Procedure:   immune cell quantification          


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Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg) Year
    Benoist1 25801 immune cell quantification (none) percent of thymic CD4 Treg cells that are CD25hi   [%]  Treg_thy_CD25 inbred 33 m 5-6wks N=3 2007
    Benoist1 25802 immune cell quantification (none) percent of thymic CD4 Treg cells that are Foxp3+   [%]  Treg_thy_Foxp3 inbred 10 m 5-6wks N=3 2007
    Benoist1 25803 immune cell quantification (none) percent of splenic CD4 Treg cells that are CD25hi   [%]  Treg_spl_CD25 inbred 31 m 5-6wks N=3 2007
    Benoist1 25804 immune cell quantification (none) percent of splenic CD4 Treg cells that are Foxp3+   [%]  Treg_spl_Foxp3 inbred 10 m 5-6wks N=3 2007
    Chen1 52301 immune cell quantification (none) percentage of total TCRβ+ cells that are invariant NK T cells, peripheral blood   [%]  pct_iNKT_T_pb inbred 38 m 8-10wks N=4 2011
    Chen1 52302 immune cell quantification (none) percentage of invariant NK T cells that express CD4, peripheral blood   [%]  pct_iNKT_CD4_pb inbred 34 m 8-10wks N=4 2011
    Chen1 52303 immune cell quantification (none) percentage of total TCRβ+ cells that are invariant NK T cells, spleen   [%]  pct_iNKT_T_spleen inbred 38 m 8-10wks N=4 2011
    Chen1 52304 immune cell quantification (none) percentage of invariant NK T cells that express CD4, spleen   [%]  pct_iNKT_CD4_spleen inbred 35 m 8-10wks N=4 2011
    Chen1 52305 immune cell quantification (none) peripheral blood to spleen ratio of invariant NK T cells   [ratio]  iNKT_pb_spl_ratio inbred 38 m 8-10wks N=4 2011
    Chen1 52306 immune cell quantification (none) percentage of total TCRβhi cells that are invariant NK T cells, thymus   [%]  pct_iNKT_T_thymus inbred 38 m 8-10wks N=4 2011
    Chen1 52307 immune cell quantification (none) percentage of invariant NK T cells that express CD4, thymus   [%]  pct_iNKT_CD4_thymus inbred 35 m 8-10wks N=4 2011
    Chen1 52308 immune cell quantification (none) peripheral blood to thymus ratio of invariant NK T cells   [ratio]  iNKT_pb_thy_ratio inbred 38 m 8-10wks N=4 2011
    Donahue5 41401 immune cell quantification (none) neutrophil differential (percent of viable WBC)   [%]  pct_NEUT B6.A consomic w/par 22 both 7wks N=8 2011
    Donahue5 41402 immune cell quantification (none) eosinophil differential (percent of viable WBC)   [%]  pct_EOS B6.A consomic w/par 22 both 7wks N=8 2011
    Donahue5 41403 immune cell quantification (none) monocyte differential (percent of viable WBC)   [%]  pct_MONO B6.A consomic w/par 22 both 7wks N=8 2011
    Donahue5 41404 immune cell quantification (none) inflammatory monocytes (percent of viable WBC)   [%]  pct_MONO_inflam B6.A consomic w/par 22 both 7wks N=8 2011
    Donahue5 41405 immune cell quantification (none) resident monocytes (percent of viable WBC)   [%]  pct_MONO_resident B6.A consomic w/par 22 both 7wks N=8 2011
    Donahue5 41406 immune cell quantification (none) B cells (percent of viable WBC)   [%]  pct_B_cells B6.A consomic w/par 22 both 7wks N=8 2011
    Donahue5 41407 immune cell quantification (none) natural killer (NK) cells (percent of viable WBC)   [%]  pct_NK_cells B6.A consomic w/par 22 both 7wks N=8 2011
    Donahue5 41408 immune cell quantification (none) mature natural killer (NK) cells (percent of viable WBC)   [%]  pct_NK_mature B6.A consomic w/par 22 both 7wks N=8 2011
    Donahue5 41409 immune cell quantification (none) T cells (percent of viable WBC)   [%]  pct_T_cells B6.A consomic w/par 22 both 7wks N=8 2011
    Donahue5 41410 immune cell quantification (none) CD4 T cells (percent of viable WBC)   [%]  pct_CD4 B6.A consomic w/par 22 both 7wks N=8 2011
    Donahue5 41412 immune cell quantification (none) CD8 T cells (percent of viable WBC)   [%]  pct_CD8 B6.A consomic w/par 22 both 7wks N=8 2011
    Donahue6 41501 immune cell quantification (none) neutrophil differential (percent of viable WBC)   [%]  pct_NEUT B6.PWD consomic w/par 28 both 7wks N=8 2011
