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Change Log

All updates and corrections to MPD data sets after initial release are logged here (see the MPD News page for info on initial releases). Bugs and bug fixes that impact MPD users will also be recorded in this changelog when warranted.

Note: current strain nomenclature is maintained in all downloadable data sets; nomenclature changes are generally not logged here but rather on the summary of strain nomenclature changes page.


Showing   Most recent at the top.


2009/10/15 Correction Project: WT-LXS  
  *48 and *78 data were switched. Also nomenclature changed to eg. ILSXISS48
 
2009/09/02 Correction Project: Lake1  
  Reticulocyte counts units changed from n/uL to n/L; values replaced w/ values computed from % Retic
 
2009/09/02 Correction Project: Svenson2  
  Units for reticulocytes corrected from n/µL to n/L; values not changed
 
2009/07/09 Update Project: Palmer2  
  PIs deleted 47 mostly older aged mice from data set.
 
2009/06/12 Correction Project: Lake3  
  accelerating rotarod, acceleration rate corrected in the descriptions
 
2009/06/12 Update Project: Tordoff3  
  calcium values had been supplied in mmol/L; we have converted them to mg/dL to conform to other similar data
 
2009/06/12 Correction Project: Xing1  
  extreme HR value for animal# SC-2489 (CBA/J male) was withdrawn per PI
 
2009/05/13 Update Project: Seburn2  
  New grip strength values added for 29 animals.
 
2009/03/27 Correction Project: QTL-Reifsnyder1  
  The excel file was updated by the source laboratory to correct minor error (Chr 'X' was denoted as '20')
 
2009/03/24 Update Project: Jax4  
  pictures for 3 additional strains added; summaries of appearance-related alleles added
 
2009/01/22 Correction Project: Graubert1  
  The age attribute was corrected from 9wks to 3-16mo for the cancer-related measurements. Project data set not changed.
 
2009/01/09 Clarification Project: Frankel1  
  Measurement descriptions, and project protocol have been reworked.
 
2009/01/09 Clarification Project: Mogil1  
  Measurement categories, descriptions, and presentation reworked. Protocol doc updated and expanded. Also, some strain means previously had an associated N that was given as a range eg. 6-10 . We now require a numeric N. We have retained the lower bound N value.
 
2008/12/19 Update Project: All-QTL  
  All of CGD's QTL archive Excel files ... cM locations were updated by the CGD lab.
 
2008/11/20 Update Project: Peters4  
  Complete refresh; additional data.
 
2008/11/19 Correction Project: Golani1  
  Units were incorrect in several measurement descriptions -- fixed. Also measurements now organized into blocks.
 
2008/10/31 Clarification  
  Phenotype strain survey categories ... A number of adjustments have been made to phenotype category terms.
 
2008/10/31 Correction Project: Jaxwest1  
  QTc ECG values corrected for all strains. MPD staff rederived QTc using standard formula.
 
2008/10/31 Update Project: Jaxwest1  
  grip strength now expressed in grams (had been in kg)
 
2008/10/31 Update Project: Lake3  
  grip strength now expressed in grams (had been in kg)
 
2008/09/16 Correction  
  SNP tool bug fix. In the Find Genomic Regions exploratory tool, for queries where neither group included the reference strain C57BL/6J, plotted bar heights sometimes did not adequately indicate the underlying SNP differences between the two strain groups. This bug has been fixed... users of the Find Genomic Regions exploratory tool should always verify results by clicking through to the SNP strain comparison plot.
 
2008/09/04 Correction  
  SNP tool bug fix. When the polymorphism matrix tool was run using CGD1 imputed data, computed % polymorphic was incorrect (imputed alleles are represented using lower case but the matrix computation erroneously considered eg. "g" different from "G"). The problem is now fixed, however any polymorphism matrices involving CGD1 imputed allele data that were produced from 29May2008 until 04Sep2008 should be considered incorrect.
 
2008/08/25 Correction  
  Ratios and differences plot tool bug fix. Tool was in some cases displaying a juxtaposition of female and male data points.. usually obvious when occurring.. Fixed.
 
2008/08/13 Correction Project: Korstanje1  
  Ratios were incorrect as originally posted (based on incorrect units); fixed.
 
