The BXH set of RI strains is used in the genetic analysis of numerous complex or potentially complex physiologic phenotypes including differences in thyroid function (Graves' disease), bone mineral density, atherosclerosis and leukemia. A SNP data set is available through the Mouse Phenome Database for the BXH strains. Another BXH genotype data set consists of 472 MIT CA-repeat dinucleotide microsatellite markers that were typed at UTHSC from 1998 through 2000. The file is taken directly from Williams and colleagues (2001) without any significant modification in genotypes. This order of markers has been updated to conform to the March 2005 assembly of the mouse genome (Build 34 or UCSC mm6). The data set may be downloaded from the University of Tennessee Gene Network site . A data set from Mouse Genome Informatics Contributed Data Sets is also available.

Tools for using the RI set are presented through the Mouse Phenome Database Specialized Strain Panel Query Form, and Gene Network.

This recombinant inbred strain was generated in the laboratory of Dr. Linda Siracusa from an initial cross of a C57BL/6J-Tyr^c-2J/Tyr^c-2J female by a C3H/HeJ male mouse followed by 16+ generations of brother-sister inbreeding. The mice arrived at The Jackson Laboratory in 2000 at generation F22.