Alcohol withdrawal severity. One group of mice was exposed to ethanol (EtOH) vapor in an inhalation chamber while the control group was not exposed to EtOH (air only). The investigators note that they consider the most important measurement in the study to be: "withdrawal severity during 0-25h (area under curve of HIC scores), aerolized EtOH normalized to controls" (see below).

Available measurements   Mice & strains       Protocol       Plots & tools wizard Change list style       Show varnames       Verbose listing       Display strain data     Compare 2 strains behavior — activity and motor function — handling-induced convulsion   Metten2 peak handling-induced convulsion score [score]     control and  EtOH aerosolized       • control        • aerosolized EtOH        • aerosolized EtOH normalized to controls        15 strains   age 8-15wks Metten2 latency to first score used to calculate peak EtOH   [h]   EtOH   aerosolized 15 strains   age 8-15wks Metten2 withdrawal severity during 0-25 h (area under curve of HIC scores) [unit2]   EtOH   aerosolized       • aerolized EtOH        • aerolized EtOH normalized to controls        15 strains   age 8-15wks   body weight   Metten2 body weight [g]         • start        • Δchange after testing        15 strains   age 8-15wks Display strain means in the above table for: select a strain 129S1/SvImJ AKR/J BALB/cByJ BTBR T+ tf/J C3H/HeJ C57BL/6J C57BR/cdJ C57L/J CBA/J CE/J DBA/1J DBA/2J FVB/NJ PL/J SJL/J   Compare two strains: select strain 1 129S1/SvImJ AKR/J BALB/cByJ BTBR T+ tf/J C3H/HeJ C57BL/6J C57BR/cdJ C57L/J CBA/J CE/J DBA/1J DBA/2J FVB/NJ PL/J SJL/J vs. select strain 2 129S1/SvImJ AKR/J BALB/cByJ BTBR T+ tf/J C3H/HeJ C57BL/6J C57BR/cdJ C57L/J CBA/J CE/J DBA/1J DBA/2J FVB/NJ PL/J SJL/J   Compare female vs. male for: select a strain 129S1/SvImJ AKR/J BALB/cByJ BTBR T+ tf/J C3H/HeJ C57BL/6J C57BR/cdJ C57L/J CBA/J CE/J DBA/1J DBA/2J FVB/NJ PL/J SJL/J   Display overall measurement averages (all strains combined) in the above table

Notes

Metten P, Crabbe JC. Alcohol withdrawal severity in inbred mouse (Mus musculus) strains. Behav Neurosci. 2005 Aug;119(4):911-25.     PubMed    MGI There have been no updates or corrections to the dataset since it was first released in Jan, 2007 Some strain means have N < 5 animals (click for table). Some measurements were derived by MPD staff, based on supplied data (click for list).

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The Metten2 project data set. Individual animal data in table format, with one row per animal and measurements organized as columns. Excel file Metten2 individual animal data in list format. Most or all of the same information* as the file above, but organized as one row per animal / measurement. Excel file Metten2 strain means, SD, SEM, N, Z-scores and other summary statistics. One row per strain / sex / measurement. Excel file These Excel files include data, descriptions, and units for all measurements listed above. Other download options are available via the Plots & Tools Wizard, above. Metten2 protocol document HTML Metten2 animal documentation HTML Supplemental data are available Click here for more info