Iraqi1: Susceptibility to periodontitis in 4 inbred strains and 19 emerging lines (pre-CC) of the Collaborative Cross (2013)

Shusterman A, Salyma Y, Nashef A, Soller M, Wilensky A, Mott R, Weiss EI, Houri-Haddad Y, Iraqi FA. Genotype is an important determinant factor of host susceptibility to periodontitis in the Collaborative Cross and inbred mouse populations. BMC Genet. 2013 Aug 9;14:68. doi: 10.1186/1471-2156-14-68.   PubMed 23937452     FullText


       
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Participants Fuad A Iraqi       Tel Aviv University Tel Aviv ISRAEL
With: Shusterman A, Salyma Y, Nashef A, Soller M, Wilensky A, Mott R, Weiss EI, Houri-Haddad Y
ContactFuad A Iraqi     fuadi@post.tau.ac.il     Lab web site
Project type Phenotype strain survey data set
MPD identifiersIraqi1     MPD:495
Data changelog 1 update/correction.       Initial release date: 12/2013.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
An assessment of selected emerging CC lines. Generations range from G2:F10 to G2:F18. Data for 2 founder strains are also present, as well as for 2 other inbred strains.

Summary of procedures that were conducted
• computed tomography Susceptibility to periodontitis. Mice infected with P. gingivalis and F. nucleatum vs. control.
Mice: CC pre   23 strains   ♀♂   age 8wks   2 cohorts

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Iraqi1 49501 computed tomography P.gingivalis and F.nucleatum  control bone volume of the maxillary jaw (x 10-3), uninfected   [mm3]  control_bone_vol CC pre 21 both 8wks N=4
    Iraqi1 49502 computed tomography P.gingivalis and F.nucleatum residual bone volume of the maxillary jaw (x 10-3), post-infection (peridontitis)   [mm3]  residual_bone_vol CC pre 23 both 8wks N=3
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