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How it's Made

Strain Highlights
Strain Type
Recombinant Inbred (RI)
Originating Article
Originating Article
Info When using the BXD25/TyJ mouse strain in a publication, please cite the originating article(s) and include JAX stock #000081 in your Materials and Methods section.

Detailed Description
The BXD RI strains are used to study the genetics of behavioral phenotypes including alcohol and drug addiction, stress, and locomotor activity. The BXD set of RI strains also are used in the genetic analysis of numerous complex or potentially complex physiologic phenotypes including differences in organ weight and bone mineral density.

The strain distribution pattern (SDP) for the BXD RI strains is available through the Mouse Genome Informatics Contributed Data Sets and Gene Network. Additional tools and information are presented through the Mouse Phenome Database Specialized Strain Panel Query Form, and Gene Network .


Development
The BXD set of RI strains was developed in the laboratory of Benjamin Taylor and was transferred to The Jackson Laboratory from Dr. Taylor's research colony upon his retirement. Of 42 BXD RI strains originally derived from the C57BL/6J (Stock No. 000664) and DBA/2J (Stock No. 000671), a number have become extinct over the years. The other BXD RI strains now being distributed are listed under "Related Recombinant Inbred Strains."

Genetics
Genetic Background
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Generation
Generation Definitions >
F33p+F1p
(Last Updated: January 25th 2007)
Allele Symbol Myo5ad ExternalLink
Allele Name
dilute
Gene Symbol
Myo5a
Allele Type
Spontaneous
Gene Name
myosin VA
Gene Synonym(s)
9630007J19Rik,Dbv,Dop, ... 9630007J19Rik, Dbv, Dop, flail, GS1, MVa, Myh12, MYO5, MyoVA, MYR12, nmf244,
Site of Expression
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Expressed Gene(s)
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Strain of Origin
old mutant of the mouse fancy
Chromosome
9
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