HMDPpheno1: Bone mineral density in males of 96 strains of mice in the Hybrid Mouse Diversity Panel (HMDP) (2011)

Farber CR, Bennett BJ, Orozco L, Zou W, Lira A, Kostem E, Kang HM, Furlotte N, Berberyan A, Ghazalpour A, Suwanwela J, Drake TA, Eskin E, Wang QT, Teitelbaum SL, Lusis AJ. Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis. PLoS Genet. 2011 Apr;7(4):e1002038. doi: 10.1371/journal.pgen.1002038. Epub 2011 Apr 7.   PubMed 21490954     FullText


       
HMDPpheno1 downloads
• Download HMDPpheno1 project data set     one row per animal, one column per trait
• Download HMDPpheno1 strain means, SD, N, etc.     one row per strain/sex/measure
Participants Charles R Farber       University of Virginia Charlottesville, VA
Brian J Bennett       University of North Carolina Chapel Hill, NC
Luz Orozco       University of California, Los Angeles Los Angeles, CA
Eleazar Eskin       University of California, Los Angeles Los Angeles, CA
Aldons J Lusis       University of California, Los Angeles Los Angeles, CA
With: Zou W, Lira A, Kostem E, Kang HM, Furlotte N, Berberyan A, Ghazalpour A, Suwanwela J, Drake TA, Wang QT, Teitelbaum SL
ContactCharles R Farber     crf2s@virginia.edu     Lab web site
AffiliationHybrid Mouse Diversity Panel Group (HMDP)
AcknowledgementsFunding provided by the NIH HL28481, DK074317
Project type Phenotype strain survey data set
MPD identifiersHMDPpheno1     MPD:446
Data changelog 1 update/correction.       Initial release date: 12/2012.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
The Hybrid Mouse Diversity Panel (HMDP) includes inbred strains as well as AXB, BXA, BXD, and BXH strains. Data can be analyzed for all the HMDP strains together, or by strain panel subset.

Summary of procedures that were conducted
• DXA Bone mineral density (whole body, femur, spine).
Mice: HMDP   96 strains including progenitors   ♂   age 16wks   1 cohort

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    HMDPpheno1 44601 DXA (none) whole body bone mineral density (BMD; skull, lumbar spine, left femur excluded)   [g/cm2]  BMD_body HMDP w/par 96 m 16wks N=9
    HMDPpheno1 44602 DXA (none) bone mineral density (BMD) of left femur   [g/cm2]  BMD_femur HMDP w/par 96 m 16wks N=9
    HMDPpheno1 44603 DXA (none) bone mineral density (BMD) of lumbar spine   [g/cm2]  BMD_spine HMDP w/par 96 m 16wks N=9
    All boxes