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AXB15/PgnJ
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AXB15/PgnJ
What Does This Nomenclature Mean?
Strain #:001685
RRID:IMSR_JAX:001685
The AXB and BXA set of RI strains are useful in the genetic analysis of complex diseases. The individual strains within the RI set also differ in their susceptibility to infectious diseases and in their responses to alcohol, stress, and endotoxin. AXB and BXA strains are derived from the C57BL/6J (Stock No. 000664) and A/J (Stock No. 000646) progenitor strains.
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How it's Made
Strain Highlights
Recombinant Inbred (RI)
Originating Article When using the AXB15/PgnJ mouse strain in a publication, please cite the originating article(s) and include JAX stock #001685 in your Materials and Methods section.
When using the AXB15/PgnJ mouse strain in a publication, please cite the originating article(s) and include JAX stock #001685 in your Materials and Methods section.Detailed Description
The AXB and BXA set of RI strains are useful in the genetic analysis of several complex diseases including cardiovascular disease, diabetes, cancer, cleft palate, and hydrocephalus. The individual strains within the RI set also differ in their susceptibility to infectious diseases and in their responses to alcohol, stress, and endotoxin.
The strain distribution pattern (SDP) for the AXB RI strains is available through the Mouse Genome Informatics Contributed Data Sets and Gene Network. Additional tools and information are presented through the Mouse Phenome Database Specialized Strain Panel Query Form, and Gene Network .
Development
The AXB and BXA recombinant inbred (RI) set of strains were originally generated and maintained at the University of California, San Diego, and have been imported into The Jackson Laboratory. There were originally 51 AXB and BXA strains derived from the C57BL/6J (Stock No. 000664) and A/J (Stock No. 000646) progenitor strains. Many of the original strains are either extinct or were discarded due to genetic contamination. Please refer to Sampson et al., 1998 for more information.
Genetics
Genetic Background
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Generation
Generation Definitions >
[F38p]
(Last Updated: December 2nd 1991)
Generation Definitions >
[F38p]
(Last Updated: December 2nd 1991)
Legal
Terms of Use
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The Jackson Laboratory's Genotyping Promise
The Jackson Laboratory ensures the genetic quality and genotyping of JAX® Mice strains before making them available to researchers. However, phenotypes may vary due to environmental conditions and may not be fully characterized. Phenotype descriptions are based on published data, and JAX does not guarantee phenotype or breeding performance.
To ensure JAX® Mice meet your research needs, we recommend:
- Genotyping mutant mice upon arrival.
- Performing pilot experiments on a small number of mice.
- Ordering more than one breeding pair to establish your colony and avoid delays.