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B6SJLF1/J
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B6SJLF1/J
What Does This Nomenclature Mean?
Strain #:100012
RRID:IMSR_JAX:100012
Produced by a cross between a C57BL/6J (B6) female x an SJL/J (SJL) male. B6SJLF1/J mice are heterozygous for B6 and SJL alleles at all loci in their genome. This strain is often used in the production of transgenic mice.
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How it's Made
Strain Highlights
F1 or F2 Hybrid
Originating Article When using the B6SJLF1/J mouse strain in a publication, please cite the originating article(s) and include JAX stock #100012 in your Materials and Methods section.
When using the B6SJLF1/J mouse strain in a publication, please cite the originating article(s) and include JAX stock #100012 in your Materials and Methods section.Detailed Description
These F1 (first filial generation) hybrid mice are the offspring of a cross between C57BL/6J females (B6) and SJL/J males (SJL). F1 hybrid mice are heterozygous at all loci (assuming the parental strains have different alleles), and like inbred mice they are genetically and phenotypically uniform. F1 hybrids are often used for hybrid vigor, as a background for some deleterious mutations, for tissue transplantation, to determine the mode of inheritance, to create or enhance expression of polygenic diseases, and to provide physiological buffering (present a broader array of responses to various stresses).
Development
These F1 (first filial generation) hybrid mice are the offspring of a cross between C57BL/6J females (B6) and SJL/J males (SJL).
Genetics
Genetic Background
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Generation
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How it's Used
References
When using the B6SJLF1/J mouse strain in a publication, please cite the originating article(s) and include JAX stock #100012 in your Materials and Methods section.
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EM08 (Maximum)Appearance
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agoutiRelated Genotype: A/a p Tyrc/+ + Pde6brd1/+
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The Jackson Laboratory's Genotyping Promise
The Jackson Laboratory ensures the genetic quality and genotyping of JAX® Mice strains before making them available to researchers. However, phenotypes may vary due to environmental conditions and may not be fully characterized. Phenotype descriptions are based on published data, and JAX does not guarantee phenotype or breeding performance.
To ensure JAX® Mice meet your research needs, we recommend:
- Genotyping mutant mice upon arrival.
- Performing pilot experiments on a small number of mice.
- Ordering more than one breeding pair to establish your colony and avoid delays.