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BXD2/TyJ
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BXD2/TyJ
What Does This Nomenclature Mean?
Strain #:000075
RRID:IMSR_JAX:000075
The BXD set of RI strains is used in the genetic analysis of numerous complex or potentially complex physiologic phenotypes. The BXD2/TyJ strain develops spontaneous arthritis in 50% of females by 8 months of age and 90% of males greater than 12 months of age. Adult mice exhibit glomerulonephritis, proteinuria (by 6 months), splenomegaly, and autoantibody production. The BXD strains are derived from the C57BL/6J (Stock No. 000664) and DBA/2J (Stock No. 000671) progenitor strains.
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