Chen1: Invariant natural killer T-cells in peripheral blood, spleen, and thymus of 38 inbred strains of mice (2011)

Chen YG, Tsaih SW, Serreze DV. Genetic control of murine invariant natural killer T-cell development dynamically differs dependent on the examined tissue type. Genes Immun. 2012 Feb;13(2):164-74. doi: 10.1038/gene.2011.68. Epub 2011 Sep 22.   PubMed 21938016     FullText


       
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Participants Yi-Guang Chen       Medical College of Wisconsin Milwaukee, WI
David V Serreze       The Jackson Laboratory Bar Harbor, ME
With: Tsaih SW
ContactYi-Guang Chen     yichen@mcw.edu     Lab web site
AcknowledgementsFunding provided by NIH DK46266, DK51090, DK077443
Project type Phenotype strain survey data set
MPD identifiersChen1     MPD:523
Data changelog No updates/corrections.       Initial release date: 10/2014.
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Summary of procedures that were conducted
• immune cell quantification Natural killer T cells in peripheral blood, spleen, thymus.
Mice: inbred   38 strains   ♀♂   age 8-10wks   1 cohort

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Chen1 52301 immune cell quantification (none) percentage of total TCRβ+ cells that are invariant NK T cells, peripheral blood   [%]  pct_iNKT_T_pb inbred 38 m 8-10wks N=4
    Chen1 52302 immune cell quantification (none) percentage of invariant NK T cells that express CD4, peripheral blood   [%]  pct_iNKT_CD4_pb inbred 34 m 8-10wks N=4
    Chen1 52303 immune cell quantification (none) percentage of total TCRβ+ cells that are invariant NK T cells, spleen   [%]  pct_iNKT_T_spleen inbred 38 m 8-10wks N=4
    Chen1 52304 immune cell quantification (none) percentage of invariant NK T cells that express CD4, spleen   [%]  pct_iNKT_CD4_spleen inbred 35 m 8-10wks N=4
    Chen1 52305 immune cell quantification (none) peripheral blood to spleen ratio of invariant NK T cells   [ratio]  iNKT_pb_spl_ratio inbred 38 m 8-10wks N=4
    Chen1 52306 immune cell quantification (none) percentage of total TCRβhi cells that are invariant NK T cells, thymus   [%]  pct_iNKT_T_thymus inbred 38 m 8-10wks N=4
    Chen1 52307 immune cell quantification (none) percentage of invariant NK T cells that express CD4, thymus   [%]  pct_iNKT_CD4_thymus inbred 35 m 8-10wks N=4
    Chen1 52308 immune cell quantification (none) peripheral blood to thymus ratio of invariant NK T cells   [ratio]  iNKT_pb_thy_ratio inbred 38 m 8-10wks N=4
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