Diet effects on bone mineral density and content, body composition, and plasma glucose, leptin, and insulin levels.

Available measurements   Mice & strains       Protocol       Plots & tools wizard Change list style       Show varnames       Verbose listing       Display strain data     Compare 2 strains blood chemistry — glucose   Naggert1 glucose (plasma GLU, 4h fast) [mg/dL]     baseline and  high-fat diet 17wks       • baseline        • after 17wks on diet        • Δchange after diet          diet effect comparison   43 strains   age 7-9wks                 at baseline   body composition — fat — (head excluded)   Naggert1 fat portion of tissue mass   high-fat diet   8wks       • fat weight [g]        • % fat        43 strains   age 15-17wks   body composition — lean — (head excluded)   Naggert1 weight of lean portion of tissue mass   [g]   high-fat diet   8wks 43 strains   age 15-17wks   body composition — total — (head excluded)   Naggert1 total tissue mass   [g]   high-fat diet   8wks 43 strains   age 15-17wks   body weight   Naggert1 body weight   [g]   high-fat diet   8wks 43 strains   age 15-17wks   bone — mineral density and content — whole body (head excluded)   Naggert1 BMD and BMC   high-fat diet   8wks       • BMD        • BMC        43 strains   age 15-17wks   endocrine — hormones   Naggert1 leptin   [pg/mL]   high-fat diet   18wks 43 strains   age 25-27wks Naggert1 insulin   [ng/mL]   high-fat diet   18wks 43 strains   age 25-27wks Display strain means in the above table for: select a strain 129S1/SvImJ A/J AKR/J BALB/cByJ BALB/cJ BTBR T+ tf/J BUB/BnJ C3H/HeJ C57BL/10J C57BL/6J C57BLKS/J C57BR/cdJ C57L/J C58/J CAST/EiJ CBA/J CE/J CZECHII/EiJ DBA/1J DBA/2J FVB/NJ I/LnJ JF1/Ms KK/HlJ LP/J MA/MyJ MOLF/EiJ MSM/Ms NOD/ShiLtJ NON/ShiLtJ NZB/BlNJ NZW/LacJ PERA/EiJ PL/J PWK/PhJ RF/J RIIIS/J SEA/GnJ SJL/J SM/J SPRET/EiJ SWR/J WSB/EiJ   Compare two strains: select strain 1 129S1/SvImJ A/J AKR/J BALB/cByJ BALB/cJ BTBR T+ tf/J BUB/BnJ C3H/HeJ C57BL/10J C57BL/6J C57BLKS/J C57BR/cdJ C57L/J C58/J CAST/EiJ CBA/J CE/J CZECHII/EiJ DBA/1J DBA/2J FVB/NJ I/LnJ JF1/Ms KK/HlJ LP/J MA/MyJ MOLF/EiJ MSM/Ms NOD/ShiLtJ NON/ShiLtJ NZB/BlNJ NZW/LacJ PERA/EiJ PL/J PWK/PhJ RF/J RIIIS/J SEA/GnJ SJL/J SM/J SPRET/EiJ SWR/J WSB/EiJ vs. select strain 2 129S1/SvImJ A/J AKR/J BALB/cByJ BALB/cJ BTBR T+ tf/J BUB/BnJ C3H/HeJ C57BL/10J C57BL/6J C57BLKS/J C57BR/cdJ C57L/J C58/J CAST/EiJ CBA/J CE/J CZECHII/EiJ DBA/1J DBA/2J FVB/NJ I/LnJ JF1/Ms KK/HlJ LP/J MA/MyJ MOLF/EiJ MSM/Ms NOD/ShiLtJ NON/ShiLtJ NZB/BlNJ NZW/LacJ PERA/EiJ PL/J PWK/PhJ RF/J RIIIS/J SEA/GnJ SJL/J SM/J SPRET/EiJ SWR/J WSB/EiJ   Compare female vs. male for: select a strain 129S1/SvImJ A/J AKR/J BALB/cByJ BALB/cJ BTBR T+ tf/J BUB/BnJ C3H/HeJ C57BL/10J C57BL/6J C57BLKS/J C57BR/cdJ C57L/J C58/J CAST/EiJ CBA/J CE/J CZECHII/EiJ DBA/1J DBA/2J FVB/NJ I/LnJ JF1/Ms KK/HlJ LP/J MA/MyJ MOLF/EiJ MSM/Ms NOD/ShiLtJ NON/ShiLtJ NZB/BlNJ NZW/LacJ PERA/EiJ PL/J PWK/PhJ RF/J RIIIS/J SEA/GnJ SJL/J SM/J SPRET/EiJ SWR/J WSB/EiJ   Display overall measurement averages (all strains combined) in the above table

Notes

Svenson KL, Von Smith R, Magnani PA, Suetin HR, Paigen B, Naggert JK, Li R, Churchill GA, Peters LL. Multiple trait measurements in 43 inbred mouse strains capture the phenotypic diversity characteristic of human populations. J Appl Physiol. 2007 Jun;102(6):2369-78. Epub 2007 Feb 22.     PubMed    MGI There have been 6 updates or corrections to the dataset since it was first released in May, 2003 The insulin and leptin animal values are based on multiple test passes. Some strain means have N < 5 animals (click for table). Some measurements were derived by MPD staff, based on supplied data (click for list). See also the investigators' web site. This is one of several projects supplied by Heart, Lung, Blood and Sleep Disorders Center.

Downloads             Help

The Naggert1 project data set. Individual animal data in table format, with one row per animal and measurements organized as columns. Excel file Naggert1 individual animal data in list format. Most or all of the same information* as the file above, but organized as one row per animal / measurement. Excel file Naggert1 strain means, SD, SEM, N, Z-scores and other summary statistics. One row per strain / sex / measurement. Excel file These Excel files include data, descriptions, and units for all measurements listed above. Other download options are available via the Plots & Tools Wizard, above. Naggert1 protocol document HTML Naggert1 animal documentation HTML Supplemental data None