MPD: Project measures / variables set: Rusyn5 total

Project measures / variables set: Rusyn5 total_pathology

ID, description, units	MPD:43019 total_pathology total liver histopathology (0-8) [score] high-fat diet and ethanol study
Measures	• high-fat only • high-fat and ethanol
Data set, strains	Rusyn5 inbred 14 strains sex: m age: 8-14wks
Procedure	histopathology
Comparison	control group vs. treated group
Ontology mappings	VT:0000598 liver morphology trait VT:0010489 response to alcohol trait MA:0000358 liver MP:0000598 abnormal liver morphology

Values Means Δ Means Z-scores

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Rusyn5 - total liver histopathology (0-8)

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	102.9643	102.9643	161.6636	< 0.0001
group:strain	13	36.9524	2.8425	4.463	< 0.0001
Residuals	56	35.6667	0.6369
strain	13	52.9762	4.0751	6.3983	< 0.0001

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Rusyn5	43019	histopathology	high-fat diet and ethanol	total liver histopathology (0-8) [score] high-fat only total_pathology_hf	inbred	14	m	8-14wks
Rusyn5	43020	histopathology	high-fat diet and ethanol	total liver histopathology (0-8) [score] high-fat and ethanol total_pathology_hfe	inbred	14	m	8-14wks