to produce the genotype(s) of interest
- If we fail to produce the animals of the correct genotype, you will not be charged, unless this is designated as "fee for service" project
How it's Made
Strain Highlights
Consomic
Originating Article When using the B6.PWD-Chr15 mouse strain in a publication, please cite the originating article(s) and include JAX stock #005265 in your Materials and Methods section.
When using the B6.PWD-Chr15 mouse strain in a publication, please cite the originating article(s) and include JAX stock #005265 in your Materials and Methods section.Detailed Description
This strain represents one of a panel of inter-species chromosome substitution (or consomic) strains (IC-ISS). Each strain carries a chromosome from the Mus musculus musculus wild-derived strain PWD/Ph introgressed into a Mus musculus domesticus C57BL/6J background. The two species are believed to have diverged 350,000 to one million years ago and exhibit multiple genetic and phenotypic differences. The strain set also includes a conplastic strain (mtPWD/Ph) created by sequential backcrossing of the donor female to the host male. A conplastic strain carries the mitochondrial genome of the donor strain. The IC-ISS strains represent a tool for dissection of quantitative trait loci.
Development
Dr. Jiri Forejt from The Institute of Molecular Genetics, Prague, Czech Republic developed the C57BL/6J-Chr #PWD/Ph/ForeJ strain set by replacing individual chromosomes from the PWD/Ph donor strain into the C57BL/6J host strain using a marker-assisted series of backcrosses. The set was donated to The Jackson Laboratory in 2005.
Genetics
Genetic Background
000664 C57BL/6J
000664 C57BL/6J
Generation
Generation Definitions >
F3p
(Last Updated: June 26th 2006)
Generation Definitions >
F3p
(Last Updated: June 26th 2006)
Husbandry
Genotyping Protocols
Genotyping Resources and Troubleshooting >
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Animal Health Reports
G200 (Maximum)Appearance
Coat Color
BlackDetails
black Related Genotype: a/a
Legal
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The Jackson Laboratory's Genotyping Promise
The Jackson Laboratory ensures the genetic quality and genotyping of JAX® Mice strains before making them available to researchers. However, phenotypes may vary due to environmental conditions and may not be fully characterized. Phenotype descriptions are based on published data, and JAX does not guarantee phenotype or breeding performance.
To ensure JAX® Mice meet your research needs, we recommend:
- Genotyping mutant mice upon arrival.
- Performing pilot experiments on a small number of mice.
- Ordering more than one breeding pair to establish your colony and avoid delays.