Intervention:   influenza A (H3N2) virus          

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Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg) Year
    Schughart3 57111 body weight influenza A (H3N2) virus body weight as percent of baseline, 10 FFU group   [%]     days post-infection:    1    2    3    4    5    6    7    8    9    10    11    12    13    14 inbred w/CC8 8 both 7-13wks N=9 2013
    Schughart3 57131 body weight influenza A (H3N2) virus body weight as percent of baseline, 2000 FFU group   [%]     days post-infection:    1    2    3    4    5    6    7    8    9    10    11    12    13    14 inbred w/CC8 8 both 7-13wks N=9 2013
    Schughart3 57151 body weight influenza A (H3N2) virus body weight as percent of baseline, 200,000 FFU group   [%]     days post-infection:    1    2    3    4    5    6    7    8    9    10    11    12    13    14 inbred 2 both 7-13wks N=12 2013
    Schughart3 57181 health assessment influenza A (H3N2) virus survival, post-infection   [d]     10 FFU group    2000 FFU group    200000 FFU group inbred w/CC8 8 both 7-13wks N=11 2013
    Schughart3 57191 health assessment influenza A (H3N2) virus susceptibility to viral infection (0=resistant, 1=susceptible), mortality rate   [score]     10 FFU group    2000 FFU group    200000 FFU group inbred w/CC8 8 both 7-13wks N=11 2013
    Schughart4 58721 body weight influenza A (H3N2) virus body weight as percent of baseline, infected group   [%]     days post-infection:    1    2    3    4    5    6    7    8    9    10    11    12    13    14    18    30 inbred w/CC8 8 f 8-12wks N=11 2016
    Schughart4 58741 complete blood count influenza A (H3N2) virus white blood cell count (WBC; per volume x 103), control group, day 3   [n/µL]  WBC_ctrl_d3 inbred w/CC8 8 f 8-12wks N=5 2016
    Schughart4 58743 complete blood count influenza A (H3N2) virus white blood cell count (WBC), treated group   [n/µL]     days post-infection:    3    5    8    18    30 inbred w/CC8 8 f 8-12wks N=6 2016
    Schughart4 58751 complete blood count influenza A (H3N2) virus lymphocyte differential (percent of total WBC), control group, day 3   [%]  pctLYM_ctrl_d3 inbred w/CC8 8 f 8-12wks N=5 2016
    Schughart4 58753 complete blood count influenza A (H3N2) virus lymphocyte differential, treated group   [%]     days post-infection:    3    5    8    18    30 inbred w/CC8 8 f 8-12wks N=6 2016
    Schughart4 58761 complete blood count influenza A (H3N2) virus monocyte differential (percent of total WBC), control group, day 3   [%]  pctMONO_ctrl_d3 inbred w/CC8 8 f 8-12wks N=5 2016
    Schughart4 58763 complete blood count influenza A (H3N2) virus monocyte differential, treated group   [%]     days post-infection:    3    5    8    18    30 inbred w/CC8 8 f 8-12wks N=6 2016
    Schughart4 58771 complete blood count influenza A (H3N2) virus granulocyte differential (percent of total WBC), control group, day 3   [%]  pctGRA_ctrl_d3 inbred w/CC8 8 f 8-12wks N=5 2016
    Schughart4 58773 complete blood count influenza A (H3N2) virus granulocyte differential, treated group   [%]     days post-infection:    3    5    8    18    30 inbred w/CC8 8 f 8-12wks N=6 2016
    Schughart4 58783 in vitro assay influenza A (H3N2) virus viral load in lungs (titer, FFU per lung) log10 (x+1)   [log(n)]     days post-infection:    3    5    8 inbred w/CC8 8 f 8-12wks N=5 2016
    Schughart5 58821 body weight influenza A (H3N2) virus body weight as percent of baseline, 10 FFU group   [%]     days post-infection:    1    2    3    4    5    6    7    8    9    10    11    12    13    14    18    30 inbred w/CC8 8 f 8-12wks N=9 2016
    Schughart5 58881 organ weights influenza A (H3N2) virus lung weight, control group, day 3   [g]  lungwt_ctrl_d3 inbred w/CC8 8 f 10wks N=3 2016
    Schughart5 58883 organ weights influenza A (H3N2) virus lung weight, treated group   [g]     days post-infection:    3    5    8    18    30 inbred w/CC8 8 f 10wks N=4 2016
    Schughart5 58891 organ weights influenza A (H3N2) virus relative lung weight, control group, day 3   [%]  lungwtadj_ctrl_d3 inbred w/CC8 8 f 10wks N=3 2016
    Schughart5 58893 organ weights influenza A (H3N2) virus relative lung weight, treated group   [%]     days post-infection:    3    5    8    18    30 inbred w/CC8 8 f 10wks N=4 2016
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