Deschepper1: Systolic blood pressure and multi-organ morphologic characterization in 13 inbred strains of mice (2004)

Deschepper CF, Olson JL, Otis M, Gallo-Payet N. Characterization of blood pressure and morphological traits in cardiovascular-related organs in 13 different inbred mouse strains. J Appl Physiol. 2004 Jul;97(1):369-76. Epub 2004 Mar 26.   PubMed 15047670  


       
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Participants Christian F Deschepper       Institut de Recherches Cliniques de Montreal Montreal, Quebec CANADA
Nicole Gallo-Payet       University of Sherbrooke Sherbrooke, Quebec CANADA
With: Olson JL, Otis M, Picard S
ContactChristian F Deschepper     deschec@ircm.qc.ca
AcknowledgementsFunding provded by NIH HL69122; Group Grant of the Canadian Institutes of Health Research to the IRCM Multidisciplinary Research Group in Hypertension (CIHR MPO-10998)

Generous funds from AstraZeneca were used to defray the cost of mice through the Mouse Phenome Project Collaborations Program.
Project type Phenotype strain survey data set
MPD identifiersDeschepper1     MPD:104
Data changelog 1 update/correction.       Initial release date: 03/2004.
Formatted citation
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Animals were comprehensively assessed for blood pressure, adrenal histology, atrial, ventricular, adrenal, thymus, and kidney weight. This project includes a collection of images.

Summary of procedures that were conducted
• body weight
• organ weights Heart, kidney, thymus, adrena weightsl.
• tail cuff Blood pressure.
Mice: inbred   13 strains   ♀♂   age 10wks   1 cohort

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Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Deschepper1 10401 body weight (none) body weight   [g]  bw inbred 13 both 10wks N=10
    Deschepper1 10402 tail cuff (none) systolic blood pressure   [mmHg]  BP inbred 13 both 10wks N=9
    Deschepper1 10403 organ weights (none) ventricle weight   [mg]     right    left    both inbred 13 both 10wks N=10
    Deschepper1 10404 organ weights (none) ventricle weight, normalized to body weight   [mg]     right    left    both inbred 13 both 10wks N=10
    Deschepper1 10409 organ weights (none) atria weight   [mg]     right    left    both inbred 13 both 10wks N=10
    Deschepper1 10410 organ weights (none) atria weight, normalized to body weight   [mg]     right    left    both inbred 13 both 10wks N=10
    Deschepper1 10415 organ weights (none) thymus weight   [mg]     weight    normalized to bw inbred 13 both 10wks N=10
    Deschepper1 10417 organ weights (none) adrenal weight   [mg]     right    left    both inbred 13 both 10wks N=10
    Deschepper1 10418 organ weights (none) adrenal weight, normalized to body weight   [mg]     right    left    both inbred 13 both 10wks N=10
    Deschepper1 10423 organ weights (none) kidney weight   [mg]     right    left    both inbred 13 both 10wks N=10
    Deschepper1 10424 organ weights (none) kidney weight, normalized to body weight   [mg]     right    left    both inbred 13 both 10wks N=10
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