Gros2: Susceptibility to infection with Plasmodium chabaudi chabaudi AS (malaria) in 25 inbred strains of mice (2012)

Laroque A, Min-Oo G, Tam M, Radovanovic I, Stevenson MM, Gros P. Genetic control of susceptibility to infection with Plasmodium chabaudi chabaudi AS in inbred mouse strains. Genes Immun. 2012 Feb;13(2):155-63. doi: 10.1038/gene.2011.67. Epub 2011 Oct 6.   PubMed 21975430  


       
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Participants Philippe Gros       McGill University Montreal, Quebec CANADA
With: Laroque A, Min-Oo G, Tam M, Radovanovic I, Stevenson MM
ContactPhilippe Gros     philippe.gros@mcgill.ca     Lab web site
AcknowledgementsFunding provided by CIHR Team Grant (CTP 79842); McGill University; FRSQ
Project type Phenotype strain survey data set
MPD identifiersGros2     MPD:493
Data changelog No updates/corrections.       Initial release date: 12/2013.
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Summary of procedures that were conducted
• health assessment Survival score and susceptibility, Plasmodium chabaudi.
• microscopy Percent of Plasmodium chabaudi-infected erythrocytes in blood.
Mice: inbred   25 strains   ♀♂   age 8-10wks   1 cohort

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Gros2 49301 microscopy Plasmodium chabaudi percentage of parasite-infected erythrocytes in blood   [%]  parasitemia inbred 22 both 8-10wks N=5
    Gros2 49302 health assessment Plasmodium chabaudi percent survival post-infection (max=21d)   [%]  survival inbred 22 both 8-10wks N=5
    Gros2 49303 health assessment Plasmodium chabaudi response to infection (0=susceptible, 0.5=intermediate, 1=resistant)   [designation]  resistance inbred 22 both 8-10wks N=5
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