MPD: Project measures / variables set: Rusyn5 inflammation

Project measures / variables set: Rusyn5 inflammation

ID, description, units	MPD:43015 inflammation liver inflammation (0-2) [score] high-fat diet and ethanol study
Measures	• high-fat only • high-fat and ethanol
Data set, strains	Rusyn5 inbred 14 strains sex: m age: 8-14wks
Procedure	histopathology
Comparison	control group vs. treated group
Ontology mappings	VT:0000598 liver morphology trait VT:0010489 response to alcohol trait MA:0000358 liver MP:0000598 abnormal liver morphology

Values Means Δ Means Z-scores

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Rusyn5 - liver inflammation (0-2)

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	0.0268	0.0268	0.1552	0.6951
group:strain	13	4.3482	0.3345	1.9377	0.0449
Residuals	56	9.6667	0.1726
strain	13	14.4673	1.1129	6.4469	< 0.0001

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Rusyn5	43015	histopathology	high-fat diet and ethanol	liver inflammation (0-2) [score] high-fat only inflammation_hf	inbred	14	m	8-14wks
Rusyn5	43016	histopathology	high-fat diet and ethanol	liver inflammation (0-2) [score] high-fat and ethanol inflammation_hfe	inbred	14	m	8-14wks