2008/08/13 Correction Project: Korstanje1  
  Microalbumin and creatinine measurement units were incorrect as originally posted; fixed.
 
2008/07/24 Correction Project: Donahue1  
  IGF-1 units were incorrectly stated as ng/dL... corrected to ng/mL per investigator. Also clarified that these are adjusted values (see protocol section IIIg)
 
2008/06/17 Correction Project: Richfield1  
  short term and long term habituation data had been reversed
 
2008/06/17 Clarification Project: Richfield1  
  beam breaks measurement descriptions clarified
 
2008/04/30 Update Project: Jax4  
  new pictures added for 12 strains; some appearance descriptions adjusted
 
2008/04/18 Update Project: Schwartz2  
  Project was reworked to emphasize lavage cell count data and de-emphasize Buxco data, on the advice of experts in the community. All of the measurements that were formerly in this project are no longer available (serial numbers retired).
 
2008/04/18 Correction Project: Tomasini1  
  Investigator provided corrected values for all AKR animals
 
2008/04/18 Update Project: Willott1  
  se genotype appended to SEA/GnJ animal ids where known
 
2008/03/11 Correction Project: Crabbe1  
  Data corruption issue. Data from this project as presented on the MPD web site between 1 Oct 2007 and 14 Mar 2008 should be considered invalid, due to a file manipulation error that occurred on 1 Oct 2007. This problem was discovered 11 Mar 2008. The data have been restored and are now considered to be correct.
 
2008/03/10 Update  
  Diet terminology change ... In many of the HLB projects we had used the term "atherogenic diet" to refer to the particular 15% fat diet that was administered. We now use the term "high-fat diet" instead.
 
2008/02/08 Correction Project: Jaxpheno1  
  Original data set did not have unique animal ids within strain/sex groups. Added animal id suffixes to make them unique.
 
2008/02/08 Correction Project: Jaxpheno2  
  Original data set did not have unique animal ids within strain/sex groups. Added animal id suffixes to make them unique.
 
2008/02/08 Correction Project: Jaxpheno3  
  Original data set did not have unique animal ids within strain/sex groups. Added animal id suffixes to make them unique.
 
2008/02/08 Correction Project: Jaxpheno4  
  Original data set did not have unique animal ids within strain/sex groups. Added animal id suffixes to make them unique.
 
2008/02/08 Update Project: Jaxpheno5  
  Animal IDs were not supplied in the original data set. We added unique serial numbers to each data point.
 
2008/02/08 Correction Project: Jaxpheno6  
  Original data set did not have unique animal ids within strain/sex groups. Added animal id suffixes to make them unique.
 
2008/02/01 Correction Project: Jaxpheno4  
  Data corruption issue, Jaxpheno4, Nov '07 to Feb 1 '08. In approx. mid-November some unpublished consomic data went into the MPD database that mistakenly used Jaxpheno4 measurement ids. Certain MPD data displays and retrievals involving Jaxpheno4 measurements data during this time should be considered incorrect and invalid. Invalid results will likely include B6.PWD consomic strain names.
 
2008/01/08 Correction  
  SNP tool bug fix. A problem was discovered and fixed in the SNP-based Find Genomic Regions tool (beta) on 8 Jan 2008 2pm EST. Results derived from this tool from 4 Jan 2008 to 8 Jan 2008 are likely to be invalid. Also, this tool was operating in Build 36 space until 4 Jan 2008, while the rest of the MPD SNPs system was operating in Build 37 space since 21 Dec 2007.
 
2007/12/21 Update  
  SNPs updated to NCBI mouse genome build 37 / dbSNP 128 / Ensembl v48.
 
2007/10/02 Correction Project: Jaxwest1  
  Respiratory measurements withdrawn.
 
2007/05/30 Correction Project: Broad1  
  in the Broad1 data, corrected some basepair locations on Chr 3 and Chr 5 that were incorrect (off by 1 to 3 basepairs) due to processing errors when mapping to Build 36.
 
2006/12/19 Update Project: Jax4  
  photos for additional strains added.
 
2006/11/07 Correction Project: Broad1  
  incorrect strain BALB/cJ corrected to: BALB/cByJ (error introduced during mapping to Build 36).
 
