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BXD6/TyJ
- Overview
- How it's Made
- How it's Used
- Husbandry
- Legal
- Related Strains
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BXD6/TyJ
What Does This Nomenclature Mean?
Strain #:000007
RRID:IMSR_JAX:000007
The BXD set of RI strains is used in the genetic analysis of numerous complex or potentially complex physiologic phenotypes. The BXD strains are derived from the C57BL/6J (Stock No. 000664) and DBA/2J (Stock No. 000671) progenitor strains.
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Cryo-Recovered Mouse#000007
Inbred
1 pair minimum
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Details
WHAT TO EXPECT
- A confirmation will be sent after order placement.
- Typically, eight or more animals are produced.
- The total number, sex and genotypes will be provided to you prior to scheduling shipment.
- Additional breeding may be required to produce the genotype(s) of interest
- If we fail to produce the animals of the correct genotype, you will not be charged, unless this is designated as "fee for service" project
How it's Made
Strain Highlights
Recombinant Inbred (RI)
Originating Article When using the BXD6/TyJ mouse strain in a publication, please cite the originating article(s) and include JAX stock #000007 in your Materials and Methods section.
When using the BXD6/TyJ mouse strain in a publication, please cite the originating article(s) and include JAX stock #000007 in your Materials and Methods section.Detailed Description
The BXD RI strains are used to study the genetics of behavioral phenotypes including alcohol and drug addiction, stress, and locomotor activity. The BXD set of RI strains also is used in the genetic analysis of numerous complex or potentially complex physiologic phenotypes including differences in organ weight and bone mineral density.
The strain distribution pattern (SDP) for the BXD RI strains is available through the Mouse Genome Informatics Contributed Data Sets and Gene Network. Additional tools and information are presented through the Mouse Phenome Database Specialized Strain Panel Query Form, and Gene Network.
The Jackson Laboratory live colony was a challenging breeder / very poor breeder. It exhibited a high incidence of non-productive matings and when productive, the litters were small [May 2021]. See our General Husbandry Tips.
Development
The BXD set of RI strains was developed in the laboratory of Benjamin Taylor and was transferred to The Jackson Laboratory from Dr. Taylor's research colony upon his retirement. Of 42 BXD RI strains originally derived from the C57BL/6J (Stock No. 000664) and DBA/2J (Stock No. 000671), a number have become extinct over the years. The other BXD RI strains now being distributed are listed under "Related Recombinant Inbred Strains."
Genetics
Genetic Background
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Generation
Generation Definitions >
[F40p]
(Last Updated: June 10th 2002)
Generation Definitions >
[F40p]
(Last Updated: June 10th 2002)