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Product Type

Quantity

GenotypeInbred

Price

You Will Receive

1 pair minimum

Availability

Mice Available In 12 Weeks.Contact Customer Service for more information.

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Details

A confirmation will be sent after order placement.
Typically, eight or more animals are produced.
The total number, sex and genotypes will be provided to you prior to scheduling shipment.
Additional breeding may be required to produce the genotype(s) of interest
If we fail to produce the animals of the correct genotype, you will not be charged, unless this is designated as "fee for service" project

How it's Made

Recombinant Inbred (RI)

Originating Article

Browse References >

The BXD RI strains are used to study the genetics of behavioral phenotypes including alcohol and drug addiction, stress, and locomotor activity. The BXD set of RI strains also are used in the genetic analysis of numerous complex or potentially complex physiologic phenotypes including differences in organ weight and bone mineral density.

The strain distribution pattern (SDP) for the BXD RI strains is available through the Mouse Genome Informatics Contributed Data Sets and Gene Network. Additional tools and information are presented through the Mouse Phenome Database Specialized Strain Panel Query Form, and Gene Network .

Please note: BXD24TyRww/J (032926) has been inbred an additional 16 generations.

The BXD set of RI strains was developed in the laboratory of Benjamin Taylor and was transferred to The Jackson Laboratory from Dr. Taylor's research colony upon his retirement. Of 42 BXD RI strains originally derived from the C57BL/6J (Stock No. 000664) and DBA/2J (Stock No. 000671), a number have become extinct over the years. The other BXD RI strains now being distributed are listed under "Related Recombinant Inbred Strains."

In 2004, BXD24/TyJ developed a spontaneous mutation, rd16, and was renamed BXD24b/TyJ. This strain, formerly BXD24a, was cryo-recovered in 2004 from 1988 embryo stocks (F80) and does not exhibit retinal degeneration. In 2009, BXD24b was renamed BXD24/TyJ-Cep290^rd16/J (Stock No. 000031) to reflect the discovery of the genetic basis of the mutation. At the same time the "a" was dropped from this strain name.

Genetic Background
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Generation
Generation Definitions >
[F84p+4]
(Last Updated: April 19th 2005)

Allele Symbol B2m^a

Allele Name

Gene Symbol

Allele Type

Gene Name

Gene Synonym(s)

Site of Expression

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Expressed Gene(s)

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Strain of Origin

Chromosome

Molecular Note

The a variant is slightly slower running on SDS PAGE and was found to have an aspartic acid at amino acid position 85. This allele is found in A, BALB/c, LP and most other strains.

General Note

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Mutations Made By

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Legal

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Licensing Information

Phone: 207-288-6470

Email: TechTran@jax.org

Terms are granted by individual review and stated on the customer invoice(s) and account statement. These transactions are payable in U.S. currency within the granted terms. Payment for services, products, shipping containers, and shipping costs that are rendered are expected within the payment terms indicated on the invoice or stated by contract. Invoices and account balances in arrears of stated terms may result in The Jackson Laboratory pursuing collection activities including but not limited to outside agencies and court filings.

The Jackson Laboratory ensures the genetic quality and genotyping of JAX® Mice strains before making them available to researchers. However, phenotypes may vary due to environmental conditions and may not be fully characterized. Phenotype descriptions are based on published data, and JAX does not guarantee phenotype or breeding performance.

To ensure JAX® Mice meet your research needs, we recommend:

Genotyping mutant mice upon arrival.
Performing pilot experiments on a small number of mice.
Ordering more than one breeding pair to establish your colony and avoid delays.

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