Project measure / variable:   Schoonjans1   DCA_plasma_t30_HFD

ID, description, units MPD:112695   DCA_plasma_t30_HFD   plasma bile acid deoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid deoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means39.705   ng/mL
Median of the strain means28.723   ng/mL
SD of the strain means± 28.175
Coefficient of variation (CV)0.7096
Min–max range of strain means8.632   –   110.7   ng/mL
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 120785.6329 3552.5186 3.0875 < 0.0001
Residuals 117 134619.8671 1150.5972


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 89.65 49.407   5 22.096 0.5511 18.136, 128.3 1.77
BXD100 m 16.232 23.178   9 7.7259 1.4279 2.596, 74.74 -0.83
BXD11 m 8.632 0.0   1   0.0 0.0 8.632, 8.632 -1.1
BXD12 m 51.2 61.0   4 30.501 1.1914 9.544, 141.3 0.41
BXD27 m 40.07 28.009   5 12.526 0.699 15.562, 80.91 0.01
BXD32 m 21.901 8.242   4 4.121 0.3763 9.906, 27.852 -0.63
BXD34 m 12.541 6.5974   4 3.2987 0.5261 6.082, 20.154 -0.96
BXD39 m 40.681 55.38   3 31.974 1.3613 7.066, 104.6 0.03
BXD40 m 11.775 5.6605   4 2.8303 0.4807 4.784, 16.986 -0.99
BXD43 m 15.006 6.7485   5 3.018 0.4497 3.626, 21.674 -0.88
BXD45 m 25.78 6.9869   5 3.1246 0.271 18.462, 35.748 -0.49
BXD48 m 29.756 15.174   5 6.786 0.51 12.622, 48.73 -0.35
BXD48a m 69.5 24.903   4 12.451 0.3583 38.054, 93.78 1.06
BXD49 m 47.718 34.279   5 15.33 0.7184 21.656, 103.4 0.28
BXD51 m 33.359 19.156   3 11.06 0.5742 11.268, 45.375 -0.23
BXD53 m 36.571 10.125   5 4.5281 0.2769 21.066, 46.89 -0.11
BXD55 m 24.771 6.4331   5 2.877 0.2597 17.252, 32.936 -0.53
BXD6 m 25.204 13.401   3 7.7368 0.5317 11.23, 37.946 -0.51
BXD62 m 53.37 26.684   4 13.342 0.5 22.738, 87.81 0.49
BXD63 m 96.87 48.682   5 21.771 0.5025 48.41, 162.6 2.03
BXD64 m 15.047 8.8954   5 3.9782 0.5912 6.668, 27.848 -0.88
BXD66 m 12.851 4.195   3 2.422 0.3264 8.644, 17.034 -0.95
BXD67 m 27.69 13.564   5 6.0661 0.4899 19.022, 51.36 -0.43
BXD69 m 110.7 93.31   4 46.657 0.8429 8.866, 229.7 2.52
BXD73 m 21.527 5.5539   3 3.2066 0.258 16.91, 27.69 -0.65
BXD75 m 65.66 37.456   4 18.728 0.5704 33.45, 117.2 0.92
BXD77 m 18.715 6.5849   5 2.9448 0.3518 13.182, 29.426 -0.74
BXD79 m 63.39 25.179   5 11.261 0.3972 36.264, 102.7 0.84
BXD8 m 11.886 3.0123   2   2.13 0.2534 9.756, 14.016 -0.99
BXD81 m 85.5 21.956   5 9.8192 0.2568 58.06, 119.0 1.63
BXD84 m 96.41 100.2   5 44.795 1.039 24.312, 272.1 2.01
BXD87 m 40.224 12.914   4 6.457 0.3211 27.804, 55.67 0.02
BXD89 m 16.188 11.172   5 4.9965 0.6902 10.014, 36.134 -0.83
BXD90 m 24.611 14.766   4 7.3829 0.6 7.7588, 39.66 -0.54
C57BL/6J m 50.99 16.112   3 9.3022 0.316 32.51, 62.09 0.4
DBA/2J m 17.391 7.5748   3 4.3733 0.4356 9.7, 24.844 -0.79


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 89.6532 15.1696879007 119.6959719758 59.6104280242
BXD100 m 16.2315555556 11.3068177812 38.624115679 -6.1610045679
BXD12 m 51.2035 16.9602266717 84.7923401852 17.6146598148
BXD27 m 40.07 15.1696879007 70.1127719758 10.0272280242
BXD32 m 21.901 16.9602266717 55.4898401852 -11.6878401852
BXD34 m 12.541 16.9602266717 46.1298401852 -21.0478401852
BXD39 m 40.6806666667 19.5839828689 79.465718512 1.8956148213
BXD40 m 11.7755 16.9602266717 45.3643401852 -21.8133401852
BXD43 m 15.0064 15.1696879007 45.0491719758 -15.0363719758
BXD45 m 25.7796 15.1696879007 55.8223719758 -4.2631719758
BXD48 m 29.7556 15.1696879007 59.7983719758 -0.2871719758
BXD48a m 69.5035 16.9602266717 103.0923401852 35.9146598148
BXD49 m 47.7184 15.1696879007 77.7611719758 17.6756280242
BXD51 m 33.359 19.5839828689 72.1440518454 -5.4260518454
BXD53 m 36.5708 15.1696879007 66.6135719758 6.5280280242
BXD55 m 24.7712 15.1696879007 54.8139719758 -5.2715719758
BXD6 m 25.2043333333 19.5839828689 63.9893851787 -13.580718512
BXD62 m 53.3685 16.9602266717 86.9573401852 19.7796598148
BXD63 m 96.872 15.1696879007 126.9147719758 66.8292280242
BXD64 m 15.0472 15.1696879007 45.0899719758 -14.9955719758
BXD66 m 12.8506666667 19.5839828689 51.635718512 -25.9343851787
BXD67 m 27.6904 15.1696879007 57.7331719758 -2.3523719758
BXD69 m 110.704 16.9602266717 144.2928401852 77.1151598148
BXD73 m 21.5266666667 19.5839828689 60.311718512 -17.2583851787
BXD75 m 65.662 16.9602266717 99.2508401852 32.0731598148
BXD77 m 18.7152 15.1696879007 48.7579719758 -11.3275719758
BXD79 m 63.3868 15.1696879007 93.4295719758 33.3440280242
BXD8 m 11.886 23.9853825801 59.3877933343 -35.6157933343
BXD81 m 85.496 15.1696879007 115.5387719758 55.4532280242
BXD84 m 96.4104 15.1696879007 126.4531719758 66.3676280242
BXD87 m 40.224 16.9602266717 73.8128401852 6.6351598148
BXD89 m 16.1876 15.1696879007 46.2303719758 -13.8551719758
BXD90 m 24.6107 16.9602266717 58.1995401852 -8.9781401852
C57BL/6J m 50.99 19.5839828689 89.7750518454 12.2049481546
DBA/2J m 17.3906666667 19.5839828689 56.175718512 -21.3943851787




  GWAS USING LINEAR MIXED MODELS