MPD: Project measures / variables set: Korstanje2 pct

Project measures / variables set: Korstanje2 pct_MME

ID, description, units	MPD:51001 pct_MME percentage of glomeruli exhibiting mesangial matrix expansion [%]
Measures	• 6mo • 12mo • 20mo
Data set, strains	Korstanje2 inbred 29 strains sex: m
Procedure	histopathology
Comparison	aging-study, multiple cohorts
Ontology mappings	VT:0005327 mesangial cell morphology trait MA:0000368 kidney MP:0011339 abnormal glomerular mesangium morphology

Values Means Δ Means Z-scores

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Korstanje2 - percentage of glomeruli exhibiting mesangial matrix expansion

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
age	2	6739.7126	3369.8563	30.0756	< 0.0001
age:strain	10	2214.2715	221.4272	1.9762	0.0466
Residuals	81	9075.7417	112.0462
strain	5	722.0684	144.4137	1.2889	0.2768

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Korstanje2	51001	histopathology	(none)	percentage of glomeruli exhibiting mesangial matrix expansion [%] at age 6mo pct_MME_M06	inbred	7	m	26wks
Korstanje2	51002	histopathology	(none)	percentage of glomeruli exhibiting mesangial matrix expansion [%] at age 12mo pct_MME_M12	inbred	20	m	52wks
Korstanje2	51003	histopathology	(none)	percentage of glomeruli exhibiting mesangial matrix expansion [%] at age 20mo pct_MME_M20	inbred	27	m	87wks