MPD: Project measures / variables set: Harrill1 hypertro

Project measures / variables set: Harrill1 hypertro_pan

ID, description, units	MPD:39556 hypertro_pan hepatocytic hypertrophy, panlobular, diffuse [score] isoniazid study
Measures	• control • isoniazid
Data set, strains	Harrill1 inbred 34 strains sex: f age: 8-10wks
Procedure	histopathology
Comparison	control group vs. treated group
Ontology mappings	VT:0000607 hepatocyte morphology trait VT:0010487 response to xenobiotic stimulus trait MA:0000358 liver MP:0000598 abnormal liver morphology MP:0000607 abnormal hepatocyte morphology

Values Means Δ Means Z-scores

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Harrill1 - hepatocytic hypertrophy, panlobular, diffuse

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	1.9229	1.9229	7.5546	0.0065
group:strain	33	40.1324	1.2161	4.7778	< 0.0001
Residuals	202	51.4167	0.2545
strain	33	180.9132	5.4822	21.5379	< 0.0001

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Harrill1	39556	histopathology	isoniazid	hepatocytic hypertrophy, panlobular, diffuse [score] control hypertro_pan_ctrl	inbred	34	f	8-10wks
Harrill1	39557	histopathology	isoniazid	hepatocytic hypertrophy, panlobular, diffuse [score] isoniazid hypertro_pan_trt	inbred	34	f	8-10wks