    Donahue6 41502 immune cell quantification (none) eosinophil differential (percent of viable WBC)   [%]  pct_EOS B6.PWD consomic w/par 28 both 7wks N=8 2011
    Donahue6 41503 immune cell quantification (none) monocyte differential (percent of viable WBC)   [%]  pct_MONO B6.PWD consomic w/par 28 both 7wks N=8 2011
    Donahue6 41504 immune cell quantification (none) inflammatory monocytes (percent of viable WBC)   [%]  pct_MONO_inflam B6.PWD consomic w/par 28 both 7wks N=8 2011
    Donahue6 41505 immune cell quantification (none) resident monocytes (percent of viable WBC)   [%]  pct_MONO_resident B6.PWD consomic w/par 28 both 7wks N=8 2011
    Donahue6 41506 immune cell quantification (none) B cells (percent of viable WBC)   [%]  pct_B_cells B6.PWD consomic w/par 28 both 7wks N=8 2011
    Donahue6 41507 immune cell quantification (none) natural killer (NK) cells (percent of viable WBC)   [%]  pct_NK_cells B6.PWD consomic w/par 28 both 7wks N=8 2011
    Donahue6 41508 immune cell quantification (none) mature natural killer (NK) cells (percent of viable WBC)   [%]  pct_NK_mature B6.PWD consomic w/par 28 both 7wks N=8 2011
    Donahue6 41509 immune cell quantification (none) T cells (percent of viable WBC)   [%]  pct_T_cells B6.PWD consomic w/par 28 both 7wks N=8 2011
    Donahue6 41510 immune cell quantification (none) CD4 T cells (percent of viable WBC)   [%]  pct_CD4 B6.PWD consomic w/par 28 both 7wks N=8 2011
    Donahue6 41511 immune cell quantification (none) CD8 T cells (percent of viable WBC)   [%]  pct_CD8 B6.PWD consomic w/par 28 both 7wks N=8 2011
Farmer1 11333 immune cell quantification (none) percentage of Interleukin 12 in collected blood   [%]  IL12 QTL population both 6wks N=206 2001
Farmer1 11334 immune cell quantification (none) percentagse of viable CD4+ T cells in 150 µl collected blood   [%]  CD4 QTL population both 6wks N=206 2001
Farmer1 11335 immune cell quantification (none) percentagse of viable CD8+ T cells in 150 µl collected blood   [%]  CD8 QTL population both 6wks N=206 2001
Farmer1 11336 immune cell quantification (none) percentagse of viable B220+ B cells in 150 µl collected blood   [%]  B220 QTL population both 6wks N=206 2001
Farmer1 11337 immune cell quantification (none) percentagse of viable IgM+ B cells in 150 µl collected blood   [%]  lgM QTL population both 6wks N=206 2001
Farmer1 11338 immune cell quantification (none) percentagse of macrophages in 150 µl collected blood   [%]  Macrophages QTL population both 6wks N=206 2001
Farmer1 11339 immune cell quantification (none) percentagse of viable granulocytes in 150 µl collected blood   [%]  Granulocytes QTL population both 6wks N=206 2001
    Hackstein1 49101 immune cell quantification (none) total leukocyte count (x 103)   [n]  BAL inbred 5 m 7-11wks N=5 2012
    Hackstein1 49102 immune cell quantification (none) macrophages (percentage of BAL leukocytes)   [%]  BAL_MAC inbred 5 m 7-11wks N=5 2012
    Hackstein1 49103 immune cell quantification (none) dendritic cells (percentage of CD45+ cells)   [%]  DC inbred 5 m 7-11wks N=9 2012
    Hackstein1 49104 immune cell quantification (none) plasmacytoid dendritic cells (percentage of CD45+ cells)   [%]  DC_plasmacytoid inbred 5 m 7-11wks N=9 2012
    Hackstein1 49105 immune cell quantification (none) monocytic dendritic cells (percentage of CD45+ cells)   [%]  DC_monocytic inbred 5 m 7-11wks N=9 2012
    Hackstein1 49106 immune cell quantification (none) CD103+ dendritic cells (percentage of CD45+ cells)   [%]  DC_103 inbred 5 m 7-11wks N=9 2012
    Hackstein1 49107 immune cell quantification (none) CD11bhi MHChi dendritic cells (percentage of CD45+ cells)   [%]  DC_11b inbred 5 m 7-11wks N=9 2012
    Hackstein1 49108 immune cell quantification (none) Siglec F+ F4/80+ macrophages (percentage of CD45+ cells)   [%]  MAC inbred 5 m 7-11wks N=9 2012
