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All phenotype strain survey data > Intervention: EtOH        
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behavior — activity and motor function &ndash balance beam  
Crabbe1
missteps crossing balance beam [n]     control and  EtOH
        12.7mm beam:   • control      i.p. doses:   • 1.0g/kg     • 1.2g/kg     • 1.4g/kg    EtOH dose effect comparison  
        15.8mm beam:   • control      i.p. doses:   • 1.0g/kg     • 1.2g/kg     • 1.4g/kg    EtOH dose effect comparison  
        19.0mm beam:   • control      i.p. doses:   • 1.0g/kg     • 1.2g/kg     • 1.4g/kg    EtOH dose effect comparison  
        compare by beam width:   control 0     1.0g/kg     1.2g/kg     1.4g/kg 
8 strains   age 8-16wks
 
behavior — activity and motor function &ndash grid test  
Crabbe1
grid habituation, distance traveled [cm]     control and  EtOH
      • control    i.p. doses: • 1.5g/kg   • 2.0g/kg   • 2.5g/kg    EtOH dose effect comparison  
8 strains   age 8-16wks
Crabbe1
grid habituation, missteps per cm [n/cm]     control and  EtOH
      • control    i.p. doses: • 1.5g/kg   • 2.0g/kg   • 2.5g/kg    EtOH dose effect comparison  
8 strains   age 8-16wks
 
behavior — activity and motor function &ndash open field test  
Metten1
line crossings, 2.75g/kg injection [n]     control and  EtOH 2.75g/kg i.p.
      • pre-injection 
      • 10 min after injection 
      • 30 min after 
        time after EtOH comparison  
9 strains   age 8-11wks
Metten1
line crossings, 3.0g/kg injection [n]     control and  EtOH 3.0g/kg i.p.
      • pre-injection 
      • 10 min after injection 
      • 30 min after 
        time after EtOH comparison  
9 strains   age 8-11wks
Metten1
line crossings, compare dose groups     control and  EtOH
      pre-injection 
      10 min after injection 
      30 min after 
     
8 strains   age 8-16wks
 
behavior — activity and motor function &ndash parallel rod floor apparatus  
Crabbe5
distance traveled, 1.6mm rod, 6mm space [cm]     control and  EtOH
      • day1(control 0) 
      • day2(control 0) 
      • day3(2g/kg i.p.) 
        EtOH dose effect comparison  
8 strains   age 8-10wks
Crabbe5
motor incoordination (errors/distance traveled)
1.6mm rod, 6mm space [n/cm]  
  control and  EtOH
      • day1(control 0) 
      • day2(control 0) 
      • day3(2g/kg i.p.) 
        EtOH dose effect comparison  
8 strains   age 7-14wks
 
behavior — activity and motor function — handling-induced convulsion  
Metten2
peak handling-induced convulsion score [score]     control and  EtOH aerosolized
      • control 
      • aerosolized EtOH 
      • aerosolized EtOH normalized to controls 
     
15 strains   age 8-15wks
Metten2
latency to first score used to calculate peak EtOH   [h]   EtOH   aerosolized
15 strains   age 8-15wks
Metten2
withdrawal severity during 0-25 h (area under curve of HIC scores) [unit2]   EtOH   aerosolized
      • aerolized EtOH 
      • aerolized EtOH normalized to controls 
     
15 strains   age 8-15wks
 
behavior — activity and motor function — observer-rated ataxia  
Metten1
hindlimb splay, 2.75g/kg injection [score]   EtOH   2.75g/kg i.p.
      • 10 min after injection 
      • 30 min after 
        time after EtOH comparison  
9 strains   age 8-11wks
Metten1
hindlimb splay, 3.0g/kg injection [score]   EtOH   3.0g/kg i.p.
      • 10 min after injection 
      • 30 min after 
        time after EtOH comparison  
9 strains   age 8-11wks
Metten1
erratic gait, 2.75g/kg injection [score]   EtOH   2.75g/kg i.p.
      • 10 min after injection 
      • 30 min after 
        time after EtOH comparison  
9 strains   age 8-11wks
Metten1
erratic gait, 3.0g/kg injection [score]   EtOH   3.0g/kg i.p.
      • 10 min after injection 
      • 30 min after 
        time after EtOH comparison  
9 strains   age 8-11wks
Metten1
compare dose groups   EtOH  
      hindlimb splay:
            10 min after 
            30 min after 
      erratic gait:
            10 min after 
            30 min after 
           
8 strains   age 8-16wks


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