Marchuk1: Surgically-induced cerebral infarct volume for assessing stroke susceptibility in 16 inbred strains of mice (2009)

Keum S, Marchuk DA. A locus mapping to mouse chromosome 7 determines infarct volume in a mouse model of ischemic stroke. Circ Cardiovasc Genet. 2009 Dec;2(6):591-8. Epub 2009 Oct 19.   PubMed 20031639     FullText


       
Marchuk1 downloads
• Download Marchuk1 project data set     one row per animal, one column per trait
• Download Marchuk1 strain means, SD, N, etc.     one row per strain/sex/measure
Participants Douglas A Marchuk       Duke University Medical Center Durham, NC
With: Keum S
ContactDouglas A Marchuk     douglas.marchuk@duke.edu     Lab web site
AcknowledgementsFunded by NIH HL097281 and American Heart Association 0815132E.
Project type Phenotype strain survey data set
MPD identifiersMarchuk1     MPD:450
Data changelog No updates/corrections.       Initial release date: 01/2013.
Formatted citation
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Summary of procedures that were conducted
• histopathology Cerebral infarct volume, stroke susceptibility. Surgical occlusion of distal medial cerebral artery (MCA) to induce ischemia.
Mice: inbred   16 strains   ♀♂   age 11-13wks   1 cohort

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Marchuk1 45001 histopathology (none) infarct volume following surgically-induced focal cerebral ischemia   [mm3]  infarct_vol inbred 16 both 11-13wks N=4
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