Ontology terms mapped to Vanderlinden1 measures:

  MP:0001259   abnormal body weight MGI
  MP:0001425   abnormal alcohol consumption MGI
  VT:0001259   body mass
  VT:0001422   drinking behavior trait

Investigators	Lauren A Vanderlinden       University of Colorado,  Aurora, CO Laura Saba       University of Colorado Denver School of Medicine,  Aurora, CO Beth Bennett       University of Colorado Denver School of Medicine,  Aurora, CO Paula A Hoffman       University of Colorado Denver School of Medicine,  Aurora, CO Boris Tabakoff       University of Colorado Denver School of Medicine,  Aurora, CO
Contact	Lauren A Vanderlinden     lauren.vanderlinden@ucdenver.edu
Acknowledgements	Funding provided by NIH AA013162, AA16649; Banbury Fund
Project type	Phenotype strain survey data set
MPD identifiers	Vanderlinden1     MPD:543
Data changelog	No updates/corrections.       Initial release date: 04/2016.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

ILSXISS recombinant inbred mice were used to investigate genetic influences of alcohol consumption in the "drinking in the dark" model. Mice were given access to 20% ethanol during the early phase of their circadian dark cycle for four consecutive days. Alcohol-preferring strains of mice consume an amount of alcohol during this time that produces blood ethanol levels that are comparable to the levels that define binge drinking in humans.

Procedures conducted:

• body weight
• intake monitoring		Ethanol consumed during 2h availability during dark phase. 4 days/trials with variations.