    Hackstein1 49109 immune cell quantification (none) neutrophils (percentage of CD45+ cells)   [%]  NEUT inbred 5 m 7-11wks N=9 2012
    Hackstein1 49110 immune cell quantification (none) eosinophils (percentage of CD45+ cells)   [%]  EOS inbred 5 m 7-11wks N=9 2012
    Hackstein1 49111 immune cell quantification (none) Linneg CD90+ innate cells (percentage of CD45+ cells)   [%]  Lin_neg_90_plus inbred 5 m 7-11wks N=6 2012
    Hackstein1 49112 immune cell quantification (none) Linneg CD90- innate cells (percentage of CD45+ cells)   [%]  Lin_neg_90_neg inbred 5 m 7-11wks N=6 2012
    Hackstein1 49113 immune cell quantification (none) CD19+ B cells (percentage of CD45+ cells)   [%]  B_cells inbred 5 m 7-11wks N=8 2012
    Hackstein1 49114 immune cell quantification (none) CD3+ T cells (percentage of CD45+ cells)   [%]  T_CD3 inbred 5 m 7-11wks N=9 2012
    Hackstein1 49115 immune cell quantification (none) CD3+ CD8+ T cells (percentage of CD45+ cells)   [%]  T_CD8 inbred 5 m 7-11wks N=9 2012
    Hackstein1 49116 immune cell quantification (none) CD3+ CD4+ T cells (percentage of CD45+ cells)   [%]  T_CD4 inbred 5 m 7-11wks N=9 2012
    Hackstein1 49117 immune cell quantification (none) CD3+ CD4+ CD25+ T cells (percentage of CD45+ cells)   [%]  T_CD4_25 inbred 5 m 7-11wks N=8 2012
    Hackstein1 49118 immune cell quantification (none) CD3+ CD4+ CD25hi Treg cells (percentage of CD45+ cells)   [%]  T_CD4_25hi inbred 5 m 7-11wks N=5 2012
    Hackstein1 49119 immune cell quantification (none) CD3+ CD4+ CD25hi Foxp3+ Treg cells (percentage of CD45+ cells)   [%]  T_CD4_foxp3 inbred 5 m 7-11wks N=5 2012
    Hackstein1 49120 immune cell quantification (none) CD3+ CD4+ CD25hi Foxp3+ CD39+ Treg cells (percentage of CD45+ cells)   [%]  T_CD4_39 inbred 5 m 7-11wks N=5 2012
    Hackstein1 49121 immune cell quantification (none) CD3+ gamma-delta T cells (percentage of CD45+ cells)   [%]  T_gd inbred 5 m 7-11wks N=9 2012
    Hackstein1 49122 immune cell quantification (none) CD49+ natural killer (NK) cells (percentage of CD45+ cells)   [%]  NK inbred 5 m 7-11wks N=9 2012
    Jaxpheno6 23101 immune cell quantification (none) CD4 T cells   [%]     8wks    16wks inbred 11 both 8wks, 16wks N=9 2006
    Jaxpheno6 23103 immune cell quantification (none) CD8 T cells   [%]     8wks    16wks inbred 11 both 8wks, 16wks N=9 2006
    Jaxpheno6 23105 immune cell quantification (none) NK T cells   [%]     8wks    16wks inbred 11 both 8wks, 16wks N=9 2006
    Jaxpheno6 23107 immune cell quantification (none) NK cells   [%]     8wks    16wks inbred 11 both 8wks, 16wks N=9 2006
    Jaxpheno6 23109 immune cell quantification (none) B cells   [%]     8wks    16wks inbred 11 both 8wks, 16wks N=9 2006
    Jaxpheno6 23120 immune cell quantification (none) granulocytes   [%]     8wks    16wks inbred 11 both 8wks, 16wks N=9 2006
    Jaxpheno6 23122 immune cell quantification (none) monocytes   [%]     8wks    16wks inbred 11 both 8wks, 16wks N=9 2006
    Petkova1 24225 immune cell quantification (none) B cells   [%]     6mo    12mo    18mo    24mo inbred 32 both None N=7 2007
    Petkova1 24229 immune cell quantification (none) CD4 T cells   [%]     6mo    12mo    18mo    24mo inbred 32 both None N=8 2007
    Petkova1 24233 immune cell quantification (none) CD4 T cells - naive cells   [%]     6mo    12mo    18mo    24mo inbred 32 both None N=8 2007
    Petkova1 24237 immune cell quantification (none) CD4 T cells - central memory cells   [%]     6mo    12mo    18mo    24mo inbred 32 both None N=8 2007
    Petkova1 24241 immune cell quantification (none) CD4 T cells - effector memory cells   [%]     6mo    12mo    18mo    24mo inbred 32 both None N=8 2007
    Petkova1 24246 immune cell quantification (none) CD4 T cells - effector cells   [%]     6mo    12mo    18mo    24mo inbred 32 both None N=8 2007
    Petkova1 24251 immune cell quantification (none) CD8 T cells   [%]     6mo    12mo    18mo    24mo inbred 32 both None N=8 2007
