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SOD1/EiJ
- Overview
- How it's Made
- How it's Used
- Husbandry
- Legal
- Related Strains
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How it's Made
Strain Highlights
Inbred Strain
Originating Article
When using the SOD1/EiJ mouse strain in a publication, please include JAX stock #001224 in your Materials and Methods section.
When using the SOD1/EiJ mouse strain in a publication, please include JAX stock #001224 in your Materials and Methods section.Detailed Description
SOD1/EiJ carries a spontaneous mutation in the Sod1 gene (Luche et al., 1997). The mutation differs from the C57BL/6J sequence at position 231 and changes a glutamate to a lysine in a positively charged amino acid domain within the Zn-subloop. This strain is fertile and exhibits no obvious phenotype.
Development
Although there is little information on the history of this strain, our records suggest that this stock carries a slow migrating protein variant of SOD1 derived from a wild-caught Mus domesticus female (caught in Greece) and was crossed at least one generation to C57BL/6J. The Jackson Laboratory maintains this colony as an inbred strain (sibling mating).
Genetics
Genetic Background
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Generation
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Legal
Terms of Use
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Licensing Information
Phone: 207-288-6470
Email: TechTran@jax.org
Payment Terms and Conditions
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The Jackson Laboratory's Genotyping Promise
The Jackson Laboratory ensures the genetic quality and genotyping of JAX® Mice strains before making them available to researchers. However, phenotypes may vary due to environmental conditions and may not be fully characterized. Phenotype descriptions are based on published data, and JAX does not guarantee phenotype or breeding performance.
To ensure JAX® Mice meet your research needs, we recommend:
- Genotyping mutant mice upon arrival.
- Performing pilot experiments on a small number of mice.
- Ordering more than one breeding pair to establish your colony and avoid delays.