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CXB11/HiAJ
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CXB11/HiAJ
What Does This Nomenclature Mean?
Strain #:001632
RRID:IMSR_JAX:001632
The CXB set of RI strains is used in the genetic analysis of numerous complex or potentially complex physiologic phenotypes including differences in thyroid function (Graves' disease) and pulmonary inflammation as well as behavioral phenotypes including avoidance, exploration and locomotor activity. The CXB set is derived from the BALBc/ByJ (Stock No. 001026) and C57BL/6ByJ (Stock No. 001139) progenitor strains.
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How it's Made
Strain Highlights
Recombinant Inbred (RI)
Originating Article When using the CXB11/HiAJ mouse strain in a publication, please cite the originating article(s) and include JAX stock #001632 in your Materials and Methods section.
When using the CXB11/HiAJ mouse strain in a publication, please cite the originating article(s) and include JAX stock #001632 in your Materials and Methods section.Detailed Description
The CXB set of RI strains is used in the genetic analysis of numerous complex or potentially complex physiologic phenotypes including differences in thyroid function (Graves' disease) and pulmonary inflammation as well as behavioral phenotypes including avoidance, exploration and locomotor activity.
The CXB set is so small that markers on different chromosomes occasionally have almost precisely the same SDP. This produces high non-syntenic association and false linkage between variance in phenotypes and genotypes. Please examine the correlation coefficients of markers close to interest loci with ALL other markers to evaluate the risk of non-syntenic association.
The strain distribution pattern (SDP) for the CXB RI strains is available through the Mouse Genome Informatics Contributed Data Sets and Gene Network. Additional tools and information are presented through the Mouse Phenome Database Specialized Strain Panel Query Form, and Gene Network.
Genetics
Genetic Background
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Generation
Generation Definitions >
F45
(Last Updated: August 28th 1998)
Generation Definitions >
F45
(Last Updated: August 28th 1998)
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The Jackson Laboratory's Genotyping Promise
The Jackson Laboratory ensures the genetic quality and genotyping of JAX® Mice strains before making them available to researchers. However, phenotypes may vary due to environmental conditions and may not be fully characterized. Phenotype descriptions are based on published data, and JAX does not guarantee phenotype or breeding performance.
To ensure JAX® Mice meet your research needs, we recommend:
- Genotyping mutant mice upon arrival.
- Performing pilot experiments on a small number of mice.
- Ordering more than one breeding pair to establish your colony and avoid delays.