    Petkova1 24256 immune cell quantification (none) CD8 T cells - naive cells   [%]     6mo    12mo    18mo    24mo inbred 32 both None N=8 2007
    Petkova1 24261 immune cell quantification (none) CD8 T cells - central memory cells   [%]     6mo    12mo    18mo    24mo inbred 32 both None N=8 2007
    Petkova1 24266 immune cell quantification (none) CD8 T cells - effector memory cells   [%]     6mo    12mo    18mo    24mo inbred 32 both None N=8 2007
    Petkova1 24271 immune cell quantification (none) CD8 T cells - effector cells   [%]     6mo    12mo    18mo    24mo inbred 32 both None N=8 2007
    Petkova1 24276 immune cell quantification (none) NK cells   [%]     6mo    12mo    18mo    24mo inbred 32 both None N=8 2007
    Williams1 42901 immune cell quantification (none) CD4 Treg cells (CD25+ CD44int; as percent of lymphocytes)   [%]  Treg inbred 5 f 8wks N=3 2012
    Williams1 42902 immune cell quantification (none) CD4 Treg cells (CD25+ CD44int; as percent of CD4 T cells)   [%]  Treg_adj inbred 5 f 8wks N=3 2012
    Williams1 42903 immune cell quantification (none) memory-effector CD4 T cells (CD25- CD44hi; as percent of lymphocytes)   [%]  memoryT inbred 5 f 8wks N=3 2012
    Williams1 42904 immune cell quantification (none) memory-effector CD4 T cells (CD25- CD44hi; as percent of CD4 T cells)   [%]  memoryT_adj inbred 5 f 8wks N=3 2012
    Williams1 42905 immune cell quantification (none) naive CD4 T cells (CD25- CD44lo; as percent of lymphocytes)   [%]  naiveT inbred 5 f 8wks N=3 2012
    Williams1 42906 immune cell quantification (none) naive CD4 T cells (CD25- CD44lo; as percent of CD4 T cells)   [%]  naiveT_adj inbred 5 f 8wks N=3 2012
    Wiltshire4 52401 immune cell quantification BEZ235 B cells % viability   [%]     dose [µM]:    control    0.046    0.137    1.235    11.1    100 inbred w/CC7 34 m 10wks N=4 2015
    Wiltshire4 52407 immune cell quantification BEZ235 T cells % viability   [%]     dose [µM]:    control    0.046    0.137    1.235    11.1    100 inbred w/CC7 34 m 10wks N=4 2015
    Wiltshire4 52413 immune cell quantification BEZ235 monocytes % viability   [%]     dose [µM]:    control    0.046    0.137    1.235    11.1    100 inbred w/CC7 34 m 10wks N=4 2015
    Wiltshire4 52421 immune cell quantification doxorubicin B cells % viability   [%]     dose [µM]:    control    0.046    0.137    1.235    11.1    100 inbred w/CC7 35 m 10wks N=4 2015
    Wiltshire4 52427 immune cell quantification doxorubicin T cells % viability   [%]     dose [µM]:    control    0.046    0.137    1.235    11.1    100 inbred w/CC7 35 m 10wks N=4 2015
    Wiltshire4 52433 immune cell quantification doxorubicin monocytes % viability   [%]     dose [µM]:    control    0.046    0.137    1.235    11.1    100 inbred w/CC7 35 m 10wks N=4 2015
    Wiltshire4 52441 immune cell quantification idarubicin B cells % viability   [%]     dose [µM]:    control    0.046    0.137    1.235    11.1    100 inbred w/CC7 35 m 10wks N=4 2015
    Wiltshire4 52447 immune cell quantification idarubicin T cells % viability   [%]     dose [µM]:    control    0.046    0.137    1.235    11.1    100 inbred w/CC7 35 m 10wks N=4 2015
    Wiltshire4 52453 immune cell quantification idarubicin monocytes % viability   [%]     dose [µM]:    control    0.046    0.137    1.235    11.1    100 inbred w/CC7 35 m 10wks N=4 2015
    Wiltshire4 52461 immune cell quantification selumetinib B cells % viability   [%]     dose [µM]:    control    0.046    0.137    1.235    11.1    100 inbred w/CC7 34 m 10wks N=4 2015
    Wiltshire4 52467 immune cell quantification selumetinib T cells % viability   [%]     dose [µM]:    control    0.046    0.137    1.235    11.1    100 inbred w/CC7 34 m 10wks N=4 2015
    Wiltshire4 52473 immune cell quantification selumetinib monocytes % viability   [%]     dose [µM]:    control    0.046    0.137    1.235    11.1    100 inbred w/CC7 34 m 10wks N=4 2015
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