MPD: Project measures / variables set: Rhodes1 DG

Project measures / variables set: Rhodes1 DG_neurons

ID, description, units	MPD:34605 DG_neurons hippocampus: number of new neurons in dentate gyrus [n] exercise study
Measures	• control • with running wheel
Data set, strains	Rhodes1 inbred 12 strains sex: both age: 15wks
Procedure	microscopy
Comparison	control group vs. treated group
Ontology mappings	VT:0000812 dentate gyrus morphology trait VT:0006008 neurogenesis trait VT:0015026 neuron quantity VT:1000152 wellness/fitness trait MA:0000946 dentate gyrus granule cell layer MP:0000812 abnormal dentate gyrus morphology MP:0012735 abnormal response to exercise

Values Means Δ Means Z-scores

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Rhodes1 - hippocampus: number of new neurons in dentate gyrus

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	618111948.0	618111948.0	234.735	< 0.0001
group:sex	1	47732.9068	47732.9068	0.0181	0.8931
group:sex:strain	11	33743063.4775	3067551.2252	1.1649	0.3165
group:strain	11	81387823.6931	7398893.063	2.8098	0.0024
Residuals	144	379185559.4167	2633233.0515
sex	1	108090.0413	108090.0413	0.041	0.8397
sex:strain	11	34044177.8488	3094925.259	1.1753	0.3092
strain	11	164837816.2824	14985256.0257	5.6908	< 0.0001

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Rhodes1	34605	microscopy	exercise	hippocampus: number of new neurons in dentate gyrus [n] control DG_neurons_control	inbred	12	both	15wks
Rhodes1	34606	microscopy	exercise	hippocampus: number of new neurons in dentate gyrus [n] with running wheel DG_neurons_wheel	inbred	12	both	15wks