Tordoff1: Diet preference: Survey of salt preference in drinking water for males of 28 inbred strains of mice (2001)

Bachmanov AA, Beauchamp GK, Tordoff MG. Voluntary consumption of NaCl, KCl, CaCl2 and NH4Cl solutions by 28 mouse strains. Behav Genet. 2002 Nov;32(6):445-457.   PubMed 12467342  


       
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Participants Michael G Tordoff       Monell Chemical Senses Center Philadelphia, PA
Alexander A Bachmanov       Monell Chemical Senses Center Philadelphia, PA
ContactMichael G Tordoff     tordoff@monell.org
AffiliationMonell Chemical Senses Center
AcknowledgementsFunding provided by DK46791, AA12715, AA11028, DC03854
Project type Phenotype strain survey data set
MPD identifiersTordoff1     MPD:61
Data changelog 1 update/correction.       Initial release date: 06/2001.
Formatted citation
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Taste preferences between two fluid sources were measured:
  • NaCl solution vs. water, using concentrations of 75, 150, 300, and 450 mM
  • KCl solution vs. water, using concentrations of 10, 30, 100, 200, and 300 mM
  • CaCl2 solution vs. water, using concentrations of 3, 10, 30, and 100 mM
  • NH4Cl solution vs. water, using concentrations of 10, 30, 100 and 300 mM
For each solution and concentration, intake was measured over a 48h period, and preference ratios (solution vs. water) computed. These preference ratios (%) are presented as MPD measurements.

Summary of procedures that were conducted
• body weight Body weight during testing.
• bottle choice test Various salt solutions (several concentrations) vs. water.
Mice: inbred   28 strains   ♂   age 9wks   1 cohort

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Tordoff1 6103 bottle choice test (none) preference for NaCl (sodium chloride) solutions   [%]     75mM    150    300    450 inbred 28 m 4-12wks N=12
    Tordoff1 6109 bottle choice test (none) preference for KCl (potassium chloride) solutions   [%]     10mM    30    100    200    300 inbred 28 m 4-12wks N=12
    Tordoff1 6116 bottle choice test (none) preference for CaCl2 (calcium chloride) solutions   [%]     3mM    10    30    100 inbred 28 m 4-12wks N=12
    Tordoff1 6122 bottle choice test (none) preference for NH4Cl (ammonium chloride) solutions   [%]     10mM    30    100    300 inbred 28 m 4-12wks N=12
    All boxes