Hackstein1: Respiratory dendritic cell subsets and lymphocyte populations in 5 inbred strains of mice (2012)

Hackstein H, Wachtendorf A, Kranz S, Lohmeyer J, Bein G, Baal N. Heterogeneity of respiratory dendritic cell subsets and lymphocyte populations in inbred mouse strains. Respir Res. 2012 Oct 15;13:94. doi: 10.1186/1465-9921-13-94.   PubMed 23066782     FullText


       
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Participants Holger Hackstein       Justus-Liebig University Giessen GERMANY
With: Wachtendorf A, Kranz S, Lohmeyer J, Bein G, Baal N
ContactHolger Hackstein     Holger.Hackstein@immunologie.med.uni-giessen.de
AcknowledgementsFunding provided by German Science Foundation; University Giessen and Marburg Lung Center
Project type Phenotype strain survey data set
MPD identifiersHackstein1     MPD:491
Data changelog No updates/corrections.       Initial release date: 10/2013.
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Summary of procedures that were conducted
• immune cell quantification Respiratory dendritic cell subsets and lymphocyte populations.
Mice: inbred   5 strains   ♂   age 7-11wks   2 cohorts

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Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Hackstein1 49101 immune cell quantification (none) total leukocyte count (x 103)   [n]  BAL inbred 5 m 7-11wks N=5
    Hackstein1 49102 immune cell quantification (none) macrophages (percentage of BAL leukocytes)   [%]  BAL_MAC inbred 5 m 7-11wks N=5
    Hackstein1 49103 immune cell quantification (none) dendritic cells (percentage of CD45+ cells)   [%]  DC inbred 5 m 7-11wks N=9
    Hackstein1 49104 immune cell quantification (none) plasmacytoid dendritic cells (percentage of CD45+ cells)   [%]  DC_plasmacytoid inbred 5 m 7-11wks N=9
    Hackstein1 49105 immune cell quantification (none) monocytic dendritic cells (percentage of CD45+ cells)   [%]  DC_monocytic inbred 5 m 7-11wks N=9
    Hackstein1 49106 immune cell quantification (none) CD103+ dendritic cells (percentage of CD45+ cells)   [%]  DC_103 inbred 5 m 7-11wks N=9
    Hackstein1 49107 immune cell quantification (none) CD11bhi MHChi dendritic cells (percentage of CD45+ cells)   [%]  DC_11b inbred 5 m 7-11wks N=9
    Hackstein1 49108 immune cell quantification (none) Siglec F+ F4/80+ macrophages (percentage of CD45+ cells)   [%]  MAC inbred 5 m 7-11wks N=9
    Hackstein1 49109 immune cell quantification (none) neutrophils (percentage of CD45+ cells)   [%]  NEUT inbred 5 m 7-11wks N=9
    Hackstein1 49110 immune cell quantification (none) eosinophils (percentage of CD45+ cells)   [%]  EOS inbred 5 m 7-11wks N=9
    Hackstein1 49111 immune cell quantification (none) Linneg CD90+ innate cells (percentage of CD45+ cells)   [%]  Lin_neg_90_plus inbred 5 m 7-11wks N=6
    Hackstein1 49112 immune cell quantification (none) Linneg CD90- innate cells (percentage of CD45+ cells)   [%]  Lin_neg_90_neg inbred 5 m 7-11wks N=6
    Hackstein1 49113 immune cell quantification (none) CD19+ B cells (percentage of CD45+ cells)   [%]  B_cells inbred 5 m 7-11wks N=8
    Hackstein1 49114 immune cell quantification (none) CD3+ T cells (percentage of CD45+ cells)   [%]  T_CD3 inbred 5 m 7-11wks N=9
    Hackstein1 49115 immune cell quantification (none) CD3+ CD8+ T cells (percentage of CD45+ cells)   [%]  T_CD8 inbred 5 m 7-11wks N=9
    Hackstein1 49116 immune cell quantification (none) CD3+ CD4+ T cells (percentage of CD45+ cells)   [%]  T_CD4 inbred 5 m 7-11wks N=9
    Hackstein1 49117 immune cell quantification (none) CD3+ CD4+ CD25+ T cells (percentage of CD45+ cells)   [%]  T_CD4_25 inbred 5 m 7-11wks N=8
    Hackstein1 49118 immune cell quantification (none) CD3+ CD4+ CD25hi Treg cells (percentage of CD45+ cells)   [%]  T_CD4_25hi inbred 5 m 7-11wks N=5
    Hackstein1 49119 immune cell quantification (none) CD3+ CD4+ CD25hi Foxp3+ Treg cells (percentage of CD45+ cells)   [%]  T_CD4_foxp3 inbred 5 m 7-11wks N=5
    Hackstein1 49120 immune cell quantification (none) CD3+ CD4+ CD25hi Foxp3+ CD39+ Treg cells (percentage of CD45+ cells)   [%]  T_CD4_39 inbred 5 m 7-11wks N=5
    Hackstein1 49121 immune cell quantification (none) CD3+ gamma-delta T cells (percentage of CD45+ cells)   [%]  T_gd inbred 5 m 7-11wks N=9
    Hackstein1 49122 immune cell quantification (none) CD49+ natural killer (NK) cells (percentage of CD45+ cells)   [%]  NK inbred 5 m 7-11wks N=9
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