All phenotype strain survey data > Intervention: APAP

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blood chemistry — enzymes
Threadgill1	ALT [IU/L]     control and  APAP       100 mg/kg: • control  • 4h  • 12h  • 24h    time comparison	37 strains   age 8-17wks
Threadgill1	AST [IU/L]     control and  APAP       • control        post-APAP:             • 100 mg/kg              • 200 mg/kg              • 300 mg/kg                dose effect comparison	37 strains   age 8-17wks
blood chemistry — urea nitrogen
Threadgill1	BUN [mg/dL]     control and  APAP       • control        post-APAP:             • 100 mg/kg              • 200 mg/kg              • 300 mg/kg                dose effect comparison	36 strains   age 8-17wks
liver and gallbladder — function — enzymes
Threadgill1	catalase [µg/mL]     control and  APAP 300 mg/kg       • control        • post-APAP 300 mg/kg          Rx effect comparison	36 strains   age 8-12wks
Threadgill1	cytochrome P450 1A2 isoform [pmol/mg]     control and  APAP 300 mg/kg       • control        • post-APAP 300 mg/kg          Rx effect comparison	36 strains   age 8-12wks
Threadgill1	cytochrome P450 2E1 isoform [pmol/mg]     control and  APAP 300 mg/kg       • control        • post-APAP 300 mg/kg          Rx effect comparison	36 strains   age 8-12wks
Threadgill1	glutathione transferase Pi [µg/mL]     control and  APAP 300 mg/kg       • control  • post-APAP 300 mg/kg	36 strains   age 8-12wks
liver and gallbladder — function — proteins
Threadgill1	GSH [µmol/g]     control and  APAP       • control        • post-APAP 300mg/kg          Rx effect comparison	35 strains   age 8-17wks
Threadgill1	GSSG [µmol/g]     control and  APAP       • control        • post-APAP 300mg/kg          Rx effect comparison	35 strains   age 8-17wks
Threadgill1	total glutathione [µmol/g]     control and  APAP       • control        • post-APAP 300 mg/kg          Rx effect comparison	37 strains   age 8-17wks
Threadgill1	ratio of reduced to oxidized glutathione [ratio]     control and  APAP       • control        • post-APAP 300mg/kg          Rx effect comparison	35 strains   age 8-17wks
liver and gallbladder — liver morphology
Threadgill1	liver weight [g]     control and  APAP       • control        24h post-APAP:             • 100mg/kg              • 200mg/kg              • 300mg/kg                dose effect comparison	37 strains   age 8-17wks
liver and gallbladder — liver pathology
Threadgill1	necrosis [%]     control and  APAP       • control        post-APAP:             • 100mg/kg              • 200 mg/kg              • 300 mg/kg                dose effect comparison	37 strains   age 8-17wks

Display strain means in the above table for: select a strain 129S1/SvImJ A/J AKR/J B6C3F1/J BALB/cByJ BTBR T+ tf/J BUB/BnJ C3H/HeJ C57BL/10J C57BL/6J C57BLKS/J C57BR/cdJ C57L/J CAST/EiJ CBA/J CZECHII/EiJ DBA/2J FVB/NJ JF1/Ms KK/HlJ LP/J MA/MyJ MSM/Ms NOD/ShiLtJ NON/ShiLtJ NZO/HlLtJ NZW/LacJ P/J PERA/EiJ PL/J PWD/PhJ RIIIS/J SEA/GnJ SJL/J SM/J SWR/J WSB/EiJ

Compare two strains: select strain 1 129S1/SvImJ A/J AKR/J B6C3F1/J BALB/cByJ BTBR T+ tf/J BUB/BnJ C3H/HeJ C57BL/10J C57BL/6J C57BLKS/J C57BR/cdJ C57L/J CAST/EiJ CBA/J CZECHII/EiJ DBA/2J FVB/NJ JF1/Ms KK/HlJ LP/J MA/MyJ MSM/Ms NOD/ShiLtJ NON/ShiLtJ NZO/HlLtJ NZW/LacJ P/J PERA/EiJ PL/J PWD/PhJ RIIIS/J SEA/GnJ SJL/J SM/J SWR/J WSB/EiJ vs. select strain 2 129S1/SvImJ A/J AKR/J B6C3F1/J BALB/cByJ BTBR T+ tf/J BUB/BnJ C3H/HeJ C57BL/10J C57BL/6J C57BLKS/J C57BR/cdJ C57L/J CAST/EiJ CBA/J CZECHII/EiJ DBA/2J FVB/NJ JF1/Ms KK/HlJ LP/J MA/MyJ MSM/Ms NOD/ShiLtJ NON/ShiLtJ NZO/HlLtJ NZW/LacJ P/J PERA/EiJ PL/J PWD/PhJ RIIIS/J SEA/GnJ SJL/J SM/J SWR/J WSB/EiJ

Compare female vs. male for: select a strain 129S1/SvImJ A/J AKR/J B6C3F1/J BALB/cByJ BTBR T+ tf/J BUB/BnJ C3H/HeJ C57BL/10J C57BL/6J C57BLKS/J C57BR/cdJ C57L/J CAST/EiJ CBA/J CZECHII/EiJ DBA/2J FVB/NJ JF1/Ms KK/HlJ LP/J MA/MyJ MSM/Ms NOD/ShiLtJ NON/ShiLtJ NZO/HlLtJ NZW/LacJ P/J PERA/EiJ PL/J PWD/PhJ RIIIS/J SEA/GnJ SJL/J SM/J SWR/J WSB/EiJ

Display overall measurement averages (all strains combined) in the above table

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