2006/10/24 Correction Project: Seburn1  
  the units attribute was corrected for cal and cal adj
 
2006/10/06 Update Project: Mcminimy1  
  Build 36 basepair coordinates added for Mit markers where available from MGI
 
2006/08/11 Update  
  SNPs updated to NCBI mouse genome build 36.
 
2006/08/11 Update Project: Perlegen2  
  Additional data.
 
2006/07/12 Update Project: Crabbe1  
  variable names changed to remove embedded periods, data not changed
 
2006/04/03 Correction Project: Jax2  
  Haplotypes have no gender component; data replicated for females as well as males.
 
2006/03/21 Update Project: Paigen2  
  4 MOLF male data points added (CHOL) and fold change also computed.
 
2006/02/06 Correction Project: Peters1  
  In the protocol doc, hematology sample collection description was changed.
 
2006/02/06 Correction Project: Peters2  
  In the protocol doc, hematology sample collection description was changed.
 
2006/02/06 Correction Project: Peters3  
  In the protocol doc, hematology sample collection description was changed.
 
2005/09/15 Update Project: Naggert1  
  Complete update provided by source lab. HOMA dropped.
 
2005/09/15 Update Project: Paigen2  
  Cholesterol and triglyceride values updated by source lab. Values for 10 wk old animals were removed from this project and moved into a new project, Paigen4.
 
2005/06/02 Update Project: Naggert1  
  Data set was completely updated by source lab, with some additional strain data points added. Some measurements that were formerly available have been deleted.
 
2005/04/20 Correction Project: Peters1  
  Per investigator, original C57BL/6J Retic values were withdrawn (code=WD) and replaced by Retic values from 20 female and 20 male B6 seasonal controls that were tested during the same time period.
 
2004/10/29 Update Project: Schwartz2  
  MPD project reorganized and re-released; supersedes Schwartz1.. Schwartz1 deleted.
 
2004/08/20 Correction Project: Peters1  
  Fixed error in meas description for Retic (6217)
 
2004/08/02 Correction Project: Johnson1  
  Animal IDs created by MPD for conformity.
 
2004/07/20 Update Project: Golani1  
  New measurements added.
 
2004/06/12 Correction Project: Paigen1  
  data not changed; the phrase 'after 8 wks on atherogenic diet' was added to many meas descriptions
 
2004/04/27 Update Project: Deschepper1  
  Adrenal images added; categories revised.
 
2004/04/16 Update Project: Naggert1  
  new measurement (HOMA 18) added to dataset
 
2004/03/31 Update Project: Dietrich1  
  Changed to use R and S rather than 90 and 10
 
2004/03/23 Update Project: Paigen2  
  Ages were adjusted for some measurements. Also, previously there had been separate 8 week and 10 week baseline measurements... these have been combined, resulting in a single baseline measurement for each of HDLC, nonHDLC, total cholesterol, and triglycerides.
 
2004/03/19 Update Project: Naggert1  
  New measurement: BMI 8 replaces body length
 
2004/02/20 Update Project: Paigen1  
  aortic lesion measurement added
 
2004/02/20 Update Project: Paigen2  
  aortic lesion measurement added
 
2004/02/20 Update Project: Paigen3  
  aortic lesion measurement added
 
2004/02/17 Update Project: Naggert1  
  new insulin, leptin, bone mineral and body comp. measurements added; new body weight data points
 
2004/02/16 Correction Project: Paigen1  
  NZW/LacJ #23 changed from male to female
 
2004/01/20 Update Project: Tordoff3  
  new measurements added- bone mineral and body composition
 
2003/12/22 Update Project: Naggert1  
  hormone and body weight measurements added
 
2003/08/14 Update Project: Mogil1  
  New measurements added. Measurement categories reorganized.
 
2003/04/18 Update Project: Peters1  
  Update of advia data for 13 strains.
 
2003/03/26 Update Project: Peters1  
  Complete update from laboratory.
 
2003/03/05 Update Project: Paigen1  
  body weight change was expressed as a percent, now expressed as a fold (1.00 = no change)
 
2003/03/05 Update Project: Paigen3  
  body weight change had been expressed as a percent; now expressed as a fold (1.00 = no change)
 
2003/03/05 Update Project: Tordoff3  
  body weight change had been expressed as a percent; now expressed as a fold (1.00 = no change)
 








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