Flaherty1: Survey of anxiety-related behaviors in 8 inbred strains of mice using the elevated zero-maze (2001)

Cook MN, Williams RW, Flaherty L. Anxiety-related behaviors in the elevated zero-maze are affected by genetic factors and retinal degeneration. Behav Neurosci. 2001 Apr;115(2):468-76.   PubMed 11345971  


       
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Participants Lorraine Flaherty       Genomics Institute, Wadsworth Center Albany, NY
Melloni N Cook       Genomics Institute, Wadsworth Center Albany, NY
Robert W Williams       University of Tennessee Memphis, TN
ContactLorraine Flaherty     flaherty@wadsworth.org
AcknowledgementsFunding provided by NIH MH58559, EY12991.
Project type Phenotype strain survey data set
MPD identifiersFlaherty1     MPD:118
Data changelog No updates/corrections.       Initial release date: 05/2002.
Formatted citation
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An investigation of anxiety response. In the maze, quadrants 1 and 3 were closed while quadrants 2 and 4 were open. The following were taken as indicators of general anxiety: latency to enter an open quadrant; time in each of the quadrants; total time spent in open and in closed quadrants; activity in the two closed quadrants; and number of fecal boli.

Summary of procedures that were conducted
• elevated zero maze Anxiety-related behaviors.
Mice: inbred   8 strains   ♀♂   age 8-9wks   1 cohort

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Flaherty1 11804 elevated zero maze (none) latency to enter open quadrant   [s]  lat inbred 8 both 8-9wks N=20
    Flaherty1 11805 elevated zero maze (none) duration in open quadrants   [s]     total    q2    q4 inbred 8 both 8-9wks N=20
    Flaherty1 11806 elevated zero maze (none) duration in closed quadrants   [s]     total    q1    q3 inbred 8 both 8-9wks N=20
    Flaherty1 11807 elevated zero maze (none) number beam breaks in closed quadrants   [n/s]  beam_breaks inbred 8 both 8-9wks N=20
    Flaherty1 11813 elevated zero maze (none) percent of time in open quadrants   [%]     both    q2    q4 inbred 8 both 8-9wks N=20
    Flaherty1 11814 elevated zero maze (none) percent of time in closed quadrants   [%]     q1    q3 inbred 8 both 8-9wks N=20
    Flaherty1 11818 elevated zero maze (none) total number fecal boli   [n]  boli inbred 8 both 8-9wks N=20
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