Jaxwest15: Drug study: Efficacy of Docetaxel and Paclitaxel in a patient-derived mammary carcinoma xenograft model in female NOD scid gamma (NSG) immunodeficient mice (2013)

Yang Y

     
Purpose of study:
To determine the therapeutic efficacy of two standard of care drugs (Docetaxel and Paclitaxel) in a patient-derived mammary carcinoma xenograft (PDX) model in female NOD scid gamma (NSG) immunodeficient mice.

Jaxwest15 downloads
See below for available data set downloads.
Participants Yan Yang       The Jackson Laboratory Bar Harbor, ME
ContactYan Yang     yan.yang@jax.org     Lab web site
AffiliationJackson Laboratory In Vivo Services
Project type One-strain study
MPD identifiersJaxwest15     MPD:499
Data changelog No updates/corrections.       Initial release date: 01/2014.
Formatted citation
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• Download data set: Jaxwest15.xlsx

Protocol and experimental design

• Study involves NSG females
  Full strain name: NOD.Cg-Prkdcscid_Il2rgtm1Wjl/SzJ




• Additional information

        • Docetaxel (Wikipedia)

        • Paclitaxel (Wikipedia)

        • PDX triple negative mammary carcinoma: TM00089   (BR0602F)

        • More info on PDX models for breast cancer research



By posting these data, JAX In Vivo Pharmacology Services contributes to community research resources and fulfills an agreement with clients to make normative data public.