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All phenotype strain survey data > Intervention: diazepam        
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behavior — activity and motor function &ndash animal monitoring system  
Crabbe2
horizontal distance traveled (immediately to 15min post-injection) [cm]     baseline and  diazepam
      • baseline  • 2 mg/kg  • 4 mg/kg  • 8 mg/kg  • 16 mg/kg    dose effect comparison  
15 strains   age 6-7wks
Crabbe2
vertical (rearing) activity (immediately to 15min post-injection) [n]     baseline and  diazepam
      • baseline  • 2 mg/kg  • 4 mg/kg  • 8 mg/kg  • 16 mg/kg    dose effect comparison  
15 strains   age 6-7wks
 
behavior — activity and motor function &ndash rotarod  
Crabbe2
latency to fall from 5rpm rotarod, 0 min post-injection [s]   diazepam   20 mg/kg
      • trial block1  • trial block2    trial block comparison  
15 strains   age 6-7wks
 
brain — physiology and function — drug concentration  
Crabbe2
brain diazepam and metabolite concentration (30min post-injection) [ng/g]   diazepam
      • 8 mg/kg  • 16 mg/kg    dose effect comparison  
15 strains   age 6-7wks
Crabbe2
brain diazepam and metabolite concentration (<5min post-injection) after rotarod [ng/g]   diazepam   20 mg/kg
      • trial block1  • trial block2    trial block comparison  
15 strains   age 6-7wks
 
metabolism — body temperature  
Crabbe2
body temperature (30min post-injection) [°C]     baseline and  diazepam
      • baseline  • 2 mg/kg  • 4 mg/kg  • 8 mg/kg  • 16 mg/kg    dose effect comparison  
15 strains   age 6-7wks


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