Phenotype measure:   Schughart3   pctbwB_d4

ID, description, units MPD:57134   pctbwB_d4   body weight as percent of baseline, 2000 FFU group   [%]  post-infection day 4   measure
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   8 strains     sex: both     age: 7-13wks
Procedure body weight
Ontology mappings

  STRAIN COMPARISON PLOT
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Schughart3 - body weight as percent of baseline, 2000 FFU group post-infection day 4



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means80.5   % 81.5   %
Median of the strain means77.2   % 78.5   %
SD of the strain means± 7.07 ± 6.64
Coefficient of variation (CV)0.0878 0.0815
Min–max range of strain means75.0   –   94.1   % 75.1   –   94.1   %
Mean sample size per strain8.6   mice 9.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 17.0395 17.0395 1.1039 0.2954
strain 7 6203.8042 886.2577 57.4165 < 0.0001
sex:strain 7 63.2955 9.0422 0.5858 0.7665
Residuals 128 1975.7551 15.4356


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 81.1 6.91   10 2.18 0.0852 75.8, 99.4 0.08
129S1/SvImJ m 82.2 4.28   10 1.35 0.052 77.1, 91.4 0.1
A/J f 75.0 2.32   6 0.945 0.0309 72.0, 79.1 -0.78
A/J m 76.7 1.51   6 0.615 0.0196 74.9, 79.3 -0.73
C57BL/6J f 75.5 1.63   11 0.493 0.0216 72.5, 78.2 -0.71
C57BL/6J m 78.1 3.01   10 0.951 0.0385 73.8, 83.2 -0.52
CAST/EiJ f 76.5 2.41   8 0.852 0.0315 70.9, 78.3 -0.57
CAST/EiJ m 75.1 3.01   12 0.869 0.0401 70.9, 79.3 -0.97
NOD/ShiLtJ f 77.8 3.11   10 0.984 0.04 72.7, 83.2 -0.39
NOD/ShiLtJ m 78.1 3.11   9 1.04 0.0398 74.2, 83.8 -0.52
NZO/HlLtJ f 94.1 3.51   9 1.17 0.0373 86.2, 98.9 1.92
NZO/HlLtJ m 94.1 5.09   11 1.54 0.0541 80.2, 98.8 1.89
PWK/PhJ f 88.5 4.93   11 1.49 0.0558 82.2, 97.5 1.13
PWK/PhJ m 89.0 5.17   10 1.63 0.058 83.9, 99.5 1.12
WSB/EiJ f 75.8 1.22   4 0.612 0.0161 74.4, 77.4 -0.67
WSB/EiJ m 79.0 3.75   7 1.42 0.0475 74.9, 84.9 -0.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 81.085 1.2424 83.5433 78.6267
129S1/SvImJ m 82.21 1.2424 84.6683 79.7517
A/J f 75.0483 1.6039 78.222 71.8747
A/J m 76.66 1.6039 79.8337 73.4863
C57BL/6J f 75.5173 1.1846 77.8612 73.1734
C57BL/6J m 78.123 1.2424 80.5813 75.6647
CAST/EiJ f 76.5425 1.389 79.291 73.794
CAST/EiJ m 75.0858 1.1342 77.3299 72.8417
NOD/ShiLtJ f 77.785 1.2424 80.2433 75.3267
NOD/ShiLtJ m 78.1167 1.3096 80.7079 75.5254
NZO/HlLtJ f 94.1456 1.3096 96.7368 91.5543
NZO/HlLtJ m 94.0718 1.1846 96.4157 91.7279
PWK/PhJ f 88.4718 1.1846 90.8157 86.1279
PWK/PhJ m 88.998 1.2424 91.4563 86.5397
WSB/EiJ f 75.8075 1.9644 79.6944 71.9206
WSB/EiJ m 78.9586 1.485 81.8968 76.0203


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 81.6475 0.8785 83.3858 79.9092
A/J both 75.8542 1.1342 78.0983 73.6101
C57BL/6J both 76.8201 0.8583 78.5185 75.1218
CAST/EiJ both 75.8142 0.8966 77.5883 74.04
NOD/ShiLtJ both 77.9508 0.9026 79.7367 76.1649
NZO/HlLtJ both 94.1087 0.8829 95.8557 92.3616
PWK/PhJ both 88.7349 0.8583 90.4332 87.0366
WSB/EiJ both 77.383 1.2313 79.8193 74.9468




GWAS analysis not available: At least 12 strains are required