Berndt4: Aging study: Pulmonary adenomas in 28 inbred strains of mice, age 20 months (2011)

Berndt A, Cario CL, Silva KA, Kennedy VE, Harrison DE, Paigen B, Sundberg JP. Identification of fat4 and tsc22d1 as novel candidate genes for spontaneous pulmonary adenomas. Cancer Res. 2011 Sep 1;71(17):5779-9doi: 10.1158/0008-5472.CAN-11-1418. Epub 2011 Jul 15.   PubMed 21764761  


       
Berndt4 downloads
• Download Berndt4 strain means, SD, N, etc.     one row per strain/sex/measure
Participants Annerose Berndt       University of Pittsburgh School of Medicine Pittsburgh, PA
David E Harrison       The Jackson Laboratory Bar Harbor, ME
Beverly Paigen       The Jackson Laboratory Bar Harbor, ME
John P Sundberg       The Jackson Laboratory Bar Harbor, ME
With: Cario CL, Silva KA, Kennedy VE
ContactAnnerose Berndt     anb128@pitt.edu     Lab web site
AffiliationJackson Laboratory Nathan Shock Center
AcknowledgementsFunding provided by NIH CA089713, AG025707, AG038070A; the Ellison Medical Foundation; Parker B. Francis Foundation
Project type Phenotype strain survey data set
MPD identifiersBerndt4     MPD:483
Data changelog No updates/corrections.       Initial release date: 08/2013.
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A collection of adenoma images is associated with this project, hosted at MGI's Mouse Tumor Biology Database. An associated gene expression study is available in GEO: GSE30015

Summary of procedures that were conducted
• histopathology Lung adenoma frequency and severity at 20mo. Tumor incidence, cancer, aging.
Mice: inbred   28 strains   ♀♂   age 20mo   1 cohort

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Berndt4 48301 histopathology (none) lung adenoma frequency   [%]  adenoma_freq inbred 28 both 90wks N=10
    Berndt4 48302 histopathology (none) lung adenoma severity score   [score]  adenoma_score inbred 28 both 90wks N=10
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